|Differential modulation of antipredator defensive behavior in Swiss-Webster mice following acute or chronic administration of imipramine and fluoxetine|
G Griebel, DC Blanchard, RS Agnes, RJ Blanchard
Psychopharmacology 120 (1), 57-66, 1995
|Conformation–activity relationships of opioid peptides with selective activities at opioid receptors|
VJ Hruby, RS Agnes
Peptide Science 51 (6), 391-410, 1999
|Addressing brain tumors with targeted gold nanoparticles: a new gold standard for hydrophobic drug delivery?|
Y Cheng, JD Meyers, RS Agnes, TL Doane, ME Kenney, AM Broome, ...
Small 7 (16), 2301-2306, 2011
|Neuropathic pain is maintained by brainstem neurons co-expressing opioid and cholecystokinin receptors|
W Zhang, S Gardell, D Zhang, JY Xie, RS Agnes, H Badghisi, VJ Hruby, ...
Brain 132 (3), 778-787, 2009
|Peptide‐Targeted Gold Nanoparticles for Photodynamic Therapy of Brain Cancer|
JD Meyers, Y Cheng, AM Broome, RS Agnes, MD Schluchter, ...
Particle & Particle Systems Characterization 32 (4), 448-457, 2015
|Suborganelle sensing of mitochondrial cAMP-dependent protein kinase activity|
RS Agnes, F Jernigan, JR Shell, V Sharma, DS Lawrence
Journal of the American Chemical Society 132 (17), 6075-6080, 2010
|Deep quench: an expanded dynamic range for protein kinase sensors|
V Sharma, RS Agnes, DS Lawrence
Journal of the American Chemical Society 129 (10), 2742-2743, 2007
|Structure-activity relationships of bifunctional peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors|
RS Agnes, YS Lee, P Davis, S Ma, H Badghisi, F Porreca, J Lai, VJ Hruby
Journal of medicinal chemistry 49 (10), 2868-2875, 2006
|Design of novel peptide ligands which have opioid agonist activity and CCK antagonist activity for the treatment of pain|
VJ Hruby, RS Agnes, P Davis, SW Ma, YS Lee, TW Vanderah, J Lai, ...
Life sciences 73 (6), 699-704, 2003
|Design and synthesis of novel hydrazide-linked bifunctional peptides as δ/μ opioid receptor agonists and CCK-1/CCK-2 receptor antagonists|
YS Lee, RS Agnes, H Badghisi, P Davis, S Ma, J Lai, F Porreca, VJ Hruby
Journal of medicinal chemistry 49 (5), 1773-1780, 2006
|New paradigms and tools in drug design for pain and addiction|
VJ Hruby, F Porreca, HI Yamamura, G Tollin, RS Agnes, YS Lee, M Cai, ...
The AAPS journal 8 (3), E450-E460, 2006
|An optical probe for noninvasive molecular imaging of orthotopic brain tumors overexpressing epidermal growth factor receptor|
RS Agnes, AM Broome, J Wang, A Verma, K Lavik, JP Basilion
Molecular cancer therapeutics 11 (10), 2202-2211, 2012
|Novel peptide ligands with dual acting pharmacophores designed for the pathophysiology of neuropathic pain|
KE Hanlon, DS Herman, RS Agnes, TM Largent-Milnes, IR Kumarasinghe, ...
Brain research 1395, 1-11, 2011
|Photochemically-activated probes of protein-protein interactions|
SK Nandy, RS Agnes, DS Lawrence
Organic letters 9 (12), 2249-2252, 2007
|Understanding the structural requirements of 4-anilidopiperidine analogues for biological activities at μ and δ opioid receptors|
YS Lee, J Nyberg, S Moye, RS Agnes, P Davis, S Ma, J Lai, F Porreca, ...
Bioorganic & medicinal chemistry letters 17 (8), 2161-2165, 2007
|Partial retro-inverso, retro, and inverso modifications of hydrazide linked bifunctional peptides for opioid and cholecystokinin (CCK) receptors|
YS Lee, RS Agnes, P Davis, S Ma, H Badghisi, J Lai, F Porreca, VJ Hruby
Journal of medicinal chemistry 50 (1), 165-168, 2007
|Novel design of bicyclic β-turn dipeptides on solid-phase supports and synthesis of [3.3. 0]-bicyclo [2, 3]-Leu-enkephalin analogues|
X Gu, J Ying, RS Agnes, E Navratilova, P Davis, G Stahl, F Porreca, ...
Organic letters 6 (19), 3285-3288, 2004
|Structure–activity relationships of bifunctional cyclic disulfide peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors|
RS Agnes, J Ying, KE Kövér, YS Lee, P Davis, S Ma, H Badghisi, ...
Peptides 29 (8), 1413-1423, 2008
|Design of peptide agonists.|
VJ Hruby, RS Agnes, C Cai
Methods in enzymology 343, 73, 2002
|Deeply quenched enzyme sensors|
DS Lawrence, V Sharma, RS Agnes
US Patent App. 12/075,118, 2008