| Lysine glutarylation is a protein posttranslational modification regulated by SIRT5 M Tan, C Peng, KA Anderson, P Chhoy, Z Xie, L Dai, J Park, Y Chen, ... Cell metabolism 19 (4), 605-617, 2014 | 788 | 2014 |
| Lipids reprogram metabolism to become a major carbon source for histone acetylation E McDonnell, SB Crown, DB Fox, B Kitir, OR Ilkayeva, CA Olsen, ... Cell reports 17 (6), 1463-1472, 2016 | 332 | 2016 |
| SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion KA Anderson, FK Huynh, K Fisher-Wellman, JD Stuart, BS Peterson, ... Cell metabolism 25 (4), 838-855. e15, 2017 | 307 | 2017 |
| Class I histone deacetylases (HDAC1–3) are histone lysine delactylases C Moreno-Yruela, D Zhang, W Wei, M Bæk, W Liu, J Gao, D Danková, ... Science advances 8 (3), eabi6696, 2022 | 204 | 2022 |
| Metabolic control by sirtuins and other enzymes that sense NAD+, NADH, or their ratio KA Anderson, AS Madsen, CA Olsen, MD Hirschey Biochimica et Biophysica Acta (BBA)-Bioenergetics 1858 (12), 991-998, 2017 | 199 | 2017 |
| Probing the Bioactive Conformation of an Archetypal Natural Product HDAC Inhibitor with Conformationally Homogeneous Triazole‐Modified Cyclic Tetrapeptides WS Horne, CA Olsen, JM Beierle, A Montero, MR Ghadiri Angewandte Chemie International Edition 48 (26), 4718-4724, 2009 | 180 | 2009 |
| Cis–Trans Amide Bond Rotamers in β-Peptoids and Peptoids: Evaluation of Stereoelectronic Effects in Backbone and Side Chains JS Laursen, J Engel-Andreasen, P Fristrup, P Harris, CA Olsen Journal of the American Chemical Society 135 (7), 2835-2844, 2013 | 150 | 2013 |
| Modular total synthesis of lamellarin D D Pla, A Marchal, CA Olsen, F Albericio, M Álvarez The Journal of Organic Chemistry 70 (20), 8231-8234, 2005 | 146 | 2005 |
| Synthesis and structure− activity relationship study of potent cytotoxic analogues of the marine alkaloid lamellarin D D Pla, A Marchal, CA Olsen, A Francesch, C Cuevas, F Albericio, ... Journal of medicinal chemistry 49 (11), 3257-3268, 2006 | 131 | 2006 |
| Histone deacetylase 11 is an ε-N-myristoyllysine hydrolase C Moreno-Yruela, I Galleano, AS Madsen, CA Olsen Cell chemical biology 25 (7), 849-856. e8, 2018 | 130 | 2018 |
| Profiling of substrates for zinc-dependent lysine deacylase enzymes: HDAC3 exhibits decrotonylase activity in vitro. AS Madsen, CA Olsen Angewandte Chemie (International ed. in English) 51 (36), 9083-9087, 2012 | 124 | 2012 |
| Arylfluorosulfate‐based electrophiles for covalent protein labeling: a new addition to the arsenal P Martín‐Gago, CA Olsen Angewandte Chemie International Edition 58 (4), 957-966, 2019 | 121 | 2019 |
| β-Peptoid foldamers at last JS Laursen, J Engel-Andreasen, CA Olsen Accounts of Chemical Research 48 (10), 2696-2704, 2015 | 113 | 2015 |
| Investigating the sensitivity of NAD+-dependent sirtuin deacylation activities to NADH AS Madsen, C Andersen, M Daoud, KA Anderson, JS Laursen, ... Journal of Biological Chemistry 291 (13), 7128-7141, 2016 | 104 | 2016 |
| α-peptide/β-peptoid chimeras CA Olsen, G Bonke, L Vedel, A Adsersen, M Witt, H Franzyk, ... Organic Letters 9 (8), 1549-1552, 2007 | 103 | 2007 |
| Cross-Talk between Staphylococcus aureus and Other Staphylococcal Species via the agr Quorum Sensing System J Canovas, M Baldry, MS Bojer, PS Andersen, BH Gless, PK Grzeskowiak, ... Frontiers in microbiology 7, 1733, 2016 | 101 | 2016 |
| Design, synthesis, biological evaluation, and structural characterization of potent histone deacetylase inhibitors based on cyclic α/β-tetrapeptide architectures A Montero, JM Beierle, CA Olsen, MR Ghadiri Journal of the American Chemical Society 131 (8), 3033-3041, 2009 | 101 | 2009 |
| Antimicrobial, hemolytic, and cytotoxic activities of β‐peptoid–peptide hybrid oligomers: Improved properties compared to natural AMPs CA Olsen, HL Ziegler, HM Nielsen, N Frimodt‐Møller, JW Jaroszewski, ... ChemBioChem 11 (10), 1356-1360, 2010 | 100 | 2010 |
| Discovery of Potent and Selective Histone Deacetylase Inhibitors via Focused Combinatorial Libraries of Cyclic α3β-Tetrapeptides CA Olsen, MR Ghadiri Journal of medicinal chemistry 52 (23), 7836-7846, 2009 | 99 | 2009 |
| Peptoid–peptide hybrid backbone architectures CA Olsen ChemBioChem 11 (2), 152-160, 2010 | 90 | 2010 |
Henrik FranzykAssociate Professor, Dept. Drug Design and Pharmacology, University of CopenhagenVerified email at sund.ku.dk
