Mitochondrial precursor protein. Effects of 70-kilodalton heat shock protein on polypeptide folding, aggregation, and import competence. WP Sheffield, GC Shore, SK Randall Journal of Biological Chemistry 265 (19), 11069-11076, 1990 | 201 | 1990 |
Potent antithrombin activity and delayed clearance from the circulation characterize recombinant hirudin genetically fused to albumin S Syed, PD Schuyler, M Kulczycky, WP Sheffield Blood, The Journal of the American Society of Hematology 89 (9), 3243-3252, 1997 | 153 | 1997 |
Prothrombin complex concentrates reduce blood loss in murine coagulopathy induced by warfarin, but not in that induced by dabigatran etexilate MD Lambourne, LJ Eltringham‐Smith, S Gataiance, DM Arnold, ... Journal of Thrombosis and Haemostasis 10 (9), 1830-1840, 2012 | 122 | 2012 |
Impaired Procoagulant-anticoagulant Balance during Hormone Replacement Therapy? WM van Baal, JJ Emeis, MJ van der Mooren, H Kessel, P Kenemans, ... Thrombosis and haemostasis 83 (01), 29-34, 2000 | 121 | 2000 |
Molecular basis of inherited human antithrombin deficiency MA Blajchman, RC Austin, F Fernandez-Rachubinski, WP Sheffield | 112 | 1992 |
Quality assessment of established and emerging blood components for transfusion JP Acker, DC Marks, WP Sheffield Journal of blood transfusion 2016 (1), 4860284, 2016 | 91 | 2016 |
Phosphatidylserine externalization and procoagulant activation of erythrocytes induced by Pseudomonas aeruginosa virulence factor pyocyanin SM Qadri, DA Donkor, V Bhakta, LJ Eltringham‐Smith, DJ Dwivedi, ... Journal of cellular and molecular medicine 20 (4), 710-720, 2016 | 86 | 2016 |
Cytokeratin 18 is expressed on the hepatocyte plasma membrane surface and interacts with thrombin-antithrombin complexes MJ Wells, MWC Hatton, B Hewlett, TJ Podor, WP Sheffield, MA Blajchman Journal of Biological Chemistry 272 (45), 28574-28581, 1997 | 70 | 1997 |
Modification of clearance of therapeutic and potentially therapeutic proteins WP Sheffield Current Drug Targets-Cardiovascular & Hematological Disorders 1 (1), 1-22, 2001 | 62 | 2001 |
Effects of genetic fusion of factor IX to albumin on in vivo clearance in mice and rabbits WP Sheffield, A Mamdani, G Hortelano, S Gataiance, L Eltringham‐Smith, ... British journal of haematology 126 (4), 565-573, 2004 | 60 | 2004 |
Accelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2 E Lang, R Bissinger, A Fajol, MS Salker, Y Singh, C Zelenak, ... Scientific reports 5 (1), 17316, 2015 | 55 | 2015 |
Prolonged in vivo anticoagulant activity of a hirudin–albumin fusion protein secreted from Pichia pastoris WP Sheffield, IJ Smith, S Syed, V Bhakta Blood coagulation & fibrinolysis 12 (6), 433-443, 2001 | 51 | 2001 |
A barbourin-albumin fusion protein that is slowly cleared in vivo retains the ability to inhibit platelet aggregation in vitro JA Marques, JK George, IJ Smith, V Bhakta, WP Sheffield Thrombosis and haemostasis 86 (09), 902-908, 2001 | 51 | 2001 |
Selection and characterization of a DNA aptamer inhibiting coagulation factor XIa DA Donkor, V Bhakta, LJ Eltringham-Smith, AR Stafford, JI Weitz, ... Scientific Reports 7 (1), 2102, 2017 | 49 | 2017 |
Pathogen inactivation by riboflavin and ultraviolet light illumination accelerates the red blood cell storage lesion and promotes eryptosis SM Qadri, D Chen, P Schubert, DL Perruzza, V Bhakta, DV Devine, ... Transfusion 57 (3), 661-673, 2017 | 48 | 2017 |
Modulation of clearance of recombinant serum albumin by either glycosylation or truncation WP Sheffield, JA Marques, V Bhakta, IJ Smith Thrombosis research 99 (6), 613-621, 2000 | 47 | 2000 |
Whole blood treated with riboflavin and ultraviolet light: quality assessment of all blood components produced by the buffy coat method P Schubert, B Culibrk, S Karwal, K Serrano, E Levin, D Bu, V Bhakta, ... Transfusion 55 (4), 815-823, 2015 | 46 | 2015 |
CD44 antibody inhibition of macrophage phagocytosis targets Fcγ receptor–and complement receptor 3–dependent mechanisms A Amash, L Wang, Y Wang, V Bhakta, GD Fairn, M Hou, J Peng, ... The Journal of Immunology 196 (8), 3331-3340, 2016 | 42 | 2016 |
An important role for the activation peptide domain in controlling factor IX levels in the blood of haemophilia B mice ME Begbie, A Mamdani, S Gataiance, LJ Eltringham-Smith, V Bhakta, ... Thrombosis and haemostasis 94 (12), 1138-1147, 2005 | 39 | 2005 |
The clearance of thrombin-antithrombin and related serpin-enzyme complexes from the circulation: role of various hepatocyte receptors MJ Wells, WP Sheffield, MA Blajchman Thrombosis and haemostasis 81 (03), 325-337, 1999 | 39 | 1999 |