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Gabriella T Heller
Gabriella T Heller
Verified email at ucl.ac.uk
Title
Cited by
Cited by
Year
Promoting transparency and reproducibility in enhanced molecular simulations
M Bonomi, G Bussi, C Camilloni, GA Tribello, P Banáš, A Barducci, ...
Nature methods 16 (8), 670-673, 2019
6272019
Principles of protein structural ensemble determination
M Bonomi, GT Heller, C Camilloni, M Vendruscolo
Current Opinion in Structural Biology 42, 106-116, 2017
3022017
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity
M Perni, C Galvagnion, A Maltsev, G Meisl, MBD Müller, PK Challa, ...
Proceedings of the National Academy of Sciences 114 (6), E1009-E1017, 2017
2992017
Vocabulary, syntax, and narrative development in typically developing children and children with early unilateral brain injury: Early parental talk about the “there-and-then …
ÖE Demir, ML Rowe, G Heller, S Goldin-Meadow, SC Levine
Developmental psychology 51 (2), 161, 2015
1362015
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes
R Limbocker, S Chia, FS Ruggeri, M Perni, R Cascella, GT Heller, G Meisl, ...
Nature communications 10 (1), 225, 2019
1322019
Simultaneous quantification of protein order and disorder
P Sormanni, D Piovesan, GT Heller, M Bonomi, P Kukic, C Camilloni, ...
Nature chemical biology 13 (4), 339-342, 2017
1172017
Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine
M Perni, P Flagmeier, R Limbocker, R Cascella, FA Aprile, C Galvagnion, ...
ACS chemical biology 13 (8), 2308-2319, 2018
1042018
Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer’s disease
GT Heller, FA Aprile, TCT Michaels, R Limbocker, M Perni, FS Ruggeri, ...
Science advances 6 (45), eabb5924, 2020
1012020
Targeting disordered proteins with small molecules using entropy
GT Heller, P Sormanni, M Vendruscolo
Trends in biochemical sciences 40 (9), 491-496, 2015
992015
Rational design of a conformation-specific antibody for the quantification of Aβ oligomers
FA Aprile, P Sormanni, M Podpolny, S Chhangur, LM Needham, ...
Proceedings of the National Academy of Sciences 117 (24), 13509-13518, 2020
722020
Methods of probing the interactions between small molecules and disordered proteins
GT Heller, FA Aprile, M Vendruscolo
Cellular and Molecular Life Sciences 74, 3225-3243, 2017
652017
Sequence Specificity in the Entropy-Driven Binding of a Small Molecule and a Disordered Peptide
GT Heller, FA Aprile, M Bonomi, C Camilloni, A De Simone, ...
Journal of Molecular Biology 429 (18), 2772-2779, 2017
632017
Structural ensemble modulation upon small-molecule binding to disordered proteins
GT Heller, M Bonomi, M Vendruscolo
Journal of molecular biology 430 (16), 2288-2292, 2018
582018
Structural ensemble modulation upon small-molecule binding to disordered proteins
GT Heller, M Bonomi, M Vendruscolo
Journal of molecular biology 430 (16), 2288-2292, 2018
582018
Determination of Structural Ensembles of Proteins: Restraining vs Reweighting
R Rangan, M Bonomi, GT Heller, A Cesari, G Bussi, M Vendruscolo
Journal of chemical theory and computation 14 (12), 6632-6641, 2018
562018
Thermodynamic and kinetic design principles for amyloid-aggregation inhibitors
TCT Michaels, A Šarić, G Meisl, GT Heller, S Curk, P Arosio, S Linse, ...
Proceedings of the National Academy of Sciences 117 (39), 24251-24257, 2020
542020
Thermodynamic and kinetic design principles for amyloid-aggregation inhibitors
TCT Michaels, A Šarić, G Meisl, GT Heller, S Curk, P Arosio, S Linse, ...
Proceedings of the National Academy of Sciences 117 (39), 24251-24257, 2020
542020
A kinetic ensemble of the Alzheimer’s Aβ peptide
T Löhr, K Kohlhoff, GT Heller, C Camilloni, M Vendruscolo
Nature Computational Science 1 (1), 71-78, 2021
432021
A small molecule stabilizes the disordered native state of the Alzheimer’s Aβ peptide
T Löhr, K Kohlhoff, GT Heller, C Camilloni, M Vendruscolo
ACS Chemical Neuroscience 13 (12), 1738, 2022
192022
A rationally designed bicyclic peptide remodels Aβ42 aggregation in vitro and reduces its toxicity in a worm model of Alzheimer’s disease
T Ikenoue, FA Aprile, P Sormanni, FS Ruggeri, M Perni, GT Heller, ...
Scientific reports 10 (1), 15280, 2020
172020
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