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Iain Chalmers
Iain Chalmers
Verified email at aber.ac.uk
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Year
Whole genome analysis of a schistosomiasis-transmitting freshwater snail
CM Adema, LDW Hillier, CS Jones, ES Loker, M Knight, P Minx, ...
Nature communications 8 (1), 15451, 2017
2532017
Anti-schistosomal intervention targets identified by lifecycle transcriptomic analyses
JM Fitzpatrick, E Peak, S Perally, IW Chalmers, J Barrett, TP Yoshino, ...
PLoS neglected tropical diseases 3 (11), e543, 2009
1492009
Developmentally regulated expression, alternative splicing and distinct sub-groupings in members of the Schistosoma mansoni venom allergen-like (SmVAL) gene …
IW Chalmers, AJ McArdle, RMR Coulson, MA Wagner, R Schmid, H Hirai, ...
BMC genomics 9, 1-20, 2008
1452008
Cytosine methylation regulates oviposition in the pathogenic blood fluke Schistosoma mansoni
KK Geyer, CM Rodríguez López, IW Chalmers, SE Munshi, M Truscott, ...
Nature communications 2 (1), 424, 2011
1192011
Development and Validation of a Quantitative, High-Throughput, Fluorescent-Based Bioassay to Detect Schistosoma Viability
E Peak, IW Chalmers, KF Hoffmann
PLoS neglected tropical diseases 4 (7), e759, 2010
1142010
Molecular characterization of omega-1: A hepatotoxic ribonuclease from Schistosoma mansonieggs
CM Fitzsimmons, G Schramm, FM Jones, IW Chalmers, KF Hoffmann, ...
Molecular & Biochemical Parasitology 144 (1), 123-127, 2005
1042005
The Schistosoma mansoni Tegumental-Allergen-Like (TAL) Protein Family: Influence of Developmental Expression on Human IgE Responses
CM Fitzsimmons, FM Jones, A Stearn, IW Chalmers, KF Hoffmann, ...
PLoS neglected tropical diseases 6 (4), e1593, 2012
782012
The scandalous failure of scientists to cumulate scientifically
I Chalmers
Abstract to paper presented at: Ninth World Congress on Health Information …, 2005
602005
Platyhelminth Venom Allergen-Like (VAL) proteins: revealing structural diversity, class-specific features and biological associations across the phylum
IW Chalmers, KF Hoffmann
Parasitology 139 (10), 1231-1245, 2012
552012
The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions …
KK Geyer, UH Niazi, D Duval, C Cosseau, C Tomlinson, IW Chalmers, ...
PLoS neglected tropical diseases 11 (5), e0005246, 2017
542017
Excreted/secreted Schistosoma mansoni venom allergen-like 9 (SmVAL9) modulates host extracellular matrix remodelling gene expression
TP Yoshino, M Brown, XJ Wu, CJ Jackson, R Ocadiz-Ruiz, IW Chalmers, ...
International journal for parasitology 44 (8), 551-563, 2014
492014
Cytosine methylation is a conserved epigenetic feature found throughout the phylum Platyhelminthes
KK Geyer, IW Chalmers, N MacKintosh, JE Hirst, R Geoghegan, M Badets, ...
BMC genomics 14, 1-13, 2013
442013
Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni
G Padalino, S Ferla, A Brancale, IW Chalmers, KF Hoffmann
International Journal for Parasitology: Drugs and Drug Resistance 8 (3), 559-570, 2018
412018
The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets
KCL Whatley, G Padalino, H Whiteland, KK Geyer, BJ Hulme, ...
PLoS Neglected Tropical Diseases 13 (11), e0007693, 2019
302019
Drug-Induced Exposure of Schistosoma mansoni Antigens SmCD59a and SmKK7
N Reimers, A Homann, B Höschler, K Langhans, RA Wilson, C Pierrot, ...
PLOS Neglected Tropical Diseases 9 (3), e0003593, 2015
302015
Switching from originator to biosimilar infliximab in paediatric inflammatory bowel disease is feasible and uneventful
L Gervais, LL McLean, ML Wilson, C Cameron, L Curtis, V Garrick, ...
Journal of pediatric gastroenterology and nutrition 67 (6), 745-748, 2018
292018
Schistosoma mansoni schistosomula antigens induce Th1/Pro‐inflammatory cytokine responses
M Egesa, L Lubyayi, EM Tukahebwa, BS Bagaya, IW Chalmers, S Wilson, ...
Parasite immunology 40 (12), e12592, 2018
282018
Known allergen structures predict Schistosoma mansoni IgE-binding antigens in human infection
EJ Farnell, N Tyagi, S Ryan, IW Chalmers, A Pinot de Moira, FM Jones, ...
Frontiers in immunology 6, 115922, 2015
252015
Comparison of porcine airway and intestinal epithelial cell lines for the susceptibility and expression of pattern recognition receptors upon influenza virus infection
M Thomas, M Pierson, T Uprety, L Zhu, Z Ran, CC Sreenivasan, D Wang, ...
Viruses 10 (6), 312, 2018
192018
Schistosoma mansoni arginase shares functional similarities with human orthologs but depends upon disulphide bridges for enzymatic activity
JM Fitzpatrick, JM Fuentes, IW Chalmers, TA Wynn, M Modolell, ...
International journal for parasitology 39 (3), 267-279, 2009
192009
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