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Ajeeth Pingili
Ajeeth Pingili
Takeda
Verified email at Takeda.com
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Year
Myeloid Slc2a1-deficient murine model revealed macrophage activation and metabolic phenotype are fueled by GLUT1
AJ Freemerman, L Zhao, AK Pingili, B Teng, AJ Cozzo, AM Fuller, ...
The Journal of Immunology 202 (4), 1265-1286, 2019
1112019
Estrogen metabolism by cytochrome P450 1B1 modulates the hypertensive effect of angiotensin II in female mice
BL Jennings, LW George, AK Pingili, NS Khan, AM Estes, XR Fang, ...
Hypertension 64 (1), 134-140, 2014
622014
Microbiome, bile acids, and obesity: How microbially modified metabolites shape anti‐tumor immunity
LM Sipe, M Chaib, AK Pingili, JF Pierre, L Makowski
Immunological Reviews 295 (1), 220-239, 2020
502020
Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer
AK Pingili, M Chaib, LM Sipe, EJ Miller, B Teng, R Sharma, JR Yarbro, ...
Cell reports 35 (12), 2021
492021
6β-Hydroxytestosterone, a cytochrome P450 1B1 metabolite of testosterone, contributes to angiotensin II–induced hypertension and its pathogenesis in male mice
AK Pingili, M Kara, NS Khan, AM Estes, Z Lin, W Li, FJ Gonzalez, ...
Hypertension 65 (6), 1279-1287, 2015
472015
Pressor effect of apelin-13 in the rostral ventrolateral medulla: role of NAD (P) H oxidase-derived superoxide
F Yao, A Modgil, Q Zhang, A Pingili, N Singh, ST O'Rourke, C Sun
Journal of Pharmacology and Experimental Therapeutics 336 (2), 372-380, 2011
362011
2-Methoxyestradiol reduces angiotensin II–induced hypertension and renal dysfunction in ovariectomized female and intact male mice
AK Pingili, KN Davidge, S Thirunavukkarasu, NS Khan, A Katsurada, ...
Hypertension 69 (6), 1104-1112, 2017
272017
Role of TGF-β in pancreatic ductal adenocarcinoma progression and PD-L1 expression
SM Hussain, RG Kansal, MA Alvarez, TJ Hollingsworth, A Elahi, ...
Cellular Oncology 44, 673-687, 2021
242021
6β-Hydroxytestosterone, a Cytochrome P450 1B1-Testosterone–Metabolite, Mediates Angiotensin II–Induced Renal Dysfunction in Male Mice
AK Pingili, S Thirunavukkarasu, M Kara, DD Brand, A Katsurada, ...
Hypertension 67 (5), 916-926, 2016
232016
Angiotensin-(1–7) attenuates the chronotropic response to angiotensin II via stimulation of PTEN in the spontaneously hypertensive rat neurons
A Modgil, Q Zhang, A Pingili, N Singh, F Yao, J Ge, L Guo, C Xuan, ...
American Journal of Physiology-Heart and Circulatory Physiology 302 (5 …, 2012
212012
6β-Hydroxytestosterone, a metabolite of testosterone generated by CYP1B1, contributes to vascular changes in angiotensin II-induced hypertension in male mice
AK Pingili, BL Jennings, K Mukherjee, W Akroush, FJ Gonzalez, KU Malik
Biology of sex Differences 11, 1-15, 2020
152020
TGF-β alters the proportion of infiltrating immune cells in a pancreatic ductal adenocarcinoma
K Trebska-McGowan, M Chaib, MA Alvarez, R Kansal, AK Pingili, ...
Journal of Gastrointestinal Surgery 26 (1), 113-121, 2022
142022
Disruption of the cytochrome P-450 1B1 gene exacerbates renal dysfunction and damage associated with angiotensin II-induced hypertension in female mice
BL Jennings, JA Moore, AK Pingili, AM Estes, XR Fang, A Kanu, ...
American Journal of Physiology-Renal Physiology 308 (9), F981-F992, 2015
132015
Response to immune checkpoint blockade improved in pre-clinical model of breast cancer after bariatric surgery
LM Sipe, M Chaib, EB Korba, H Jo, MC Lovely, BR Counts, U Tanveer, ...
Elife 11, e79143, 2022
122022
PKC agonism restricts innate immune suppression, promotes antigen cross-presentation and synergizes with agonistic CD40 antibody therapy to activate CD8+ T cells in breast cancer
M Chaib, LM Sipe, JR Yarbro, MS Bohm, BR Counts, U Tanveer, ...
Cancer letters 531, 98-108, 2022
82022
Reprogramming of pancreatic adenocarcinoma immunosurveillance by a microbial probiotic siderophore
M Chaib, BB Hafeez, H Mandil, D Daria, AK Pingili, S Kumari, M Sikander, ...
Communications Biology 5 (1), 1181, 2022
62022
Testosterone Metabolite 6β‐Hydroxytestosterone Contributes to Angiotensin II‐Induced Abdominal Aortic Aneurysms in Apoe–/– Male Mice
K Mukherjee, AK Pingili, P Singh, AN Dhodi, SR Dutta, FJ Gonzalez, ...
Journal of the American Heart Association 10 (7), e018536, 2021
62021
6β-Hydroxytestosterone Promotes Angiotensin II-Induced Hypertension via Enhanced Cytosolic Phospholipase A2α Activity
P Singh, CY Song, SR Dutta, A Pingili, JS Shin, FJ Gonzalez, ...
Hypertension 78 (4), 1053-1066, 2021
12021
Myeloid PKCd activation inhibits innate immune suppression and promotes antigen cross-presentation in triple negative breast cancer
M Chaib, J Holt, L Sipe, A Pingili, TJ Hollingsworth, D Daria, N Hayes, ...
Cancer Research 81 (13_Supplement), 118-118, 2021
12021
Intestinal fungi as regulators of obesity and glucose tolerance
Q Al Abdallah, T Mims, S Watts, A Pingili, A Bajwa, B Teng, L Makowski, ...
The FASEB Journal 34 (S1), 1-1, 2020
12020
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Articles 1–20