Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML CD DiNardo, IS Tiong, A Quaglieri, S MacRaild, S Loghavi, FC Brown, ... Blood, The Journal of the American Society of Hematology 135 (11), 791-803, 2020 | 469 | 2020 |
Targeting an RNA-binding protein network in acute myeloid leukemia E Wang, SX Lu, A Pastore, X Chen, J Imig, SCW Lee, K Hockemeyer, ... Cancer cell 35 (3), 369-384. e7, 2019 | 248 | 2019 |
Targeting mitochondrial structure sensitizes acute myeloid leukemia to venetoclax treatment X Chen, C Glytsou, H Zhou, S Narang, DE Reyna, A Lopez, ... Cancer discovery 9 (7), 890-909, 2019 | 207 | 2019 |
Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia A Kloetgen, P Thandapani, P Ntziachristos, Y Ghebrechristos, S Nomikou, ... Nature genetics 52 (4), 388-400, 2020 | 140 | 2020 |
SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2 Q Lu, J Liu, S Zhao, MFG Castro, M Laurent-Rolle, J Dong, X Ran, ... Immunity 54 (6), 1304-1319. e9, 2021 | 133 | 2021 |
Uhrf1 controls the self-renewal versus differentiation of hematopoietic stem cells by epigenetically regulating the cell-division modes J Zhao, X Chen, G Song, J Zhang, H Liu, X Liu Proceedings of the National Academy of Sciences 114 (2), E142-E151, 2017 | 57 | 2017 |
Surface antigen-guided CRISPR screens identify regulators of myeloid leukemia differentiation E Wang, H Zhou, B Nadorp, G Cayanan, X Chen, AH Yeaton, S Nomikou, ... Cell Stem Cell 28 (4), 718-731. e6, 2021 | 46 | 2021 |
Uhrf1 controls iNKT cell survival and differentiation through the Akt-mTOR axis Y Cui, X Chen, J Zhang, X Sun, H Liu, L Bai, C Xu, X Liu Cell Reports 15 (2), 256-263, 2016 | 36 | 2016 |
A membrane-associated MHC-I inhibitory axis for cancer immune evasion X Chen, Q Lu, H Zhou, J Liu, B Nadorp, A Lasry, Z Sun, B Lai, G Rona, ... Cell 186 (18), 3903-3920. e21, 2023 | 23 | 2023 |
Interferon regulatory factor 4 regulates thymocyte differentiation by repressing Runx3 expression Y Cao, H Li, Y Sun, X Chen, H Liu, X Gao, X Liu European journal of immunology 40 (11), 3198-3209, 2010 | 23 | 2010 |
Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion E Battistello, KA Hixon, DE Comstock, CK Collings, X Chen, JR Hernaez, ... Molecular cell 83 (8), 1216-1236. e12, 2023 | 15 | 2023 |
The mediator subunit Med23 contributes to controlling T-cell activation and prevents autoimmunity Y Sun, X Zhu, X Chen, H Liu, Y Xu, Y Chu, G Wang, X Liu Nature Communications 5 (1), 5225, 2014 | 13 | 2014 |
Lis1 is required for the expansion of hematopoietic stem cells in the fetal liver X Chen, J Zhang, J Zhao, H Liu, X Sun, M Zhao, X Liu Cell research 24 (8), 1013-1016, 2014 | 11 | 2014 |
Lis1 regulates germinal center B cell antigen acquisition and affinity maturation J Chen, Z Cai, L Zhang, Y Yin, X Chen, C Chen, Y Zhang, S Zhai, X Long, ... The Journal of Immunology 198 (11), 4304-4311, 2017 | 8 | 2017 |
Dynamic 3D chromosomal landscapes in acute leukemia A Kloetgen, P Thandapani, P Ntziachristos, Y Ghebrechristos, S Nomikou, ... bioRxiv, 724427, 2019 | 7 | 2019 |
Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia C Glytsou, X Chen, E Zacharioudakis, W Al-Santli, H Zhou, B Nadorp, ... Cancer discovery 13 (7), 1656-1677, 2023 | 6 | 2023 |
Med23 serves as a gatekeeper of the myeloid potential of hematopoietic stem cells X Chen, J Zhao, C Gu, Y Cui, Y Dai, G Song, H Liu, H Shen, Y Liu, ... Nature Communications 9 (1), 3746, 2018 | 6 | 2018 |
Targeting MHC-I inhibitory pathways for cancer immunotherapy J Wang, Q Lu, X Chen, I Aifantis Trends in Immunology, 2024 | | 2024 |
The effect of chromatin states on cancer: big data lead the way X Chen, I Aifantis The Lancet Haematology 5 (6), e237-e238, 2018 | | 2018 |