Follow
Phil Jeffrey
Phil Jeffrey
Verified email at princeton.edu - Homepage
Title
Cited by
Cited by
Year
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations
Y Cho, S Gorina, PD Jeffrey, NP Pavletich
Science 265 (5170), 346-355, 1994
32961994
Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex
PD Jeffrey, AA Russo, K Polyak, E Gibbs, J Hurwitz, J Massagué, ...
Nature 376 (6538), 313-320, 1995
19051995
Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex
N Zheng, BA Schulman, L Song, JJ Miller, PD Jeffrey, P Wang, C Chu, ...
Nature 416 (6882), 703-709, 2002
17332002
Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
S Li, KR Schmitz, PD Jeffrey, JJW Wiltzius, P Kussie, KM Ferguson
Cancer cell 7 (4), 301-311, 2005
13252005
Crystal structure of the p27Kip1 cyclin-dependent-kinase inibitor bound to the cyclin A–Cdk2 complex
AA Russo, PD Jeffrey, AK Patten, J Massagué, NP Pavletich
Nature 382 (6589), 325-331, 1996
12181996
Structure of a c-Cbl–UbcH7 complex: RING domain function in ubiquitin-protein ligases
N Zheng, P Wang, PD Jeffrey, NP Pavletich
Cell 102 (4), 533-539, 2000
10762000
Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation
CR Antonescu, P Besmer, T Guo, K Arkun, G Hom, B Koryotowski, ...
Clinical cancer research 11 (11), 4182-4190, 2005
9672005
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
H Yang, PD Jeffrey, J Miller, E Kinnucan, Y Sun, NH Thoma, N Zheng, ...
Science 297 (5588), 1837-1848, 2002
8602002
Structural basis of cyclin-dependent kinase activation by phosphorylation
AA Russo, PD Jeffrey, NP Pavletich
Nature structural biology 3 (8), 696-700, 1996
8341996
Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms
PD Jeffrey, S Gorina, NP Pavletich
Science 267 (5203), 1498-1502, 1995
7851995
Insights into SCF ubiquitin ligases from the structure of the Skp1–Skp2 complex
BA Schulman, AC Carrano, PD Jeffrey, Z Bowen, ERE Kinnucan, ...
Nature 408 (6810), 381-386, 2000
7532000
Structure of a β-TrCP1-Skp1-β-catenin complex: destruction motif binding and lysine specificity of the SCFβ-TrCP1 ubiquitin ligase
G Wu, G Xu, BA Schulman, PD Jeffrey, JW Harper, NP Pavletich
Molecular cell 11 (6), 1445-1456, 2003
7422003
Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein
A Oberstein, PD Jeffrey, Y Shi
Journal of Biological Chemistry 282 (17), 13123-13132, 2007
6892007
Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a
AA Russo, L Tong, JO Lee, PD Jeffrey, NP Pavletich
Nature 395 (6699), 237-243, 1998
6711998
Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms
Y Xu, L Feng, PD Jeffrey, Y Shi, FMM Morel
Nature 452 (7183), 56-61, 2008
6232008
Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling
JP Himanen, MJ Chumley, M Lackmann, C Li, WA Barton, PD Jeffrey, ...
Nature neuroscience 7 (5), 501-509, 2004
5852004
Structure of the protein phosphatase 2A holoenzyme
Y Xu, Y Xing, Y Chen, Y Chao, Z Lin, E Fan, WY Jong, S Strack, ...
Cell 127 (6), 1239-1251, 2006
5762006
BET inhibitor resistance emerges from leukaemia stem cells
CY Fong, O Gilan, EYN Lam, AF Rubin, S Ftouni, D Tyler, K Stanley, ...
Nature 525 (7570), 538-542, 2015
5072015
Structural basis of UV DNA-damage recognition by the DDB1–DDB2 complex
A Scrima, R Koníčková, BK Czyzewski, Y Kawasaki, PD Jeffrey, ...
Cell 135 (7), 1213-1223, 2008
4852008
Structure and mechanisms of the proteasome‐associated deubiquitinating enzyme USP14
M Hu, P Li, L Song, PD Jeffrey, TA Chernova, KD Wilkinson, RE Cohen, ...
The EMBO journal 24 (21), 3747-3756, 2005
4832005
The system can't perform the operation now. Try again later.
Articles 1–20