Comprehensive molecular portraits of human breast tumours Brigham & Women’s Hospital & Harvard Medical School Chin Lynda 9 11 Park ... Nature 490 (7418), 61-70, 2012 | 10067 | 2012 |
The immune landscape of cancer V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone, THO Yang, ... Immunity 48 (4), 812-830. e14, 2018 | 3233 | 2018 |
Oncogenic pathway signatures in human cancers as a guide to targeted therapies AH Bild, G Yao, JT Chang, Q Wang, A Potti, D Chasse, MB Joshi, ... Nature 439 (7074), 353-357, 2006 | 2268 | 2006 |
An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics J Liu, T Lichtenberg, KA Hoadley, LM Poisson, AJ Lazar, AD Cherniack, ... Cell 173 (2), 400-416. e11, 2018 | 1875 | 2018 |
Oncogenic signaling pathways in the cancer genome atlas F Sanchez-Vega, M Mina, J Armenia, WK Chatila, A Luna, KC La, ... Cell 173 (2), 321-337. e10, 2018 | 1851 | 2018 |
Comprehensive characterization of cancer driver genes and mutations MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ... Cell 173 (2), 371-385. e18, 2018 | 1745 | 2018 |
Predicting the clinical status of human breast cancer by using gene expression profiles M West, C Blanchette, H Dressman, E Huang, S Ishida, R Spang, H Zuzan, ... Proceedings of the National Academy of Sciences 98 (20), 11462-11467, 2001 | 1712 | 2001 |
BRCA1 Mutations in Primary Breast and Ovarian Carcinomas PA Futreal, Q Liu, D Shattuck-Eidens, C Cochran, K Harshman, ... Science 266 (5182), 120-122, 1994 | 1707 | 1994 |
Cell-of-origin patterns dominate the molecular classification of 10,000 tumors from 33 types of cancer KA Hoadley, C Yau, T Hinoue, DM Wolf, AJ Lazar, E Drill, R Shen, ... Cell 173 (2), 291-304. e6, 2018 | 1584 | 2018 |
Comprehensive molecular portraits of invasive lobular breast cancer G Ciriello, ML Gatza, AH Beck, MD Wilkerson, SK Rhie, A Pastore, ... Cell 163 (2), 506-519, 2015 | 1546 | 2015 |
Machine learning identifies stemness features associated with oncogenic dedifferentiation TM Malta, A Sokolov, AJ Gentles, T Burzykowski, L Poisson, JN Weinstein, ... Cell 173 (2), 338-354. e15, 2018 | 1065 | 2018 |
Young age at diagnosis correlates with worse prognosis and defines a subset of breast cancers with shared patterns of gene expression CK Anders, DS Hsu, G Broadwater, CR Acharya, JA Foekens, Y Zhang, ... Journal of clinical oncology 26 (20), 3324-3330, 2008 | 1001 | 2008 |
Genomic and molecular landscape of DNA damage repair deficiency across The Cancer Genome Atlas TA Knijnenburg, L Wang, MT Zimmermann, N Chambwe, GF Gao, ... Cell reports 23 (1), 239-254. e6, 2018 | 687 | 2018 |
The cancer genome atlas comprehensive molecular characterization of renal cell carcinoma CJ Ricketts, AA De Cubas, H Fan, CC Smith, M Lang, E Reznik, R Bowlby, ... Cell reports 23 (1), 313-326. e5, 2018 | 665 | 2018 |
Genomic and functional approaches to understanding cancer aneuploidy AM Taylor, J Shih, G Ha, GF Gao, X Zhang, AC Berger, SE Schumacher, ... Cancer cell 33 (4), 676-689. e3, 2018 | 661 | 2018 |
Genomic signatures to guide the use of chemotherapeutics A Potti, HK Dressman, A Bild, RF Riedel, G Chan, R Sayer, J Cragun, ... Nature medicine 12 (11), 1294-1300, 2006 | 653 | 2006 |
Spatial organization and molecular correlation of tumor-infiltrating lymphocytes using deep learning on pathology images J Saltz, R Gupta, L Hou, T Kurc, P Singh, V Nguyen, D Samaras, ... Cell reports 23 (1), 181-193. e7, 2018 | 628 | 2018 |
Overexpression and mutation of p53 in epithelial ovarian cancer JR Marks, AM Davidoff, BJ Kerns, PA Humphrey, JC Pence, RK Dodge, ... Cancer research 51 (11), 2979-2984, 1991 | 625 | 1991 |
Compromised HOXA5 function can limit p53 expression in human breast tumours V Raman, SA Martensen, D Reisman, E Evron, WF Odenwald, E Jaffee, ... Nature 405 (6789), 974-978, 2000 | 620 | 2000 |
Pathogenic germline variants in 10,389 adult cancers K Huang, RJ Mashl, Y Wu, DI Ritter, J Wang, C Oh, M Paczkowska, ... Cell 173 (2), 355-370. e14, 2018 | 587 | 2018 |