|Phosphorylation of membrane type 1-matrix metalloproteinase (MT1-MMP) and its vesicle-associated membrane protein 7 (VAMP7)-dependent trafficking facilitate cell invasion and …|
KC Williams, MG Coppolino
Journal of Biological Chemistry 286 (50), 43405-43416, 2011
|VAMP3, syntaxin-13 and SNAP23 are involved in secretion of matrix metalloproteinases, degradation of the extracellular matrix and cell invasion|
MJ Kean, KC Williams, M Skalski, D Myers, A Burtnik, D Foster, ...
Journal of cell science 122 (22), 4089-4098, 2009
|SNAP23, Syntaxin4, and vesicle-associated membrane protein 7 (VAMP7) mediate trafficking of membrane type 1–matrix metalloproteinase (MT1-MMP) during invadopodium formation and …|
KC Williams, RE McNeilly, MG Coppolino
Molecular biology of the cell 25 (13), 2061-2070, 2014
|SNARE-dependent interaction of Src, EGFR and β1 integrin regulates invadopodia formation and tumor cell invasion|
KC Williams, MG Coppolino
Journal of cell science 127 (8), 1712-1725, 2014
|Quantification of cancer cell extravasation in vivo|
Y Kim, KC Williams, CT Gavin, E Jardine, AF Chambers, HS Leong
Nature protocols 11 (5), 937, 2016
|SNX9 promotes metastasis by enhancing cancer cell invasion via differential regulation of RhoGTPases|
N Bendris, KC Williams, CR Reis, ES Welf, PH Chen, B Lemmers, ...
Molecular biology of the cell 27 (9), 1409-1419, 2016
|Lamellipodium extension and membrane ruffling require different SNARE-mediated trafficking pathways|
M Skalski, Q Yi, MJ Kean, DW Myers, KC Williams, A Burtnik, ...
BMC cell biology 11 (1), 1-17, 2010
|Immunoaffinity based methods are superior to kits for purification of prostate derived extracellular vesicles from plasma samples|
SI Brett, F Lucien, C Guo, KC Williams, Y Kim, PN Durfee, CJ Brinker, ...
The Prostate 77 (13), 1335-1343, 2017
|SNARE-mediated membrane traffic is required for focal adhesion kinase signaling and Src-regulated focal adhesion turnover|
M Skalski, N Sharma, K Williams, A Kruspe, MG Coppolino
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (1), 148-158, 2011
|Less is more: low expression of MT1-MMP is optimal to promote migration and tumourigenesis of breast cancer cells|
MA Cepeda, JJH Pelling, CL Evered, KC Williams, Z Freedman, I Stan, ...
Molecular cancer 15 (1), 65, 2016
|Analytical considerations in nanoscale flow cytometry of extracellular vesicles to achieve data linearity|
J Gomes, F Lucien, TT Cooper, Y Kim, KC Williams, XY Liao, L Kaufman, ...
Thrombosis and haemostasis 118 (09), 1612-1624, 2018
|Invadopodia are chemosensing protrusions that guide cancer cell extravasation to promote brain tropism in metastasis|
KC Williams, MA Cepeda, S Javed, K Searle, KM Parkins, AV Makela, ...
Oncogene 38 (19), 3598-3615, 2019
|Nanoscale flow cytometry to distinguish subpopulations of prostate extracellular vesicles in patient plasma|
RS Padda, FK Deng, SI Brett, CN Biggs, PN Durfee, CJ Brinker, ...
The Prostate 79 (6), 592-603, 2019
|TBX3 promotes progression of pre‐invasive breast cancer cells by inducing EMT and directly up‐regulating SLUG|
M Krstic, B Kolendowski, MJ Cecchini, CO Postenka, HM Hassan, ...
The Journal of pathology 248 (2), 191-203, 2019
|Cancer dissemination from a physical sciences perspective|
KC Williams, E Wong, HS Leong, DN Jackson, AL Allan, AF Chambers
Convergent Science Physical Oncology 2 (2), 023001, 2016
|Triple-Negative Primary Breast Tumors Induce Supportive Premetastatic Changes in the Extracellular Matrix and Soluble Components of the Lung Microenvironment|
B Medeiros, D Goodale, C Postenka, LE Lowes, P Kiser, S Hearn, ...
Cancers 12 (1), 172, 2020
|Methods for diagnosing high-risk cancer using polysialic acid and one or more tissue-specific biomarkers|
K Williams, HS Leong
US Patent App. 16/611,596, 2020