Karla Williams
Karla Williams
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VAMP3, syntaxin-13 and SNAP23 are involved in secretion of matrix metalloproteinases, degradation of the extracellular matrix and cell invasion
MJ Kean, KC Williams, M Skalski, D Myers, A Burtnik, D Foster, ...
Journal of cell science 122 (22), 4089-4098, 2009
Phosphorylation of membrane type 1-matrix metalloproteinase (MT1-MMP) and its vesicle-associated membrane protein 7 (VAMP7)-dependent trafficking facilitate cell invasion and …
KC Williams, MG Coppolino
Journal of Biological Chemistry 286 (50), 43405-43416, 2011
SNAP23, Syntaxin4, and vesicle-associated membrane protein 7 (VAMP7) mediate trafficking of membrane type 1–matrix metalloproteinase (MT1-MMP) during invadopodium formation and …
KC Williams, RE McNeilly, MG Coppolino
Molecular biology of the cell 25 (13), 2061-2070, 2014
SNARE-dependent interaction of Src, EGFR and β1 integrin regulates invadopodia formation and tumor cell invasion
KC Williams, MG Coppolino
Journal of cell science 127 (8), 1712-1725, 2014
Immunoaffinity based methods are superior to kits for purification of prostate derived extracellular vesicles from plasma samples
SI Brett, F Lucien, C Guo, KC Williams, Y Kim, PN Durfee, CJ Brinker, ...
The Prostate 77 (13), 1335-1343, 2017
Quantification of cancer cell extravasation in vivo
Y Kim, KC Williams, CT Gavin, E Jardine, AF Chambers, HS Leong
Nature protocols 11 (5), 937-948, 2016
SNX9 promotes metastasis by enhancing cancer cell invasion via differential regulation of RhoGTPases
N Bendris, KC Williams, CR Reis, ES Welf, PH Chen, B Lemmers, ...
Molecular biology of the cell 27 (9), 1409-1419, 2016
Invadopodia are chemosensing protrusions that guide cancer cell extravasation to promote brain tropism in metastasis
KC Williams, MA Cepeda, S Javed, K Searle, KM Parkins, AV Makela, ...
Oncogene 38 (19), 3598-3615, 2019
Less is more: low expression of MT1-MMP is optimal to promote migration and tumourigenesis of breast cancer cells
MA Cepeda, JJH Pelling, CL Evered, KC Williams, Z Freedman, I Stan, ...
Molecular cancer 15, 1-27, 2016
Analytical considerations in nanoscale flow cytometry of extracellular vesicles to achieve data linearity
J Gomes, F Lucien, TT Cooper, Y Kim, KC Williams, XY Liao, L Kaufman, ...
Thrombosis and haemostasis 118 (09), 1612-1624, 2018
Nanoscale flow cytometry to distinguish subpopulations of prostate extracellular vesicles in patient plasma
RS Padda, FK Deng, SI Brett, CN Biggs, PN Durfee, CJ Brinker, ...
The Prostate 79 (6), 592-603, 2019
Lamellipodium extension and membrane ruffling require different SNARE-mediated trafficking pathways
M Skalski, Q Yi, MJ Kean, DW Myers, KC Williams, A Burtnik, ...
BMC cell biology 11, 1-17, 2010
TBX3 promotes progression of pre‐invasive breast cancer cells by inducing EMT and directly up‐regulating SLUG
M Krstic, B Kolendowski, MJ Cecchini, CO Postenka, HM Hassan, ...
The Journal of pathology 248 (2), 191-203, 2019
A versatile soluble siglec scaffold for sensitive and quantitative detection of glycan ligands
E Rodrigues, J Jung, H Park, C Loo, S Soukhtehzari, EN Kitova, ...
Nature communications 11 (1), 5091, 2020
SNARE-mediated membrane traffic is required for focal adhesion kinase signaling and Src-regulated focal adhesion turnover
M Skalski, N Sharma, K Williams, A Kruspe, MG Coppolino
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (1), 148-158, 2011
Triple-negative primary breast tumors induce supportive premetastatic changes in the extracellular matrix and soluble components of the lung microenvironment
B Medeiros, D Goodale, C Postenka, LE Lowes, P Kiser, S Hearn, ...
Cancers 12 (1), 172, 2020
Clinical significance of STEAP1 extracellular vesicles in prostate cancer
K Khanna, N Salmond, KS Lynn, HS Leong, KC Williams
Prostate cancer and prostatic diseases, 2021
Nanoscale flow cytometry for immunophenotyping and quantitating extracellular vesicles in blood plasma
N Salmond, K Khanna, GR Owen, KC Williams
Nanoscale 13, 2012-2025, 2021
Isolation and characterization of extracellular vesicles for clinical applications in cancer–time for standardization?
N Salmond, KC Williams
Nanoscale Advances 3, 1830-1852, 2021
Cancer dissemination from a physical sciences perspective
KC Williams, E Wong, HS Leong, DN Jackson, AL Allan, AF Chambers
Convergent Science Physical Oncology 2 (2), 023001, 2016
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