| Targeting of protein ubiquitination by BTB–Cullin 3–Roc1 ubiquitin ligases M Furukawa, YJ He, C Borchers, Y Xiong Nature cell biology 5 (11), 1001-1007, 2003 | 533 | 2003 |
| DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4–ROC1 ubiquitin ligases YJ He, CM McCall, J Hu, Y Zeng, Y Xiong Genes & development 20 (21), 2949-2954, 2006 | 380 | 2006 |
| Characterization of Arabidopsis and Rice DWD Proteins and Their Roles as Substrate Receptors for CUL4-RING E3 Ubiquitin Ligases JH Lee, W Terzaghi, G Gusmaroli, JBF Charron, HJ Yoon, H Chen, YJ He, ... The Plant Cell 20 (1), 152-167, 2008 | 281 | 2008 |
| DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells YJ He, K Meghani, MC Caron, C Yang, DA Ronato, J Bian, A Sharma, ... Nature 563 (7732), 522-526, 2018 | 192 | 2018 |
| WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1–CUL4–ROC1 ligase J Hu, S Zacharek, YJ He, H Lee, S Shumway, RJ Duronio, Y Xiong Genes & development 22 (7), 866-871, 2008 | 169 | 2008 |
| Platinum and PARP inhibitor resistance due to overexpression of microRNA-622 in BRCA1-mutant ovarian cancer YE Choi, K Meghani, ME Brault, L Leclerc, YJ He, TA Day, KM Elias, ... Cell reports 14 (3), 429-439, 2016 | 142 | 2016 |
| Cytoplasmic localized ubiquitin ligase cullin 7 binds to p53 and promotes cell growth by antagonizing p53 function P Andrews, YJ He, Y Xiong Oncogene 25 (33), 4534-4548, 2006 | 136 | 2006 |
| Aurora-A kinase is essential for bipolar spindle formation and early development DO Cowley, JA Rivera-Pérez, M Schliekelman, YJ He, TG Oliver, L Lu, ... Molecular and cellular biology 29 (4), 1059-1071, 2009 | 135 | 2009 |
| TIRR regulates 53BP1 by masking its histone methyl-lysine binding function P Drané, ME Brault, G Cui, K Meghani, S Chaubey, A Detappe, ... Nature 543 (7644), 211-216, 2017 | 125 | 2017 |
| Ribosomal protein–Mdm2–p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation Y Liu, Y He, A Jin, AP Tikunov, L Zhou, LA Tollini, P Leslie, TH Kim, LO Li, ... Proceedings of the National Academy of Sciences 111 (23), E2414-E2422, 2014 | 125 | 2014 |
| CHCHD2 inhibits apoptosis by interacting with Bcl-x L to regulate Bax activation Y Liu, HV Clegg, PL Leslie, J Di, LA Tollini, Y He, TH Kim, A Jin, ... Cell Death & Differentiation 22 (6), 1035-1046, 2015 | 106 | 2015 |
| p53 coordinates DNA repair with nucleotide synthesis by suppressing PFKFB3 expression and promoting the pentose phosphate pathway DA Franklin, Y He, PL Leslie, AP Tikunov, N Fenger, JM Macdonald, ... Scientific reports 6 (1), 38067, 2016 | 84 | 2016 |
| Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic … CM McCall, PL Miliani de Marval, PD Chastain, SC Jackson, YJ He, ... Molecular and cellular biology 28 (18), 5621-5633, 2008 | 80 | 2008 |
| SCFFBXO22 targets HDM2 for degradation and modulates breast cancer cell invasion and metastasis J Bai, K Wu, MH Cao, Y Yang, Y Pan, H Liu, Y He, Y Itahana, L Huang, ... Proceedings of the National Academy of Sciences 116 (24), 11754-11763, 2019 | 39 | 2019 |
| Identification of LIMK2 as a therapeutic target in castration resistant prostate cancer K Nikhil, L Chang, K Viccaro, M Jacobsen, C McGuire, SR Satapathy, ... Cancer letters 448, 182-196, 2019 | 25 | 2019 |
| The anaphase-promoting complex/cyclosome is an E3 ubiquitin ligase for Mdm2 Y He, L Tollini, TH Kim, Y Itahana, Y Zhang Cell Cycle 13 (13), 2101-2109, 2014 | 15 | 2014 |
| ASTE1 cutting to block DNA end resection YJ He, D Chowdhury Nature Cell Biology 23 (8), 818-819, 2021 | 5 | 2021 |
| CCAR2 functions downstream of the Shieldin complex to promote double-strand break end-joining DR Iyer, N Harada, C Clairmont, L Jiang, D Martignetti, H Nguyen, YJ He, ... Proceedings of the National Academy of Sciences 119 (49), e2214935119, 2022 | 4 | 2022 |
| Dynamics of the DYNLL1–MRE11 complex regulate DNA end resection and recruitment of Shieldin to DSBs ML Swift, R Zhou, A Syed, LA Moreau, B Tomasik, JA Tainer, ... Nature Structural & Molecular Biology 30 (10), 1456-1467, 2023 | 1 | 2023 |
| Abstract GMM-027: DYNLL1 INHIBITS DNA END RESECTION IN BRCA1-DEFICIENT CELLS AND REGULATES PARP INHIBITOR SENSITIVITY YJ He, K Meghani, MC Caron, C Yang, DA Ronato, J Bian, A Sharma, ... Clinical Cancer Research 25 (22_Supplement), GMM-027-GMM-027, 2019 | 1 | 2019 |
Yue XiongCullgen, Inc.Verified email at cullgen.com
Yue XiongCullgen, Inc.Verified email at cullgen.com