Spatial transcriptomics of dorsal root ganglia identifies molecular signatures of human nociceptors D Tavares-Ferreira, S Shiers, PR Ray, A Wangzhou, V Jeevakumar, ... Science translational medicine 14 (632), eabj8186, 2022 | 187 | 2022 |
Quantitative differences in neuronal subpopulations between mouse and human dorsal root ganglia demonstrated with RNAscope in situ hybridization S Shiers, RM Klein, TJ Price Pain 161 (10), 2410-2424, 2020 | 146 | 2020 |
Studying human nociceptors: from fundamentals to clinic SJ Middleton, AM Barry, M Comini, Y Li, PR Ray, S Shiers, ... Brain 144 (5), 1312-1335, 2021 | 104 | 2021 |
Neurobiology of SARS-CoV-2 interactions with the peripheral nervous system: implications for COVID-19 and pain AJ McFarland, MS Yousuf, S Shiers, TJ Price Pain reports 6 (1), e885, 2021 | 100 | 2021 |
ACE2 and SCARF expression in human dorsal root ganglion nociceptors: implications for SARS-CoV-2 virus neurological effects S Shiers, PR Ray, A Wangzhou, I Sankaranarayanan, CE Tatsui, ... Pain 161 (11), 2494-2501, 2020 | 94 | 2020 |
A critical role for dopamine D5 receptors in pain chronicity in male mice S Megat, S Shiers, JK Moy, P Barragan-Iglesias, G Pradhan, RP Seal, ... Journal of Neuroscience 38 (2), 379-397, 2018 | 82 | 2018 |
Neuropathic pain creates an enduring prefrontal cortex dysfunction corrected by the type II diabetic drug metformin but not by gabapentin S Shiers, G Pradhan, J Mwirigi, G Mejia, A Ahmad, S Kroener, T Price Journal of Neuroscience 38 (33), 7337-7350, 2018 | 77 | 2018 |
Pharmacological target-focused transcriptomic analysis of native vs cultured human and mouse dorsal root ganglia A Wangzhou, LA McIlvried, C Paige, P Barragan-Iglesias, S Shiers, ... Pain 161 (7), 1497-1517, 2020 | 73 | 2020 |
Convergence of peptidergic and non‐peptidergic protein markers in the human dorsal root ganglion and spinal dorsal horn SI Shiers, I Sankaranarayanan, V Jeevakumar, A Cervantes, JC Reese, ... Journal of Comparative Neurology 529 (10), 2771-2788, 2021 | 71 | 2021 |
Type I interferons act directly on nociceptors to produce pain sensitization: implications for viral infection-induced pain P Barragán-Iglesias, Ú Franco-Enzástiga, V Jeevakumar, S Shiers, ... Journal of Neuroscience 40 (18), 3517-3532, 2020 | 68 | 2020 |
The CysLT2R receptor mediates leukotriene C4-driven acute and chronic itch T Voisin, C Perner, MA Messou, S Shiers, S Ualiyeva, Y Kanaoka, ... Proceedings of the National Academy of Sciences 118 (13), e2022087118, 2021 | 63 | 2021 |
RNA profiling of human dorsal root ganglia reveals sex differences in mechanisms promoting neuropathic pain PR Ray, S Shiers, JP Caruso, D Tavares-Ferreira, I Sankaranarayanan, ... Brain 146 (2), 749-766, 2023 | 54 | 2023 |
Transient receptor potential canonical 5 mediates inflammatory mechanical and spontaneous pain in mice KE Sadler, F Moehring, SI Shiers, LJ Laskowski, AR Mikesell, ZR Plautz, ... Science translational medicine 13 (595), eabd7702, 2021 | 50 | 2021 |
Sex differences in nociceptor translatomes contribute to divergent prostaglandin signaling in male and female mice D Tavares-Ferreira, PR Ray, I Sankaranarayanan, GL Mejia, A Wangzhou, ... Biological psychiatry 91 (1), 129-140, 2022 | 47 | 2022 |
Reversal of peripheral nerve injury-induced neuropathic pain and cognitive dysfunction via genetic and tomivosertib targeting of MNK S Shiers, J Mwirigi, G Pradhan, M Kume, B Black, P Barragan-Iglesias, ... Neuropsychopharmacology 45 (3), 524-533, 2020 | 45 | 2020 |
Transcriptomic analysis of human sensory neurons in painful diabetic neuropathy reveals inflammation and neuronal loss BE Hall, E Macdonald, M Cassidy, S Yun, MR Sapio, P Ray, M Doty, ... Scientific reports 12 (1), 4729, 2022 | 42 | 2022 |
A pharmacological interactome between COVID-19 patient samples and human sensory neurons reveals potential drivers of neurogenic pulmonary dysfunction PR Ray, A Wangzhou, N Ghneim, MS Yousuf, C Paige, ... Brain, behavior, and immunity 89, 559-568, 2020 | 42 | 2020 |
Pharmacological manipulation of translation as a therapeutic target for chronic pain MS Yousuf, SI Shiers, JJ Sahn, TJ Price Pharmacological reviews 73 (1), 59-88, 2021 | 37 | 2021 |
The cellular basis of protease-activated receptor 2–evoked mechanical and affective pain SN Hassler, M Kume, JM Mwirigi, A Ahmad, S Shiers, A Wangzhou, ... JCI insight 5 (11), 2020 | 25 | 2020 |
Spatial transcriptomics reveals unique molecular fingerprints of human nociceptors D Tavares-Ferreira, S Shiers, PR Ray, A Wangzhou, V Jeevakumar, ... BiorXiv, 2021.02. 06.430065, 2021 | 24 | 2021 |