| Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors M Xiao, H Yang, W Xu, S Ma, H Lin, H Zhu, L Liu, Y Liu, C Yang, Y Xu, ... Genes & development 26 (12), 1326-1338, 2012 | 1096 | 2012 |
| Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation H Yang, Y Liu, F Bai, JY Zhang, SH Ma, J Liu, ZD Xu, HG Zhu, ZQ Ling, ... Oncogene 32 (5), 663-669, 2013 | 646 | 2013 |
| IDH1 and IDH2 mutations in tumorigenesis: mechanistic insights and clinical perspectives H Yang, D Ye, KL Guan, Y Xiong Clinical cancer research 18 (20), 5562-5571, 2012 | 479 | 2012 |
| Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas P Wang, Q Dong, C Zhang, PF Kuan, Y Liu, WR Jeck, JB Andersen, ... Oncogene 32 (25), 3091-3100, 2013 | 438 | 2013 |
| Regulation of G 6 PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress YP Wang, LS Zhou, YZ Zhao, SW Wang, LL Chen, LX Liu, ZQ Ling, FJ Hu, ... The EMBO journal 33 (12), 1304-1320, 2014 | 320 | 2014 |
| WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation Y Wang, M Xiao, X Chen, L Chen, Y Xu, L Lv, P Wang, H Yang, S Ma, ... Molecular cell 57 (4), 662-673, 2015 | 307 | 2015 |
| Macrophage ATP-binding cassette transporter A1 overexpression inhibits atherosclerotic lesion progression in low-density lipoprotein receptor knockout mice M Van Eck, RR Singaraja, D Ye, RB Hildebrand, ER James, MR Hayden, ... Arteriosclerosis, thrombosis, and vascular biology 26 (4), 929-934, 2006 | 248 | 2006 |
| SIRT5 desuccinylates and activates pyruvate kinase M2 to block macrophage IL-1β production and to prevent DSS-induced colitis in mice F Wang, K Wang, W Xu, S Zhao, D Ye, Y Wang, Y Xu, L Zhou, Y Chu, ... Cell reports 19 (11), 2331-2344, 2017 | 244 | 2017 |
| SIRT 5 promotes IDH 2 desuccinylation and G6 PD deglutarylation to enhance cellular antioxidant defense L Zhou, F Wang, R Sun, X Chen, M Zhang, Q Xu, Y Wang, S Wang, ... EMBO reports 17 (6), 811-822, 2016 | 231 | 2016 |
| Acetylation of PGK1 promotes liver cancer cell proliferation and tumorigenesis H Hu, W Zhu, J Qin, M Chen, L Gong, L Li, X Liu, Y Tao, H Yin, H Zhou, ... Hepatology 65 (2), 515-528, 2017 | 210 | 2017 |
| Oncometabolite D-2-hydroxyglutarate inhibits ALKBH DNA repair enzymes and sensitizes IDH mutant cells to alkylating agents P Wang, J Wu, S Ma, L Zhang, J Yao, KA Hoadley, MD Wilkerson, ... Cell reports 13 (11), 2353-2361, 2015 | 206 | 2015 |
| Metabolism, activity, and targeting of D-and L-2-hydroxyglutarates D Ye, KL Guan, Y Xiong Trends in cancer 4 (2), 151-165, 2018 | 201 | 2018 |
| SIRT 5 inhibits peroxisomal ACOX 1 to prevent oxidative damage and is downregulated in liver cancer XF Chen, MX Tian, RQ Sun, ML Zhang, LS Zhou, L Jin, LL Chen, WJ Zhou, ... EMBO reports 19 (5), e45124, 2018 | 188 | 2018 |
| SIRT 3‐dependent GOT 2 acetylation status affects the malate–aspartate NADH shuttle activity and pancreatic tumor growth H Yang, L Zhou, Q Shi, Y Zhao, H Lin, M Zhang, S Zhao, Y Yang, ZQ Ling, ... The EMBO journal 34 (8), 1110-1125, 2015 | 185 | 2015 |
| Regulation of cholesterol homeostasis in macrophages and consequences for atherosclerotic lesion development M Pennings, I Meurs, D Ye, R Out, M Hoekstra, TJC Van Berkel, ... FEBS letters 580 (23), 5588-5596, 2006 | 161 | 2006 |
| ATP-binding cassette transporters A1 and G1, HDL metabolism, cholesterol efflux, and inflammation: important targets for the treatment of atherosclerosis D Ye, B Lammers, Y Zhao, I Meurs, T JC Van Berkel, M Van Eck Current drug targets 12 (5), 647-660, 2011 | 157 | 2011 |
| Acetylation negatively regulates glycogen phosphorylase by recruiting protein phosphatase 1 T Zhang, S Wang, Y Lin, W Xu, D Ye, Y Xiong, S Zhao, KL Guan Cell metabolism 15 (1), 75-87, 2012 | 138 | 2012 |
| Destabilization of Fatty Acid Synthase by Acetylation Inhibits De Novo Lipogenesis and Tumor Cell Growth HP Lin, ZL Cheng, RY He, L Song, MX Tian, LS Zhou, BS Groh, WR Liu, ... Cancer research 76 (23), 6924-6936, 2016 | 107 | 2016 |
| Dual-phase stimulated Raman scattering microscopy for real-time two-color imaging R He, Y Xu, L Zhang, S Ma, X Wang, D Ye, M Ji Optica 4 (1), 44-47, 2017 | 104 | 2017 |
| R-2-hydroxyglutarate as the key effector of IDH mutations promoting oncogenesis D Ye, S Ma, Y Xiong, KL Guan Cancer cell 23 (3), 274-276, 2013 | 101 | 2013 |
