From Krebs to clinic: glutamine metabolism to cancer therapy BJ Altman, ZE Stine, CV Dang Nature Reviews Cancer 16 (10), 619-634, 2016 | 1911 | 2016 |
MYC, metabolism, and cancer ZE Stine, ZE Walton, BJ Altman, AL Hsieh, CV Dang Cancer discovery 5 (10), 1024-1039, 2015 | 1114* | 2015 |
Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis Y Xiang, ZE Stine, J Xia, Y Lu, RS O’Connor, BJ Altman, AL Hsieh, ... The Journal of clinical investigation 125 (6), 2293-2306, 2015 | 444 | 2015 |
MYC and metabolism on the path to cancer AL Hsieh, ZE Walton, BJ Altman, ZE Stine, CV Dang Seminars in cell & developmental biology 43, 11-21, 2015 | 303 | 2015 |
MYC disrupts the circadian clock and metabolism in cancer cells BJ Altman, AL Hsieh, A Sengupta, SY Krishnanaiah, ZE Stine, ZE Walton, ... Cell metabolism 22 (6), 1009-1019, 2015 | 265 | 2015 |
Glycogen Synthase Kinase 3α and 3β Mediate a Glucose-Sensitive Antiapoptotic Signaling Pathway To Stabilize Mcl-1 Y Zhao, BJ Altman, JL Coloff, CE Herman, SR Jacobs, HL Wieman, ... Molecular and cellular biology 27 (12), 4328-4339, 2007 | 221 | 2007 |
Metabolic stress in autophagy and cell death pathways BJ Altman, JC Rathmell Cold Spring Harbor perspectives in biology 4 (9), a008763, 2012 | 219 | 2012 |
Clock regulation of metabolites reveals coupling between transcription and metabolism SY Krishnaiah, G Wu, BJ Altman, J Growe, SD Rhoades, F Coldren, ... Cell metabolism 25 (4), 961-974. e4, 2017 | 192 | 2017 |
Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis BJ Altman, SR Jacobs, EF Mason, RD Michalek, AN MacIntyre, JL Coloff, ... Oncogene 30 (16), 1855-1867, 2011 | 151 | 2011 |
The MYC oncogene cooperates with sterol-regulated element-binding protein to regulate lipogenesis essential for neoplastic growth AM Gouw, K Margulis, NS Liu, SJ Raman, A Mancuso, GG Toal, L Tong, ... Cell metabolism 30 (3), 556-572. e5, 2019 | 145 | 2019 |
ER stress modulates cellular metabolism X Wang, CO Eno, BJ Altman, Y Zhu, G Zhao, KE Olberding, JC Rathmell, ... Biochemical Journal 435 (1), 285-296, 2011 | 137 | 2011 |
Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells JL Coloff, EF Mason, BJ Altman, VA Gerriets, T Liu, AN Nichols, Y Zhao, ... Journal of Biological Chemistry 286 (7), 5921-5933, 2011 | 118 | 2011 |
A PERK–miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival Y Bu, A Yoshida, N Chitnis, BJ Altman, F Tameire, A Oran, V Gennaro, ... Nature cell biology 20 (1), 104-115, 2018 | 99 | 2018 |
Human THAP7 is a chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressor T Macfarlan, S Kutney, B Altman, R Montross, J Yu, D Chakravarti Journal of Biological Chemistry 280 (8), 7346-7358, 2005 | 88 | 2005 |
Normal and cancer cell metabolism: lymphocytes and lymphoma BJ Altman, CV Dang The FEBS journal 279 (15), 2598-2609, 2012 | 80 | 2012 |
An essential role for the Glut1 PDZ-binding motif in growth factor regulation of Glut1 degradation and trafficking HL Wieman, SR Horn, SR Jacobs, BJ Altman, S Kornbluth, JC Rathmell Biochemical Journal 418 (2), 345-367, 2009 | 74 | 2009 |
Autophagy Provides Nutrients but Can Lead to Chop-dependent Induction of Bim to Sensitize Growth Factor–deprived Cells to Apoptosis BJ Altman, JA Wofford, Y Zhao, JL Coloff, EC Ferguson, HL Wieman, ... Molecular biology of the cell 20 (4), 1180-1191, 2009 | 61 | 2009 |
Cancer clocks out for lunch: Disruption of circadian rhythm and metabolic oscillation in cancer BJ Altman Frontiers in cell and developmental biology 4, 62, 2016 | 57 | 2016 |
Autophagy: not good OR bad, but good AND bad BJ Altman, JC Rathmell Autophagy 5 (4), 569-570, 2009 | 29 | 2009 |
Myc-mediated transcriptional regulation of the mitochondrial chaperone TRAP1 controls primary and metastatic tumor growth E Agarwal, BJ Altman, JH Seo, JC Ghosh, AV Kossenkov, HY Tang, ... Journal of Biological Chemistry 294 (27), 10407-10414, 2019 | 28 | 2019 |