| The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models MaQC Consortium Nature biotechnology 28 (8), 827, 2010 | 684 | 2010 |
| Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice GP Lahvis, SL Lindell, RS Thomas, RS McCuskey, C Murphy, E Glover, ... Proceedings of the National Academy of Sciences 97 (19), 10442-10447, 2000 | 414 | 2000 |
| Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment BA Wetmore, JF Wambaugh, SS Ferguson, MA Sochaski, DM Rotroff, ... Toxicological Sciences 125 (1), 157-174, 2012 | 314 | 2012 |
| ToxCast chemical landscape: paving the road to 21st century toxicology AM Richard, RS Judson, KA Houck, CM Grulke, P Volarath, ... Chemical research in toxicology 29 (8), 1225-1251, 2016 | 281 | 2016 |
| Identification of toxicologically predictive gene sets using cDNA microarrays RS Thomas, DR Rank, SG Penn, GM Zastrow, KR Hayes, K Pande, ... Molecular Pharmacology 60 (6), 1189-1194, 2001 | 273 | 2001 |
| A comparison of batch effect removal methods for enhancement of prediction performance using MAQC-II microarray gene expression data J Luo, M Schumacher, A Scherer, D Sanoudou, D Megherbi, T Davison, ... The pharmacogenomics journal 10 (4), 278-291, 2010 | 254 | 2010 |
| Incorporating Human Dosimetry and Exposure into High-Throughput In Vitro Toxicity Screening DM Rotroff, BA Wetmore, DJ Dix, SS Ferguson, HJ Clewell, KA Houck, ... Toxicological Sciences 117 (2), 348-358, 2010 | 219 | 2010 |
| Incorporating new technologies into toxicity testing and risk assessment: moving from 21st century vision to a data-driven framework RS Thomas, MA Philbert, SS Auerbach, BA Wetmore, MJ Devito, I Cote, ... toxicological sciences 136 (1), 4-18, 2013 | 192 | 2013 |
| Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor RS Judson, FM Magpantay, V Chickarmane, C Haskell, N Tania, J Taylor, ... Toxicological Sciences 148 (1), 137-154, 2015 | 186 | 2015 |
| Estimating toxicity-related biological pathway altering doses for high-throughput chemical risk assessment RS Judson, RJ Kavlock, RW Setzer, EA Cohen Hubal, MT Martin, ... Chemical research in toxicology 24 (4), 451-462, 2011 | 185 | 2011 |
| Screening chemicals for estrogen receptor bioactivity using a computational model P Browne, RS Judson, WM Casey, NC Kleinstreuer, RS Thomas Environmental science & technology 49 (14), 8804-8814, 2015 | 172 | 2015 |
| Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing BA Wetmore, JF Wambaugh, B Allen, SS Ferguson, MA Sochaski, ... Toxicological Sciences 148 (1), 121-136, 2015 | 169 | 2015 |
| A method to integrate benchmark dose estimates with genomic data to assess the functional effects of chemical exposure RS Thomas, BC Allen, A Nong, L Yang, E Bermudez, HJ Clewell III, ... Toxicological sciences 98 (1), 240-248, 2007 | 152 | 2007 |
| IVT-seq reveals extreme bias in RNA sequencing NF Lahens, IH Kavakli, R Zhang, K Hayer, MB Black, H Dueck, A Pizarro, ... Genome biology 15 (6), R86, 2014 | 144 | 2014 |
| BMDExpress: a software tool for the benchmark dose analyses of genomic data L Yang, BC Allen, RS Thomas BMC genomics 8 (1), 387, 2007 | 140 | 2007 |
| Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space R Judson, K Houck, M Martin, AM Richard, TB Knudsen, I Shah, S Little, ... Toxicological Sciences 152 (2), 323-339, 2016 | 137 | 2016 |
| A Comprehensive Statistical Analysis of Predicting In Vivo Hazard Using High-Throughput In Vitro Screening RS Thomas, MB Black, L Li, E Healy, TM Chu, W Bao, ME Andersen, ... Toxicological Sciences 128 (2), 398-417, 2012 | 136 | 2012 |
| Genome-wide analysis of human HSF1 signaling reveals a transcriptional program linked to cellular adaptation and survival TJ Page, D Sikder, L Yang, L Pluta, RD Wolfinger, T Kodadek, ... Molecular bioSystems 2 (12), 627-639, 2006 | 135 | 2006 |
| Activation of the aryl-hydrocarbon receptor inhibits invasive and metastatic features of human breast cancer cells and promotes breast cancer cell differentiation JM Hall, MA Barhoover, D Kazmin, DP McDonnell, WF Greenlee, ... Molecular endocrinology 24 (2), 359-369, 2010 | 132 | 2010 |
| Aryl hydrocarbon receptor regulates cell cycle progression in human breast cancer cells via a functional interaction with cyclin-dependent kinase 4 MA Barhoover, JM Hall, WF Greenlee, RS Thomas Molecular pharmacology 77 (2), 195-201, 2010 | 126 | 2010 |
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