| Advanced Real‐Time Process Analytics for Multistep Synthesis in Continuous Flow P Sagmeister, R Lebl, I Castillo, J Rehrl, J Kruisz, M Sipek, M Horn, ... Angewandte Chemie International Edition 60 (15), 8139-8148, 2021 | 121 | 2021 |
| Laboratory of the future: a modular flow platform with multiple integrated PAT tools for multistep reactions P Sagmeister, JD Williams, C Hone, CO Kappe Reaction Chemistry & Engineering 4 (9), 1571-1578, 2019 | 98 | 2019 |
| Visible-Light-Mediated Iodoperfluoroalkylation of Alkenes in Flow and Its Application to the Synthesis of a Key Fulvestrant Intermediate C Rosso, JD Williams, G Filippini, M Prato, CO Kappe Organic Letters 21 (13), 5341-5345, 2019 | 84 | 2019 |
| Oscillatory flow reactors for synthetic chemistry applications P Bianchi, JD Williams, CO Kappe Journal of Flow Chemistry 10 (3), 475-490, 2020 | 81 | 2020 |
| Recent advances toward sustainable flow photochemistry JD Williams, CO Kappe Current Opinion in Green and Sustainable Chemistry 25, 100351, 2020 | 78 | 2020 |
| An oscillatory plug flow photoreactor facilitates semi-heterogeneous dual nickel/carbon nitride photocatalytic C–N couplings C Rosso, S Gisbertz, JD Williams, HPL Gemoets, W Debrouwer, B Pieber, ... Reaction Chemistry & Engineering 5 (3), 597-604, 2020 | 75 | 2020 |
| Continuous Flow Synthesis of ZIF‐8 Biocomposites with Tuneable Particle Size F Carraro, J Williams, M Linares-Moreau, C Parise, W Liang, H Amenitsch, ... Angewandte Chemie International Edition 59 (21), 8200-8204, 2020 | 70 | 2020 |
| Finding the Perfect Match: A Combined Computational and Experimental Study toward Efficient and Scalable Photosensitized [2+ 2] Cycloadditions in Flow JD Williams, M Nakano, R Gérardy, JA Rincón, Ó de Frutos, C Mateos, ... Organic Process Research & Development 23 (1), 78-87, 2019 | 67 | 2019 |
| Multikilogram per Hour Continuous Photochemical Benzylic Brominations Applying a Smart Dimensioning Scale-up Strategy A Steiner, PMC Roth, F Strauß, G Gauron, G Tekautz, M Winter, ... Organic Process Research & Development 24 (10), 2208-2216, 2020 | 61 | 2020 |
| The Right Light: De Novo Design of a Robust Modular Photochemical Reactor for Optimum Batch and Flow Chemistry HE Bonfield, K Mercer, A Diaz‐Rodriguez, GC Cook, BSJ McKay, P Slade, ... ChemPhotoChem 4 (1), 45-51, 2020 | 58 | 2020 |
| Continuous photochemical benzylic bromination using in situ generated Br 2: process intensification towards optimal PMI and throughput A Steiner, JD Williams, O de Frutos, JA Rincón, C Mateos, CO Kappe Green Chemistry 22 (1), 448-454, 2020 | 53 | 2020 |
| Autonomous Multi‐Step and Multi‐Objective Optimization Facilitated by Real‐Time Process Analytics P Sagmeister, FF Ort, CE Jusner, D Hebrault, T Tampone, FG Buono, ... Advanced Science 9 (10), 2105547, 2022 | 41 | 2022 |
| Multivariate analysis of inline benchtop NMR data enables rapid optimization of a complex nitration in flow P Sagmeister, J Poms, JD Williams, CO Kappe Reaction Chemistry & Engineering 5 (4), 677-684, 2020 | 41 | 2020 |
| Continuous Flow C-Glycosylation via Metal–Halogen Exchange: Process Understanding and Improvements toward Efficient Manufacturing of Remdesivir T von Keutz, JD Williams, CO Kappe Organic Process Research & Development 24 (10), 2362−2368, 2020 | 35 | 2020 |
| Continuous flow processing of bismuth-photocatalyzed atom transfer radical addition reactions using an oscillatory flow reactor P Bianchi, JD Williams, CO Kappe Green Chemistry 23 (7), 2685-2693, 2021 | 32 | 2021 |
| Flash Chemistry Approach to Organometallic C-Glycosylation for the Synthesis of Remdesivir T von Keutz, JD Williams, CO Kappe Organic Process Research & Development 25 (4), 1015-1021, 2021 | 28 | 2021 |
| A Detailed Study of Irradiation Requirements Towards an Efficient Photochemical Wohl‐Ziegler Procedure in Flow HE Bonfield, JD Williams, WX Ooi, SG Leach, WJ Kerr, LJ Edwards ChemPhotoChem 2 (10), 938-944, 2018 | 28 | 2018 |
| A practical and general amidation method from isocyanates enabled by flow technology JD Williams, WJ Kerr, SG Leach, DM Lindsay Angewandte Chemie International Edition 57 (37), 12126-12130, 2018 | 25 | 2018 |
| Identification and optimisation of 7-azaindole PAK1 inhibitors with improved potency and kinase selectivity W McCoull, EJ Hennessy, K Blades, MR Box, C Chuaqui, JE Dowling, ... MedChemComm 5 (10), 1533-1539, 2014 | 24 | 2014 |
| Implementing Hydrogen Atom Transfer (HAT) Catalysis for Rapid and Selective Reductive Photoredox Transformations in Continuous Flow A Steiner, JD Williams, JA Rincón, O de Frutos, C Mateos, CO Kappe European Journal of Organic Chemistry, 5807-5811, 2019 | 21 | 2019 |
