John Bertin
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NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis
E Elinav, T Strowig, AL Kau, J Henao-Mejia, CA Thaiss, CJ Booth, ...
Cell 145 (5), 745-757, 2011
Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan
SE Girardin, IG Boneca, LAM Carneiro, A Antignac, M Jéhanno, J Viala, ...
Science 300 (5625), 1584-1587, 2003
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island
J Viala, C Chaput, IG Boneca, A Cardona, SE Girardin, AP Moran, ...
Nature immunology 5 (11), 1166-1174, 2004
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages
L Franchi, A Amer, M Body-Malapel, TD Kanneganti, N Özören, ...
Nature immunology 7 (6), 576-582, 2006
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
TD Kanneganti, N Özören, M Body-Malapel, A Amer, JH Park, L Franchi, ...
Nature 440 (7081), 233-236, 2006
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1
FS Sutterwala, Y Ogura, M Szczepanik, M Lara-Tejero, GS Lichtenberger, ...
Immunity 24 (3), 317-327, 2006
The NLR gene family: a standard nomenclature
JPY Ting, RC Lovering, ES Alnemri, J Bertin, JM Boss, BK Davis, ...
Immunity 28 (3), 285-287, 2008
CARD4/Nod1 mediates NF-κB and JNK activation by invasive Shigella flexneri
SE Girardin, R Tournebize, M Mavris, AL Page, X Li, GR Stark, J Bertin, ...
EMBO reports 2 (8), 736-742, 2001
Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL
WJ Kaiser, H Sridharan, C Huang, P Mandal, JW Upton, PJ Gough, ...
Journal of Biological Chemistry 288 (43), 31268-31279, 2013
MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates
Y Dondelinger, W Declercq, S Montessuit, R Roelandt, A Goncalves, ...
Cell reports 7 (4), 971-981, 2014
Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas-and TNFR1-induced apoptosis
J Bertin, RC Armstrong, S Ottilie, DA Martin, Y Wang, S Banks, GH Wang, ...
Proceedings of the National Academy of Sciences 94 (4), 1172-1176, 1997
Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death
P Orning, D Weng, K Starheim, D Ratner, Z Best, B Lee, A Brooks, S Xia, ...
Science 362 (6418), 1064-1069, 2018
RIP3 induces apoptosis independent of pronecrotic kinase activity
P Mandal, SB Berger, S Pillay, K Moriwaki, C Huang, H Guo, JD Lich, ...
Molecular cell 56 (4), 481-495, 2014
Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-κB
J Bertin, WJ Nir, CM Fischer, OV Tayber, PR Errada, JR Grant, JJ Keilty, ...
Journal of Biological Chemistry 274 (19), 12955-12958, 1999
PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-κB and caspase-1-dependent cytokine processing
L Wang, GA Manji, JM Grenier, A Al-Garawi, S Merriam, JM Lora, ...
Journal of Biological Chemistry 277 (33), 29874-29880, 2002
A functional role for Nlrp6 in intestinal inflammation and tumorigenesis
GY Chen, M Liu, F Wang, J Bertin, G Núńez
The Journal of immunology 186 (12), 7187-7194, 2011
CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-κB
J Bertin, L Wang, Y Guo, MD Jacobson, JL Poyet, SM Srinivasula, ...
Journal of Biological Chemistry 276 (15), 11877-11882, 2001
Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis
M Lara-Tejero, FS Sutterwala, Y Ogura, EP Grant, J Bertin, AJ Coyle, ...
The Journal of experimental medicine 203 (6), 1407-1412, 2006
A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system
IG Boneca, O Dussurget, D Cabanes, MA Nahori, S Sousa, M Lecuit, ...
Proceedings of the National Academy of Sciences 104 (3), 997-1002, 2007
NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens
PK Anand, RK Malireddi, JR Lukens, P Vogel, J Bertin, M Lamkanfi, ...
Nature 488 (7411), 389-393, 2012
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