Scott Boyken
Scott Boyken
University of Washington
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Cited by
Cited by
The coming of age of de novo protein design
PS Huang, SE Boyken, D Baker
Nature 537 (7620), 320-327, 2016
De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity
SE Boyken, Z Chen, B Groves, RA Langan, G Oberdorfer, A Ford, ...
Science 352 (6286), 680-687, 2016
Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport
F Long, CC Su, MT Zimmermann, SE Boyken, KR Rajashankar, ...
Nature 467 (7314), 484-488, 2010
De novo design of bioactive protein switches
RA Langan, SE Boyken, AH Ng, JA Samson, G Dods, AM Westbrook, ...
Nature 572 (7768), 205-210, 2019
Programmable design of orthogonal protein heterodimers
Z Chen, SE Boyken, M Jia, F Busch, D Flores-Solis, MJ Bick, P Lu, ...
Nature 565 (7737), 106-111, 2019
Accurate computational design of multipass transmembrane proteins
P Lu, D Min, F DiMaio, KY Wei, MD Vahey, SE Boyken, Z Chen, JA Fallas, ...
Science 359 (6379), 1042-1046, 2018
Macromolecular modeling and design in Rosetta: recent methods and frameworks
JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ...
Nature methods 17 (7), 665-680, 2020
De novo design of tunable, pH-driven conformational changes
SE Boyken, MA Benhaim, F Busch, M Jia, MJ Bick, H Choi, JC Klima, ...
Science 364 (6441), 658-664, 2019
De novo design of protein logic gates
Z Chen, RD Kibler, A Hunt, F Busch, J Pearl, M Jia, ZL VanAernum, ...
Science 368 (6486), 78-84, 2020
Modular and tunable biological feedback control using a de novo protein switch
AH Ng, TH Nguyen, M Gomez-Schiavon, G Dods, RA Langan, SE Boyken, ...
Nature 572 (7768), 265-269, 2019
Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain
A Severin, RE Joseph, S Boyken, DB Fulton, AH Andreotti
Journal of molecular biology 387 (3), 726-743, 2009
Dynamic allostery mediated by a conserved tryptophan in the Tec family kinases
N Chopra, TE Wales, RE Joseph, SE Boyken, JR Engen, RL Jernigan, ...
PLoS computational biology 12 (3), e1004826, 2016
Rapid sampling of hydrogen bond networks for computational protein design
JB Maguire, SE Boyken, D Baker, B Kuhlman
Journal of chemical theory and computation 14 (5), 2751-2760, 2018
Rapid online buffer exchange for screening of proteins, protein complexes and cell lysates by native mass spectrometry
ZL VanAernum, F Busch, BJ Jones, M Jia, Z Chen, SE Boyken, ...
Nature protocols 15 (3), 1132-1157, 2020
Rates of molecular evolution vary in vertebrates for insulin-like growth factor-1 (IGF-1), a pleiotropic locus that regulates life history traits
AM Sparkman, TS Schwartz, JA Madden, SE Boyken, NB Ford, JM Serb, ...
General and comparative endocrinology 178 (1), 164-173, 2012
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
KY Wei, D Moschidi, MJ Bick, S Nerli, AC McShan, LP Carter, PS Huang, ...
Proceedings of the National Academy of Sciences 117 (13), 7208-7215, 2020
Calmodulin and PI (3, 4, 5) P3 cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production
X Wang, SE Boyken, J Hu, X Xu, RP Rimer, MA Shea, AS Shaw, ...
Science signaling 7 (337), ra74-ra74, 2014
Designed protein logic to target cells with precise combinations of surface antigens
MJ Lajoie, SE Boyken, AI Salter, J Bruffey, A Rajan, RA Langan, ...
Science 369 (6511), 1637-1643, 2020
Computational design of transmembrane pores
C Xu, P Lu, TMG El-Din, XY Pei, MC Johnson, A Uyeda, MJ Bick, Q Xu, ...
Nature 585 (7823), 129-134, 2020
Self-Assembling 2D Arrays with de Novo Protein Building Blocks
Z Chen, MC Johnson, J Chen, MJ Bick, SE Boyken, B Lin, JJ De Yoreo, ...
Journal of the American Chemical Society 141 (22), 8891-8895, 2019
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