Cdk5 disruption attenuates tumor PD-L1 expression and promotes antitumor immunity AP Dixon Dorand, Joseph Nthale, Jay T. Myers, Deborah S. Barkauskas ... Science 353 (6297), 399-403, 2016 | 309 | 2016 |
Cyclin-dependent kinase 5 activity regulates pain signaling TK Pareek, J Keller, S Kesavapany, HC Pant, MJ Iadarola, RO Brady, ... Proceedings of the National Academy of Sciences 103 (3), 791-796, 2006 | 171 | 2006 |
Cyclin-dependent kinase 5 modulates nociceptive signaling through direct phosphorylation of transient receptor potential vanilloid 1 TK Pareek, J Keller, S Kesavapany, N Agarwal, R Kuner, HC Pant, ... Proceedings of the National Academy of Sciences 104 (2), 660-665, 2007 | 131 | 2007 |
Cdk5/p25-induced cytosolic PLA2-mediated lysophosphatidylcholine production regulates neuroinflammation and triggers neurodegeneration JR Sundaram, ES Chan, CP Poore, TK Pareek, WF Cheong, G Shui, ... Journal of Neuroscience 32 (3), 1020-1034, 2012 | 126 | 2012 |
Triterpenoid modulation of IL-17 and Nrf-2 expression ameliorates neuroinflammation and promotes remyelination in autoimmune encephalomyelitis TK Pareek, A Belkadi, S Kesavapany, A Zaremba, SL Loh, L Bai, ... Scientific reports 1 (1), 201, 2011 | 121 | 2011 |
Specific inhibition of p25/Cdk5 activity by the Cdk5 inhibitory peptide reduces neurodegeneration in vivo JR Sundaram, CP Poore, NHB Sulaimee, T Pareek, A Asad, R Rajkumar, ... Journal of Neuroscience 33 (1), 334-343, 2013 | 102 | 2013 |
Insights into male germ cell apoptosis due to depletion of gonadotropins caused by GnRH antagonists TK Pareek, AR Joshi, A Sanyal, RR Dighe Apoptosis 12, 1085-1100, 2007 | 94 | 2007 |
Curcumin ameliorates neuroinflammation, neurodegeneration, and memory deficits in p25 transgenic mouse model that bears hallmarks of Alzheimer’s disease JR Sundaram, CP Poore, NHB Sulaimee, T Pareek, WF Cheong, ... Journal of Alzheimer's Disease 60 (4), 1429-1442, 2017 | 88 | 2017 |
Cdk5: a new player in pain signaling TK Pareek, AB Kulkarni Cell cycle 5 (6), 585-588, 2006 | 85 | 2006 |
Cyclin-dependent kinase 5 activity is required for T cell activation and induction of experimental autoimmune encephalomyelitis TK Pareek, E Lam, X Zheng, D Askew, AB Kulkarni, MR Chance, ... Journal of Experimental Medicine 207 (11), 2507-2519, 2010 | 77 | 2010 |
Inhibition of Pin1 reduces glutamate-induced perikaryal accumulation of phosphorylated neurofilament-H in neurons S Kesavapany, V Patel, YL Zheng, TK Pareek, M Bjelogrlic, W Albers, ... Molecular biology of the cell 18 (9), 3645-3655, 2007 | 71 | 2007 |
Conditional deletion of neuronal cyclin-dependent kinase 5 in developing forebrain results in microglial activation and neurodegeneration S Takahashi, T Ohshima, M Hirasawa, TK Pareek, TH Bugge, A Morozov, ... The American journal of pathology 176 (1), 320-329, 2010 | 47 | 2010 |
Phosphorylation of p27Kip1 at Thr187 by Cyclin-dependent Kinase 5 Modulates Neural Stem Cell Differentiation YL Zheng, BS Li, P Rudrabhatla, V Shukla, ND Amin, D Maric, ... Molecular biology of the cell 21 (20), 3601-3614, 2010 | 44 | 2010 |
Molecular roles of Cdk5 in pain signaling E Utreras, A Futatsugi, TK Pareek, AB Kulkarni Drug Discovery Today: Therapeutic Strategies 6 (3), 105-111, 2009 | 43 | 2009 |
Cdk5-mediated phosphorylation of δ-catenin regulates its localization and GluR2-mediated synaptic activity CP Poore, JR Sundaram, TK Pareek, A Fu, N Amin, NE Mohamed, ... Journal of Neuroscience 30 (25), 8457-8467, 2010 | 36 | 2010 |
Neurofilament tail phosphorylation: identity of the RT‐97 phosphoepitope and regulation in neurons by cross‐talk among proline‐directed kinases Veeranna, JH Lee, TK Pareek, H Jaffee, B Boland, KY Vinod, N Amin, ... Journal of neurochemistry 107 (1), 35-49, 2008 | 34 | 2008 |
Nrf2-mediated metabolic reprogramming of tolerogenic dendritic cells is protective against aplastic anemia HJ Wei, A Gupta, WM Kao, O Almudallal, JJ Letterio, TK Pareek Journal of Autoimmunity 94, 33-44, 2018 | 30 | 2018 |
Cyclin-dependent kinase 5 represses Foxp3 gene expression and Treg development through specific phosphorylation of Stat3 at Serine 727 E Lam, SH Choi, TK Pareek, BG Kim, JJ Letterio Molecular immunology 67 (2), 317-324, 2015 | 30 | 2015 |
Neuronal nuclear organization is controlled by cyclin-dependent kinase 5 phosphorylation of Ras Guanine nucleotide releasing factor-1 S Kesavapany, TK Pareek, YL Zheng, N Amin, JS Gutkind, W Ma, ... Neurosignals 15 (4), 157-173, 2007 | 29 | 2007 |
Cdk5 controls IL-2 gene expression via repression of the mSin3a-HDAC complex E Lam, TK Pareek, JJ Letterio Cell cycle 14 (8), 1327-1336, 2015 | 26 | 2015 |