| NARC-1/PCSK9 and its natural mutants zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol S Benjannet, D Rhainds, R Essalmani, J Mayne, L Wickham, W Jin, ... Journal of Biological Chemistry 279 (47), 48865-48875, 2004 | 789 | 2004 |
| Plasma PCSK9 levels are significantly modified by statins and fibrates in humans J Mayne, T Dewpura, A Raymond, M Cousins, A Chaplin, KA Lahey, ... Lipids in health and disease 7 (1), 22, 2008 | 268 | 2008 |
| PCSK9‐deficient mice exhibit impaired glucose tolerance and pancreatic islet abnormalities M Mbikay, F Sirois, J Mayne, GS Wang, A Chen, T Dewpura, A Prat, ... FEBS letters 584 (4), 701-706, 2010 | 241 | 2010 |
| Metaproteomics reveals associations between microbiome and intestinal extracellular vesicle proteins in pediatric inflammatory bowel disease X Zhang, SA Deeke, Z Ning, AE Starr, J Butcher, J Li, J Mayne, K Cheng, ... Nature communications 9 (1), 2873, 2018 | 225 | 2018 |
| MetaPro-IQ: a universal metaproteomic approach to studying human and mouse gut microbiota X Zhang, Z Ning, J Mayne, JI Moore, J Li, J Butcher, SA Deeke, R Chen, ... Microbiome 4 (1), 31, 2016 | 165 | 2016 |
| Novel loss-of-function PCSK9 variant is associated with low plasma LDL cholesterol in a French-Canadian family and with impaired processing and secretion in cell culture J Mayne, T Dewpura, A Raymond, L Bernier, M Cousins, TC Ooi, ... Clinical chemistry 57 (10), 1415-1423, 2011 | 131 | 2011 |
| Plasma PCSK9 levels correlate with cholesterol in men but not in women J Mayne, A Raymond, A Chaplin, M Cousins, N Kaefer, ... Biochemical and biophysical research communications 361 (2), 451-456, 2007 | 114 | 2007 |
| MetaLab: an automated pipeline for metaproteomic data analysis K Cheng, Z Ning, X Zhang, L Li, B Liao, J Mayne, A Stintzi, D Figeys Microbiome 5 (1), 157, 2017 | 110 | 2017 |
| Assessing the impact of protein extraction methods for human gut metaproteomics X Zhang, L Li, J Mayne, Z Ning, A Stintzi, D Figeys Journal of proteomics 180, 120-127, 2018 | 100 | 2018 |
| PCSK9 is phosphorylated by a Golgi casein kinase‐like kinase ex vivo and circulates as a phosphoprotein in humans T Dewpura, A Raymond, J Hamelin, NG Seidah, M Mbikay, M Chrétien, ... The FEBS journal 275 (13), 3480-3493, 2008 | 97 | 2008 |
| An in vitro model maintaining taxon-specific functional activities of the gut microbiome L Li, E Abou-Samra, Z Ning, X Zhang, J Mayne, J Wang, K Cheng, ... bioRxiv, 616656, 2019 | 93 | 2019 |
| Quercetin-3-glucoside increases low-density lipoprotein receptor (LDLR) expression, attenuates proprotein convertase subtilisin/kexin 9 (PCSK9) secretion, and stimulates LDL … M Mbikay, F Sirois, S Simoes, J Mayne, M Chrétien FEBS open bio 4, 755-762, 2014 | 88 | 2014 |
| Bottom-up proteomics (2013–2015): Keeping up in the era of systems biology J Mayne, Z Ning, X Zhang, AE Starr, R Chen, S Deeke, CK Chiang, B Xu, ... Analytical chemistry 88 (1), 95-121, 2015 | 78 | 2015 |
| Deep metaproteomics approach for the study of human microbiomes X Zhang, W Chen, Z Ning, J Mayne, D Mack, A Stintzi, R Tian, D Figeys Analytical chemistry 89 (17), 9407-9415, 2017 | 76 | 2017 |
| Differential effects of PCSK9 loss of function variants on serum lipid and PCSK9 levels in Caucasian and African Canadian populations J Mayne, TC Ooi, A Raymond, M Cousins, L Bernier, T Dewpura, F Sirois, ... Lipids in health and disease 12 (1), 70, 2013 | 74 | 2013 |
| The proteomic landscape of the suprachiasmatic nucleus clock reveals large-scale coordination of key biological processes CK Chiang, N Mehta, A Patel, P Zhang, Z Ning, J Mayne, WYL Sun, ... PLoS genetics 10 (10), e1004695, 2014 | 71 | 2014 |
| RapidAIM: A culture-and metaproteomics-based Rapid Assay of Individual Microbiome responses to drugs L Li, Z Ning, X Zhang, J Mayne, K Cheng, A Stintzi, D Figeys bioRxiv, 543256, 2019 | 65 | 2019 |
| Annexin A2 reduces PCSK9 protein levels via a translational mechanism and interacts with the M1 and M2 domains of PCSK9 K Ly, YGL Saavedra, M Canuel, S Routhier, R Desjardins, J Hamelin, ... Journal of Biological Chemistry 289 (25), 17732-17746, 2014 | 56 | 2014 |
| Chronic kidney disease on hemodialysis is associated with decreased serum PCSK9 levels H Abujrad, J Mayne, M Ruzicka, M Cousins, A Raymond, J Cheesman, ... Atherosclerosis 233 (1), 123-129, 2014 | 55 | 2014 |
| Evaluating in Vitro Culture Medium of Gut Microbiome with Orthogonal Experimental Design and a Metaproteomics Approach L Li, X Zhang, Z Ning, J Mayne, JI Moore, J Butcher, CK Chiang, D Mack, ... Journal of proteome research 17 (1), 154-163, 2017 | 53 | 2017 |
Daniel FigeysUniversity of OttawaVerified email at uottawa.ca
