Michele Moschetta, MD PhD
Michele Moschetta, MD PhD
Executive Director, Early Clinical Development Oncology, AstraZeneca
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Targeting the bone marrow microenvironment in multiple myeloma
Y Kawano, M Moschetta, S Manier, S Glavey, GT Görgün, AM Roccaro, ...
Immunological reviews 263 (1), 160-172, 2015
APRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment
YT Tai, C Acharya, G An, M Moschetta, MY Zhong, X Feng, M Cea, ...
Blood, The Journal of the American Society of Hematology 127 (25), 3225-3236, 2016
BRCA somatic mutations and epigenetic BRCA modifications in serous ovarian cancer
M Moschetta, A George, SB Kaye, S Banerjee
Annals of Oncology 27 (8), 1449-1455, 2016
Engineered nanomedicine for myeloma and bone microenvironment targeting
A Swami, MR Reagan, P Basto, Y Mishima, N Kamaly, S Glavey, S Zhang, ...
Proceedings of the National Academy of Sciences 111 (28), 10287-10292, 2014
Metabolic signature identifies novel targets for drug resistance in multiple myeloma
P Maiso, D Huynh, M Moschetta, A Sacco, Y Aljawai, Y Mishima, ...
Cancer research 75 (10), 2071-2082, 2015
C1013G/CXCR4 acts as a driver mutation of tumor progression and modulator of drug resistance in lymphoplasmacytic lymphoma
AM Roccaro, A Sacco, C Jimenez, P Maiso, M Moschetta, Y Mishima, ...
Blood, The Journal of the American Society of Hematology 123 (26), 4120-4131, 2014
SDF-1 inhibition targets the bone marrow niche for cancer therapy
AM Roccaro, A Sacco, WG Purschke, M Moschetta, K Buchner, C Maasch, ...
Cell reports 9 (1), 118-128, 2014
Therapeutic targeting of the mTOR‐signalling pathway in cancer: benefits and limitations
M Moschetta, A Reale, C Marasco, A Vacca, MR Carratù
British journal of pharmacology 171 (16), 3801-3813, 2014
CXCR4 regulates extra-medullary myeloma through epithelial-mesenchymal-transition-like transcriptional activation
AM Roccaro, Y Mishima, A Sacco, M Moschetta, YT Tai, J Shi, Y Zhang, ...
Cell reports 12 (4), 622-635, 2015
The developing story of predictive biomarkers in colorectal cancer
S Boussios, MA Ozturk, M Moschetta, A Karathanasi, ...
Journal of personalized medicine 9 (1), 12, 2019
The cancer glycome: carbohydrates as mediators of metastasis
SV Glavey, D Huynh, MR Reagan, S Manier, M Moschetta, Y Kawano, ...
Blood reviews 29 (4), 269-279, 2015
Role of endothelial progenitor cells in cancer progression
M Moschetta, Y Mishima, I Sahin, S Manier, S Glavey, A Vacca, ...
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1846 (1), 26-39, 2014
The sialyltransferase ST3GAL6 influences homing and survival in multiple myeloma
SV Glavey, S Manier, A Natoni, A Sacco, M Moschetta, MR Reagan, ...
Blood, The Journal of the American Society of Hematology 124 (11), 1765-1776, 2014
Combined strategies with poly (ADP-Ribose) polymerase (PARP) inhibitors for the treatment of ovarian cancer: a literature review
S Boussios, P Karihtala, M Moschetta, A Karathanasi, A Sadauskaite, ...
Diagnostics 9 (3), 87, 2019
Bone marrow fibroblasts parallel multiple myeloma progression in patients and mice: in vitro and in vivo studies
MA Frassanito, L Rao, M Moschetta, R Ria, L Di Marzo, A De Luisi, ...
Leukemia 28 (4), 904-916, 2014
Paclitaxel enhances therapeutic efficacy of the F8-IL2 immunocytokine to EDA-fibronectin–positive metastatic human melanoma xenografts
M Moschetta, F Pretto, A Berndt, K Galler, P Richter, A Bassi, P Oliva, ...
Cancer research 72 (7), 1814-1824, 2012
Poly (ADP-Ribose) polymerase inhibitors: talazoparib in ovarian cancer and beyond
S Boussios, C Abson, M Moschetta, E Rassy, A Karathanasi, T Bhat, ...
Drugs in R&D 20, 55-73, 2020
Blocking IFNAR1 inhibits multiple myeloma–driven Treg expansion and immunosuppression
Y Kawano, O Zavidij, J Park, M Moschetta, K Kokubun, TH Mouhieddine, ...
The Journal of clinical investigation 128 (6), 2487-2499, 2018
Antibody dependent cellular phagocytosis by macrophages is a novel mechanism of action of elotuzumab.
K AT, G SV, B NA, J A, G JL, M S, M M, M Y, R A, D A, L CJ, S A, H D, T YT, ...
Mol Cancer Ther., 2018
Proteomic characterization of human multiple myeloma bone marrow extracellular matrix
SV Glavey, A Naba, S Manier, K Clauser, S Tahri, J Park, MR Reagan, ...
Leukemia 31 (11), 2426-2434, 2017
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