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Robert Vander Velde
Robert Vander Velde
Sydney Shaffer Lab, University of Pennsylvania
Verified email at upenn.edu
Title
Cited by
Cited by
Year
Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures
R Vander Velde, N Yoon, V Marusyk, A Durmaz, A Dhawan, ...
Nature communications 11 (1), 2393, 2020
822020
Cancer treatment scheduling and dynamic heterogeneity in social dilemmas of tumour acidity and vasculature
A Kaznatcheev, R Vander Velde, JG Scott, D Basanta
British journal of cancer 116 (6), 785-792, 2017
602017
Spontaneous cell fusions as a mechanism of parasexual recombination in tumour cell populations
D Miroshnychenko, E Baratchart, MC Ferrall-Fairbanks, RV Velde, ...
Nature Ecology & Evolution 5 (3), 379-391, 2021
512021
Optimal therapy scheduling based on a pair of collaterally sensitive drugs
N Yoon, R Vander Velde, A Marusyk, JG Scott
Bulletin of mathematical biology 80, 1776-1809, 2018
392018
Roadmap on plasticity and epigenetics in cancer
J Foo, D Basanta, RC Rockne, C Strelez, C Shah, K Ghaffarian, ...
Physical biology 19 (3), 031501, 2022
122022
Antifragile therapy
J West, B Desai, M Strobl, L Pierik, RV Velde, C Armagost, R Miles, ...
BioRxiv, 2020.10. 08.331678, 2020
82020
The neutral, hydrophobic isoleucine at position I521 in the extracellular S4 domain of hERG contributes to channel gating equilibrium
Y Dou, SJ Goodchild, RV Velde, Y Wu, D Fedida
American Journal of Physiology-Cell Physiology 305 (4), C468-C478, 2013
82013
Understanding the evolutionary games in NSCLC microenvironment
R Bhattacharya, RV Velde, V Marusyk, B Desai, A Kaznatcheev, ...
bioRxiv, 2020.11. 30.404350, 2020
72020
Integrating mutational and nonmutational mechanisms of acquired therapy resistance within the Darwinian paradigm
R Vander Velde, S Shaffer, A Marusyk
Trends in cancer 8 (6), 456-466, 2022
52022
The impact of tumor stromal architecture on therapy response and clinical progression
PM Altrock, N Yoon, JA Bull, H Wu, J Ruiz-Ramírez, D Miroshnychenko, ...
bioRxiv, 451047, 2018
52018
Clonal differences underlie variable responses to sequential and prolonged treatment
DL Schaff, AJ Fasse, PE White, RJ Vander Velde, SM Shaffer
Cell Systems, 2024
12024
Abstract A016: Positive ecological interaction between therapy-resistant and sensitive cells, mediated by stromal niche, slows the expansion of resistant subpopulations and …
B Desai, M Robertson-Tessi, RV Velde, T Miti, S Yarlagadda, R Shah, ...
Cancer Research 84 (3_Supplement_2), A016-A016, 2024
2024
Abstract A026: EGF/EGFR signaling in priming for resistance to BRAF/MEK inhibitors in melanoma
RJ Vander Velde, SM Shaffer
Cancer Research 84 (3_Supplement_2), A026-A026, 2024
2024
Abstract A013: Cell-extrinsic mechanisms of accelerated therapy resistance mediated by altered pharmacokinetics
P Kumar, RV Velde, V Turati, A Marusyk
Cancer Research 84 (3_Supplement_2), A013-A013, 2024
2024
Applying the principles of convexity and concavity to guide treatment scheduling of ALK inhibitors in non-small cell lung cancer
J West, B Desai, M Strobl, L Pierik, RV Velde, M Robertson-Tessi, ...
Cancer Research 83 (7_Supplement), 847-847, 2023
2023
Abstract B016: Selection and reprogramming contribute to the evolution of targeted therapy resistance
RV Velde, S Shaffer
Cancer Research 82 (10_Supplement), B016-B016, 2022
2022
Evolution of Targeted Therapy Resistance in EML4-ALK Positive Non-Small Cell Lung Cancer
R Vander Velde
University of South Florida, 2021
2021
Resistance to ALK targeting therapies as a gradual Darwinian adaptation to inhibitor specific selective pressures
R Vander Velde, N Yoon, V Marusyk, A Dhawan, O Balynska, B Desai, ...
bioRxiv, 504837, 2018
2018
Dark selection for JAK/STAT-inhibitor resistance in chronic myelomonocytic leukemia
A Kaznatcheev, DR Grimes, RV Velde, V Cannataro, E Baratchart, ...
bioRxiv, 211151, 2017
2017
Deciphering Evolution of Targeted Therapy Resistance in EML4-ALK NSCLC.
A Marusyk, R Vander Velde, V Marusyk, J Peacock, L Kenian, E Haura, ...
Journal of Thoracic Oncology 12 (8), S1547, 2017
2017
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