Marc Kirschner
Marc Kirschner
Professor of Systems Biology, Harvard Medical School
Verified email at hms.harvard.edu
TitleCited byYear
Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.
DW Cleveland, SG Fischer, MW Kirschner, UK Laemmli
Journal of Biological Chemistry 252 (3), 1102-1106, 1977
54321977
Dynamic instability of microtubule growth
T Mitchison, M Kirschner
nature 312 (5991), 237, 1984
30951984
A protein factor essential for microtubule assembly
MD Weingarten, AH Lockwood, SY Hwo, MW Kirschner
Proceedings of the National Academy of Sciences 72 (5), 1858-1862, 1975
26591975
Cyclin is degraded by the ubiquitin pathway
M Glotzer, AW Murray, MW Kirschner
Nature 349 (6305), 132, 1991
25581991
Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS
SA Gerber, J Rush, O Stemman, MW Kirschner, SP Gygi
Proceedings of the National Academy of Sciences 100 (12), 6940-6945, 2003
19222003
Number and evolutionary conservation of α-and β-tubulin and cytoplasmic β-and γ-actin genes using specific cloned cDNA probes
DW Cleveland, MA Lopata, RJ MacDonald, NJ Cowan, WJ Rutter, ...
Cell 20 (1), 95-105, 1980
17771980
A major developmental transition in early Xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage
J Newport, M Kirschner
Cell 30 (3), 675-686, 1982
16041982
Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis
S Kothakota, T Azuma, C Reinhard, A Klippel, J Tang, K Chu, TJ McGarry, ...
Science 278 (5336), 294-298, 1997
14671997
How proteolysis drives the cell cycle
RW King, RJ Deshaies, JM Peters, MW Kirschner
Science 274 (5293), 1652-1659, 1996
14551996
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
SMA Huang, YM Mishina, S Liu, A Cheung, F Stegmeier, GA Michaud, ...
Nature 461 (7264), 614, 2009
14512009
The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly
R Rohatgi, L Ma, H Miki, M Lopez, T Kirchhausen, T Takenawa, ...
Cell 97 (2), 221-231, 1999
13911999
Beyond self-assembly: from microtubules to morphogenesis
M Kirschner, T Mitchison
Cell 45 (3), 329-342, 1986
13541986
Evolvability
M Kirschner, J Gerhart
Proceedings of the National Academy of Sciences 95 (15), 8420-8427, 1998
13501998
Cyclin synthesis drives the early embryonic cell cycle
AW Murray, MW Kirschner
Nature 339 (6222), 275, 1989
12631989
Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells
AM Klein, L Mazutis, I Akartuna, N Tallapragada, A Veres, V Li, L Peshkin, ...
Cell 161 (5), 1187-1201, 2015
12212015
Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos
E Amaya, TJ Musci, MW Kirschner
Cell 66 (2), 257-270, 1991
12121991
The role of cyclin synthesis and degradation in the control of maturation promoting factor activity
AW Murray, MJ Solomon, MW Kirschner
Nature 339 (6222), 280, 1989
11761989
Cells, embryos, and evolution: Toward a cellular and developmental understanding of phenotypic variation and evolutionary adaptability
J Gerhart, M Kirschner
Blackwell Science, 1997
10711997
A major developmental transition in early Xenopus embryos: II. Control of the onset of transcription
J Newport, M Kirschner
Cell 30 (3), 687-696, 1982
10301982
A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B
RW King, JM Peters, S Tugendreich, M Rolfe, P Hieter, MW Kirschner
Cell 81 (2), 279-288, 1995
9891995
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Articles 1–20