| Neurofibrillary tangles in Alzheimer's disease: elucidation of the molecular mechanism by immunohistochemistry and tau protein phospho-proteomics A Metaxas, SJ Kempf Neural regeneration research 11 (10), 1579-1581, 2016 | 135 | 2016 |
| Decrease of D2 receptor binding but increase in D2‐stimulated G‐protein activation, dopamine transporter binding and behavioural sensitization in brains of mice … A Bailey, A Metaxas, JH Yoo, T McGee, I Kitchen European Journal of Neuroscience 28 (4), 759-770, 2008 | 60 | 2008 |
| In vivo detection of amyloid-β deposits using heavy chain antibody fragments in a transgenic mouse model for Alzheimer's disease RJA Nabuurs, KS Rutgers, MM Welling, A Metaxas, ME De Backer, ... PLoS One 7 (6), e38284, 2012 | 53 | 2012 |
| Differential region‐specific regulation of α4β2* nAChRs by self‐administered and non‐contingent nicotine in C57BL/6J mice A Metaxas, A Bailey, MF Barbano, L Galeote, R Maldonado, I Kitchen Addiction biology 15 (4), 464-479, 2010 | 45 | 2010 |
| An integrated proteomics approach shows synaptic plasticity changes in an APP/PS1 Alzheimer's mouse model SJ Kempf, A Metaxas, M Ibáñez-Vea, S Darvesh, B Finsen, MR Larsen Oncotarget 7 (23), 33627, 2016 | 44 | 2016 |
| Mouse strain differences in locomotor, sensitisation and rewarding effect of heroin; association with alterations in MOP‐r activation and dopamine transporter binding A Bailey, A Metaxas, R Al‐Hasani, HL Keyworth, DM Forster, I Kitchen European Journal of Neuroscience 31 (4), 742-753, 2010 | 39 | 2010 |
| Effect of aging and Alzheimer's disease-like pathology on brain monoamines in mice CU Von Linstow, M Severino, A Metaxas, J Waider, AA Babcock, ... Neurochemistry International 108, 238-245, 2017 | 38 | 2017 |
| Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer’s disease A Metaxas, C Thygesen, SJ Kempf, M Anzalone, R Vaitheeswaran, ... Scientific Reports 9 (1), 15758, 2019 | 27 | 2019 |
| Region-specific up-regulation of oxytocin receptor binding in the brain of mice following chronic nicotine administration P Zanos, P Georgiou, A Metaxas, I Kitchen, R Winsky-Sommerer, A Bailey Neuroscience Letters 600, 33-37, 2015 | 27 | 2015 |
| Increased inflammation and unchanged density of synaptic vesicle glycoprotein 2A (SV2A) in the postmortem frontal cortex of Alzheimer’s disease patients A Metaxas, C Thygesen, SRR Briting, AM Landau, S Darvesh, B Finsen Frontiers in cellular neuroscience 13, 538, 2019 | 25 | 2019 |
| Structure–activity relationships of N-substituted 4-(trifluoromethoxy) benzamidines with affinity for GluN2B-containing NMDA receptors C Beinat, SD Banister, J Hoban, J Tsanaktsidis, A Metaxas, AD Windhorst, ... Bioorganic & Medicinal Chemistry Letters 24 (3), 828-830, 2014 | 24 | 2014 |
| Quantification of the novel N-methyl-d-aspartate receptor ligand [11C]GMOM in man TF van der Doef, SSV Golla, PJ Klein, GM Oropeza-Seguias, RC Schuit, ... Journal of Cerebral Blood Flow & Metabolism 36 (6), 1111-1121, 2016 | 23 | 2016 |
| Neuroinflammation and amyloid-beta 40 are associated with reduced serotonin transporter (SERT) activity in a transgenic model of familial Alzheimer’s disease A Metaxas, M Anzalone, R Vaitheeswaran, S Petersen, AM Landau, ... Alzheimer's research & therapy 11, 1-13, 2019 | 22 | 2019 |
| Preclinical evaluation of [18F] PK-209, a new PET ligand for imaging the ion-channel site of NMDA receptors SSV Golla, PJ Klein, J Bakker, RC Schuit, JAM Christiaans, L van Geest, ... Nuclear medicine and biology 42 (2), 205-212, 2015 | 21 | 2015 |
| Polyfluorinated bis-styrylbenzenes as amyloid-β plaque binding ligands RJA Nabuurs, VV Kapoerchan, A Metaxas, S de Jongh, M de Backer, ... Bioorganic & Medicinal Chemistry 22 (8), 2469-2481, 2014 | 21 | 2014 |
| Established amyloid-β pathology is unaffected by chronic treatment with the selective serotonin reuptake inhibitor paroxetine M Severino, M Sivasaravanaparan, LØ Olesen, CU von Linstow, ... Alzheimer's & Dementia: Translational Research & Clinical Interventions 4 …, 2018 | 20 | 2018 |
| Serotonin augmentation therapy by escitalopram has minimal effects on amyloid-β levels in early-stage Alzheimer’s-like disease in mice CU von Linstow, J Waider, M Grebing, A Metaxas, KP Lesch, B Finsen Alzheimer's Research & Therapy 9, 1-12, 2017 | 20 | 2017 |
| Synthesis, structure activity relationship, radiolabeling and preclinical evaluation of high affinity ligands for the ion channel of the N-methyl-d-aspartate receptor as … PJ Klein, JAM Christiaans, A Metaxas, RC Schuit, AA Lammertsma, ... Bioorganic & Medicinal Chemistry 23 (5), 1189-1206, 2015 | 20 | 2015 |
| Synthesis, radiolabeling and evaluation of novel amine guanidine derivatives as potential positron emission tomography tracers for the ion channel of the N-methyl-d-aspartate … PJ Klein, M Chomet, A Metaxas, JAM Christiaans, E Kooijman, RC Schuit, ... European journal of medicinal chemistry 118, 143-160, 2016 | 17 | 2016 |
| The stereotypy‐inducing and OCD‐like effects of chronic ‘binge’cocaine are modulated by distinct subtypes of nicotinic acetylcholine receptors A Metaxas, HL Keyworth, JH Yoo, Y Chen, I Kitchen, A Bailey British journal of pharmacology 167 (2), 450-464, 2012 | 17 | 2012 |
Bart van BerckelProfessor of Molecular Brain Imaging, Amsterdam University Medical CenterVerified email at VUmc.nl
