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Adam J Middleton
Adam J Middleton
Research Fellow, University of Otago
Verified email at otago.ac.nz
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Cited by
Cited by
Year
Antifreeze protein from freeze-tolerant grass has a beta-roll fold with an irregularly structured ice-binding site
AJ Middleton, CB Marshall, F Faucher, M Bar-Dolev, I Braslavsky, ...
Journal of molecular biology 416 (5), 713-724, 2012
1632012
Ice restructuring inhibition activities in antifreeze proteins with distinct differences in thermal hysteresis
OY Sally, A Brown, AJ Middleton, MM Tomczak, VK Walker, PL Davies
Cryobiology 61 (3), 327-334, 2010
1272010
Identification of the ice-binding face of a plant antifreeze protein
AJ Middleton, AM Brown, PL Davies, VK Walker
FEBS letters 583 (4), 815-819, 2009
1122009
Compound ice-binding site of an antifreeze protein revealed by mutagenesis and fluorescent tagging
CP Garnham, A Natarajan, AJ Middleton, MJ Kuiper, I Braslavsky, ...
Biochemistry 49 (42), 9063-9071, 2010
1052010
Expression and characterization of an antifreeze protein from the perennial rye grass, Lolium perenne
KJ Lauersen, A Brown, A Middleton, PL Davies, VK Walker
Cryobiology 62 (3), 194-201, 2011
632011
The molecular basis of lysine 48 ubiquitin chain synthesis by Ube2K
AJ Middleton, CL Day
Scientific reports 5 (1), 16793, 2015
562015
The activity of TRAF RING homo-and heterodimers is regulated by zinc finger 1
AJ Middleton, R Budhidarmo, A Das, J Zhu, M Foglizzo, PD Mace, CL Day
Nature communications 8 (1), 1788, 2017
432017
A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes
M Foglizzo, AJ Middleton, AE Burgess, JM Crowther, RCJ Dobson, ...
Nature Communications 9 (1), 3932, 2018
292018
Structure and function of the RING domains of RNF20 and RNF40, dimeric E3 ligases that monoubiquitylate histone H2B
M Foglizzo, AJ Middleton, CL Day
Journal of Molecular Biology 428 (20), 4073-4086, 2016
282016
Use of E2~ ubiquitin conjugates for the characterization of ubiquitin transfer by RING E3 ligases such as the inhibitor of apoptosis proteins
AJ Middleton, R Budhidarmo, CL Day
Methods in Enzymology 545, 243-263, 2014
252014
The structure and ubiquitin binding properties of TRAF RING heterodimers
A Das, AJ Middleton, P Padala, EC Ledgerwood, PD Mace, CL Day
Journal of Molecular Biology 433 (8), 166844, 2021
222021
Regulation of E2s: a role for additional ubiquitin binding sites?
AJ Middleton, JD Wright, CL Day
Journal of Molecular Biology 429 (22), 3430-3440, 2017
192017
Identification of ubiquitin variants that inhibit the E2 ubiquitin conjugating enzyme, Ube2k
AJ Middleton, J Teyra, J Zhu, SS Sidhu, CL Day
ACS chemical biology 16 (9), 1745-1756, 2021
152021
The RING domain of RING finger 12 efficiently builds degradative ubiquitin chains
AJ Middleton, J Zhu, CL Day
Journal of molecular biology 432 (13), 3790-3801, 2020
142020
Isolation and characterization of ice-binding proteins from higher plants
AJ Middleton, B Vanderbeld, M Bredow, H Tomalty, PL Davies, VK Walker
Plant Cold Acclimation: Methods and Protocols, 255-277, 2014
142014
The RING domain of RING Finger 11 (RNF 11) protein binds Ubc13 and inhibits formation of polyubiquitin chains
R Budhidarmo, J Zhu, AJ Middleton, CL Day
FEBS letters 592 (8), 1434-1444, 2018
112018
Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C
A Paluda, AJ Middleton, C Rossig, PD Mace, CL Day
Nature Communications 13 (1), 1181, 2022
92022
Genetically-engineered mutant antifreeze proteins provide insight into hydrate inhibition
D Myran, A Middleton, J Choi, R Gordienko, H Ohno, JA Ripmeester, ...
Proceedings of the 7th International Conference on Gas Hydrates, 17-21, 2011
82011
Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex
MR Groves, CFE Schroer, AJ Middleton, S Lunev, N Danda, AM Ali, ...
Biochemical and biophysical research communications 496 (2), 562-567, 2018
62018
Isolation and characterization of ice-binding proteins from higher plants
M Bredow, HE Tomalty, LA Graham, AK Gruneberg, AJ Middleton, ...
Plant Cold Acclimation: Methods and Protocols, 303-332, 2020
32020
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