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Shruthi Sriramkumar
Shruthi Sriramkumar
The University of Texas MD Anderson Cancer Center
Verified email at mdanderson.org
Title
Cited by
Cited by
Year
The role of inflammation and inflammatory mediators in the development, progression, metastasis, and chemoresistance of epithelial ovarian cancer
SS Savant, S Sriramkumar, HM O’Hagan
Cancers 10 (8), 251, 2018
1472018
Mismatch repair proteins initiate epigenetic alterations during inflammation-driven tumorigenesis
AR Maiuri, M Peng, R Podicheti, S Sriramkumar, CM Kamplain, DB Rusch, ...
Cancer research 77 (13), 3467-3478, 2017
522017
Bacterial-Driven Inflammation and Mutant BRAF Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy
CE DeStefano Shields, JR White, L Chung, A Wenzel, JL Hicks, AJ Tam, ...
Cancer discovery 11 (7), 1792-1807, 2021
472021
LSD1 and Aberrant DNA Methylation Mediate Persistence of Enteroendocrine Progenitors That Support BRAF-Mutant Colorectal Cancer
SA Miller, RA Policastro, S Sriramkumar, T Lai, TD Huntington, ...
Cancer research 81 (14), 3791-3805, 2021
432021
Platinum-induced mitochondrial OXPHOS contributes to cancer stem cell enrichment in ovarian cancer
S Sriramkumar, R Sood, TD Huntington, AH Ghobashi, TT Vuong, ...
Journal of Translational Medicine 20 (1), 246, 2022
332022
Lysine-Specific Demethylase 1 Mediates AKT Activity and Promotes Epithelial-to-Mesenchymal Transition in PIK3CA-Mutant Colorectal Cancer
SA Miller, RA Policastro, SS Savant, S Sriramkumar, N Ding, X Lu, ...
Molecular Cancer Research 18 (2), 264-277, 2020
322020
A novel ALDH1A1 inhibitor blocks platinum-induced senescence and stemness in ovarian cancer
V Muralikrishnan, F Fang, TC Given, R Podicheti, M Chtcherbinine, ...
Cancers 14 (14), 3437, 2022
142022
Platinum-induced ubiquitination of phosphorylated H2AX by RING1A is mediated by replication protein A in ovarian cancer
S Sriramkumar, TD Matthews, AH Ghobashi, SA Miller, ...
Molecular Cancer Research 18 (11), 1699-1710, 2020
132020
Single-cell analysis of a high-grade serous ovarian cancer cell line reveals transcriptomic changes and cell subpopulations sensitive to epigenetic combination treatment
S Sriramkumar, TX Metcalfe, T Lai, X Zong, F Fang, HM O’Hagan, ...
Plos one 17 (8), e0271584, 2022
62022
Bacterial-driven inflammation and mutant BRAF expression Combine to promote Murine colon tumorigenesis that is Sensitive to immune checkpoint therapy. Cancer Discovery. 2021 …
CE DeStefano Shields, JR White, L Chung, A Wenzel, JL Hicks, AJ Tam, ...
Annu Rev Med 72, 243-261, 2021
62021
Novel epigenetic-metabolic inhibitor combination treatment blocks platinum-induced ovarian cancer stem cell enrichment
R Sood, S Xiao, S Sriramkumar, C Hassel, KP Nephew, HM O’Hagan
Biorxiv, 2021
32021
LSD1 promotes secretory cell specification to drive BRAF mutant colorectal cancer
SA Miller, RA Policastro, S Sriramkumar, T Lai, TD Huntington, ...
bioRxiv, 2020.09. 25.313536, 2020
22020
Abstract B029: Targeting non-canonical function of TXNRD1 to overcome platinum resistance by eradicating ovarian cancer stem-like cells
M Towers, X Hao, S Sriramkumar, W Zhou, R Zhang
Cancer Research 84 (5_Supplement_2), B029-B029, 2024
2024
Targeting non-canonical function of TXNRD1 to overcome platinum resistance by eradicating ovarian cancer stem-like cells
M Towers, X Hao, S Sriramkumar, W Zhou, R Zhang
CANCER RESEARCH 84 (5), 2024
2024
Platinum-inducedBRCA1 promoter DNA hypermethylation and altered metabolic profile promotes chemoresistance in ovarian cancer
R Sood, S Xiao, S Sriramkumar, C Hassel, K Nephew, H O'Hagan
Cancer Research 81 (13_Supplement), 2110-2110, 2021
2021
Combined epigenetic and metabolic inhibition blocks platinum-induced ovarian cancer stem cell enrichment
R Sood, S Sriramkumar, V Muralikrishnan, S Xiao, W Wang, C Hassel, ...
bioRxiv, 2021.03. 18.435878, 2021
2021
The Role of Platinum-Mediated Chromatin and Metabolic Alterations in Ovarian Cancer Chemoresistance
S Sriramkumar
Indiana University, 2021
2021
Abstract GMM-055: BMI1 AND RING1A ARE INVOLVED IN H2A UBIQUITINATION AT SITES OF PLATINUM-INDUCED DAMAGE
S Sriramkumar, HM O'Hagan
Clinical Cancer Research 25 (22_Supplement), GMM-055-GMM-055, 2019
2019
RING1A Ubiquitinates Histone H2A at Sites of Platinum-Induced Damage.
HM O'Hagan, S Sriramkumar
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 60, 52-53, 2019
2019
BMI1 and RING1A are involved in H2A ubiquitination at sites of platinum-induced damage
S Sriramkumar, HM O'Hagan
Cancer Research 79 (13_Supplement), 2576-2576, 2019
2019
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