| Massively parallel de novo protein design for targeted therapeutics A Chevalier, DA Silva, GJ Rocklin, DR Hicks, R Vergara, P Murapa, ... Nature 550 (7674), 74-79, 2017 | 419 | 2017 |
| Identification and characterization of a novel botulinum neurotoxin S Zhang, G Masuyer, J Zhang, Y Shen, D Lundin, L Henriksson, ... Nature communications 8 (1), 14130, 2017 | 252 | 2017 |
| Identification of a botulinum neurotoxin-like toxin in a commensal strain of Enterococcus faecium S Zhang, F Lebreton, MJ Mansfield, SI Miyashita, J Zhang, ... Cell host & microbe 23 (2), 169-176. e6, 2018 | 149 | 2018 |
| Genetically encoded fluorescent indicators for imaging intracellular potassium ion concentration Y Shen, SY Wu, V Rancic, A Aggarwal, Y Qian, SI Miyashita, K Ballanyi, ... Communications biology 2 (1), 18, 2019 | 117 | 2019 |
| Sulfated glycosaminoglycans and low-density lipoprotein receptor contribute to Clostridium difficile toxin A entry into cells L Tao, S Tian, J Zhang, Z Liu, L Robinson-McCarthy, SI Miyashita, ... Nature microbiology 4 (10), 1760-1769, 2019 | 87 | 2019 |
| Delivery of single-domain antibodies into neurons using a chimeric toxin–based platform is therapeutic in mouse models of botulism SI Miyashita, J Zhang, S Zhang, CB Shoemaker, M Dong Science Translational Medicine 13 (575), eaaz4197, 2021 | 34 | 2021 |
| Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy L Yin, G Masuyer, S Zhang, J Zhang, SI Miyashita, D Burgin, L Lovelock, ... PLoS biology 18 (3), e3000618, 2020 | 19 | 2020 |
| “Non-Toxic” Proteins of the Botulinum Toxin Complex Exert In-vivo Toxicity SI Miyashita, Y Sagane, T Suzuki, T Matsumoto, K Niwa, T Watanabe Scientific reports 6 (1), 31043, 2016 | 18 | 2016 |
| Small-angle X-ray scattering reveals structural dynamics of the botulinum neurotoxin associating protein, nontoxic nonhemagglutinin Y Sagane, SI Miyashita, K Miyata, T Matsumoto, K Inui, S Hayashi, ... Biochemical and biophysical research communications 425 (2), 256-260, 2012 | 18 | 2012 |
| Toxic and nontoxic components of botulinum neurotoxin complex are evolved from a common ancestral zinc protein K Inui, Y Sagane, K Miyata, SI Miyashita, T Suzuki, Y Shikamori, ... Biochemical and biophysical research communications 419 (3), 500-504, 2012 | 17 | 2012 |
| Covalent modifiers of Botulinum neurotoxin counteract toxin persistence M Garland, BM Babin, SI Miyashita, S Loscher, Y Shen, M Dong, M Bogyo ACS chemical biology 14 (1), 76-87, 2018 | 14 | 2018 |
| Sugar-induced conformational change found in the HA-33/HA-17 trimer of the botulinum toxin complex Y Sagane, S Hayashi, T Matsumoto, SI Miyashita, K Inui, K Miyata, ... Biochemical and biophysical research communications 438 (3), 483-487, 2013 | 10 | 2013 |
| Purification and characterization of nontoxic protein complex from serotype D 4947 botulinum toxin complex K Miyata, Y Sagane, K Inui, SI Miyashita, T Suzuki, K Oguma, T Ohyama, ... The Protein Journal 31, 387-392, 2012 | 8 | 2012 |
| Genetically encoded ratiometric indicators for potassium ion Y Shen, SY Wu, V Rancic, Y Qian, SI Miyashita, K Ballanyi, RE Campbell, ... BioRxiv, 254383, 2018 | 7 | 2018 |
| Hemagglutinin gene shuffling among Clostridium botulinum serotypes C and D yields distinct sugar recognition of the botulinum toxin complex K Miyata, T Suzuki, S Hayashi, SI Miyashita, T Ohyama, K Niwa, ... Pathogens and Disease 73 (7), ftv054, 2015 | 7 | 2015 |
| Crystallization and preliminary X-ray analysis of a novel haemagglutinin component of the toxin complex of serotype C Clostridium botulinum S Hayashi, T Akiyama, Y Sagane, SI Miyashita, T Watanabe, S Yajima, ... Acta Crystallographica Section F: Structural Biology Communications 70 (3 …, 2014 | 6 | 2014 |
| Botulinum toxin complex: a delivery vehicle of botulinum neurotoxin traveling digestive tract Y Sagane, K Inui, SI Miyashita, K Miyata, K Niwa, T Watanabe, T Suzuki Structure and Function of Food Engineering. InTech, Rijeka, 137-150, 2012 | 6 | 2012 |
| Crystallization and preliminary X-ray analysis of the Clostridium botulinum type D nontoxic nonhaemagglutinin K Miyata, K Inui, SI Miyashita, Y Sagane, K Hasegawa, T Matsumoto, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2012 | 6 | 2012 |
| Transport of the botulinum neurotoxin–associating protein, nontoxic nonhemagglutinin, across the rat small intestinal epithelial cell monolayer SI Miyashita, Y Sagane, K Niwa, T Watanabe FEMS microbiology letters 346 (1), 73-80, 2013 | 5 | 2013 |
| Random phage display-based screening of peptides that bind to botulinum neurotoxin binding protein, nontoxic nonhemagglutinin Y Sagane, K Miyata, S Kurihara, T Yoneyama, K Inui, SI Miyashita, ... Current microbiology 67, 188-192, 2013 | 4 | 2013 |
