The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn–/–mice and results in a mouse with spinal muscular atrophy UR Monani, M Sendtner, DD Coovert, DW Parsons, C Andreassi, TT Le, ... Human molecular genetics 9 (3), 333-339, 2000 | 881 | 2000 |
Smn, the spinal muscular atrophy–determining gene product, modulates axon growth and localization of β-actin mRNA in growth cones of motoneurons W Rossoll, S Jablonka, C Andreassi, AK Kröning, K Karle, UR Monani, ... The Journal of cell biology 163 (4), 801-812, 2003 | 791 | 2003 |
Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis CH Wu, C Fallini, N Ticozzi, PJ Keagle, PC Sapp, K Piotrowska, P Lowe, ... Nature 488 (7412), 499-503, 2012 | 727 | 2012 |
Plastin 3 is a protective modifier of autosomal recessive spinal muscular atrophy GE Oprea, S Kröber, ML McWhorter, W Rossoll, S Müller, M Krawczak, ... Science 320 (5875), 524-527, 2008 | 609 | 2008 |
TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD CC Chou, YI Zhang, ME Umoh, SW Vaughan, I Lorenzini, F Liu, ... Nature neuroscience 21 (2), 228-239, 2018 | 494 | 2018 |
Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons? W Rossoll, AK Kröning, UM Ohndorf, C Steegborn, S Jablonka, ... Human molecular genetics 11 (1), 93-105, 2002 | 397 | 2002 |
The survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly (A) mRNA in primary motor neuron axons C Fallini, H Zhang, Y Su, V Silani, RH Singer, W Rossoll, GJ Bassell Journal of Neuroscience 31 (10), 3914-3925, 2011 | 273 | 2011 |
The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth C Fallini, GJ Bassell, W Rossoll Human molecular genetics 21 (16), 3703-3718, 2012 | 271 | 2012 |
Multiprotein complexes of the survival of motor neuron protein SMN with Gemins traffic to neuronal processes and growth cones of motor neurons H Zhang, L Xing, W Rossoll, H Wichterle, RH Singer, GJ Bassell Journal of Neuroscience 26 (33), 8622-8632, 2006 | 254 | 2006 |
Spinal muscular atrophy: the role of SMN in axonal mRNA regulation C Fallini, GJ Bassell, W Rossoll Brain research 1462, 81-92, 2012 | 244 | 2012 |
Reduced survival motor neuron (Smn) gene dose in mice leads to motor neuron degeneration: an animal model for spinal muscular atrophy type III S Jablonka, B Schrank, M Kralewski, W Rossoll, M Sendtner Human molecular genetics 9 (3), 341-346, 2000 | 228 | 2000 |
Deficiency of the survival of motor neuron protein impairs mRNA localization and local translation in the growth cone of motor neurons C Fallini, PG Donlin-Asp, JP Rouanet, GJ Bassell, W Rossoll Journal of Neuroscience 36 (13), 3811-3820, 2016 | 181 | 2016 |
Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells R Götz, S Wiese, S Takayama, GC Camarero, W Rossoll, U Schweizer, ... Nature neuroscience 8 (9), 1169-1178, 2005 | 154 | 2005 |
Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motoneuron disease H Bömmel, G Xie, W Rossoll, S Wiese, S Jablonka, T Boehm, ... The Journal of cell biology 159 (4), 563-569, 2002 | 148 | 2002 |
The heterogeneous nuclear ribonucleoprotein-R is necessary for axonal β-actin mRNA translocation in spinal motor neurons M Glinka, T Herrmann, N Funk, S Havlicek, W Rossoll, C Winkler, ... Human molecular genetics 19 (10), 1951-1966, 2010 | 136 | 2010 |
Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination EB Dammer, C Fallini, YM Gozal, DM Duong, W Rossoll, P Xu, JJ Lah, ... PloS one 7 (6), e38658, 2012 | 130 | 2012 |
Dysregulation of mRNA localization and translation in genetic disease ET Wang, JM Taliaferro, JA Lee, IP Sudhakaran, W Rossoll, C Gross, ... Journal of Neuroscience 36 (45), 11418-11426, 2016 | 116 | 2016 |
Characterization of Ighmbp2 in motor neurons and implications for the pathomechanism in a mouse model of human spinal muscular atrophy with respiratory distress type 1 (SMARD1) K Grohmann, W Rossoll, I Kobsar, B Holtmann, S Jablonka, C Wessig, ... Human molecular genetics 13 (18), 2031-2042, 2004 | 115 | 2004 |
Dynamics of survival of motor neuron (SMN) protein interaction with the mRNA‐binding protein IMP1 facilitates its trafficking into motor neuron axons C Fallini, JP Rouanet, PG Donlin‐Asp, P Guo, H Zhang, RH Singer, ... Developmental neurobiology 74 (3), 319-332, 2014 | 113 | 2014 |
The COPI vesicle complex binds and moves with survival motor neuron within axons CJ Peter, M Evans, V Thayanithy, N Taniguchi-Ishigaki, I Bach, A Kolpak, ... Human molecular genetics 20 (9), 1701-1711, 2011 | 99 | 2011 |