| Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution M Chan-Seng-Yue, JC Kim, GW Wilson, K Ng, EF Figueroa, GM O’Kane, ... Nature genetics 52 (2), 231-240, 2020 | 432 | 2020 |
| Prevention of depressive behaviour in the YAC128 mouse model of Huntington disease by mutation at residue 586 of huntingtin MA Pouladi, RK Graham, JM Karasinska, Y Xie, RD Santos, Ĺ Petersén, ... Brain 132 (4), 919-932, 2009 | 180 | 2009 |
| Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes M Valenza, V Leoni, JM Karasinska, L Petricca, J Fan, J Carroll, ... Journal of Neuroscience 30 (32), 10844-10850, 2010 | 169 | 2010 |
| Regulation of pH by carbonic anhydrase 9 mediates survival of pancreatic cancer cells with activated KRAS in response to hypoxia PC McDonald, SC Chafe, WS Brown, S Saberi, M Swayampakula, ... Gastroenterology 157 (3), 823-837, 2019 | 166 | 2019 |
| Cholesterol metabolism in Huntington disease JM Karasinska, MR Hayden Nature Reviews Neurology 7 (10), 561-572, 2011 | 163 | 2011 |
| Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function JM Karasinska, F Rinninger, D Lütjohann, P Ruddle, S Franciosi, JK Kruit, ... Journal of Neuroscience 29 (11), 3579-3589, 2009 | 157 | 2009 |
| NRG1 Gene Fusions Are Recurrent, Clinically Actionable Gene Rearrangements in KRAS Wild-Type Pancreatic Ductal Adenocarcinoma MR Jones, LM Williamson, JT Topham, MKC Lee, A Goytain, J Ho, ... Clinical Cancer Research 25 (15), 4674-4681, 2019 | 143 | 2019 |
| Altered gene expression along the glycolysis–cholesterol synthesis axis is associated with outcome in pancreatic cancer JM Karasinska, JT Topham, SE Kalloger, GH Jang, RE Denroche, ... Clinical Cancer Research 26 (1), 135-146, 2020 | 134 | 2020 |
| Physicochemical differences in the AH receptors of the most TCDD-susceptible and the most TCDD-resistant rat strains R Pohjanvirta, M Viluksela, JT Tuomisto, M Unkila, J Karasinska, ... Toxicology and applied pharmacology 155 (1), 82-95, 1999 | 130 | 1999 |
| Pan-cancer analysis of advanced patient tumors reveals interactions between therapy and genomic landscapes E Pleasance, E Titmuss, L Williamson, H Kwan, L Culibrk, EY Zhao, ... Nature Cancer 1 (4), 452-468, 2020 | 121 | 2020 |
| Spontaneous atherosclerosis in aged lipoprotein lipase–deficient mice with severe hypertriglyceridemia on a normal chow diet X Zhang, R Qi, X Xian, F Yang, M Blackstein, X Deng, J Fan, C Ross, ... Circulation research 102 (2), 250-256, 2008 | 119 | 2008 |
| Deletion of dopamine D1 and D3 receptors differentially affects spontaneous behaviour and cocaine‐induced locomotor activity, reward and CREB phosphorylation JM Karasinska, SR George, R Cheng, BF O'Dowd European Journal of Neuroscience 22 (7), 1741-1750, 2005 | 94 | 2005 |
| Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice MLE MacDonald, N Bissada, P Ruddle, R Watts, JM Karasinska, ... Journal of lipid research 49 (1), 217-229, 2008 | 79 | 2008 |
| ABCA1 influences neuroinflammation and neuronal death JM Karasinska, W de Haan, S Franciosi, P Ruddle, J Fan, JK Kruit, ... Neurobiology of disease 54, 445-455, 2013 | 78 | 2013 |
| Genome-wide synthetic lethal screen unveils novel CAIX-NFS1/xCT axis as a targetable vulnerability in hypoxic solid tumors SC Chafe, FS Vizeacoumar, G Venkateswaran, O Nemirovsky, S Awrey, ... Science advances 7 (35), eabj0364, 2021 | 77 | 2021 |
| Presynaptic defects underlying impaired learning and memory function in lipoprotein lipase-deficient mice X Xian, T Liu, J Yu, Y Wang, Y Miao, J Zhang, Y Yu, C Ross, ... Journal of Neuroscience 29 (14), 4681-4685, 2009 | 70 | 2009 |
| Modification of dopamine D1 receptor knockout phenotype in mice lacking both dopamine D1 and D3 receptors JM Karasinska, SR George, M El-Ghundi, PJ Fletcher, BF O'Dowd European journal of pharmacology 399 (2-3), 171-181, 2000 | 69 | 2000 |
| Clinical and genomic characterisation of mismatch repair deficient pancreatic adenocarcinoma RC Grant, R Denroche, GH Jang, KM Nowak, A Zhang, A Borgida, ... Gut 70 (10), 1894-1903, 2021 | 65 | 2021 |
| Deficiency of brain ATP-binding cassette transporter A-1 exacerbates blood–brain barrier and white matter damage after stroke X Cui, M Chopp, A Zacharek, JM Karasinska, Y Cui, R Ning, Y Zhang, ... Stroke 46 (3), 827-834, 2015 | 49 | 2015 |
| A novel multiplex droplet digital PCR assay to identify and quantify KRAS mutations in clinical specimens M Alcaide, M Cheung, K Bushell, SE Arthur, HL Wong, J Karasinska, ... The Journal of Molecular Diagnostics 21 (2), 214-227, 2019 | 37 | 2019 |
