Docosahexaenoic acid induces autophagy through p53/AMPK/mTOR signaling and promotes apoptosis in human cancer cells harboring wild-type p53 K Jing, KS Song, S Shin, N Kim, S Jeong, HR Oh, JH Park, KS Seo, ... Autophagy 7 (11), 1348-1358, 2011 | 220 | 2011 |
The omega-3 polyunsaturated fatty acid DHA induces simultaneous apoptosis and autophagy via mitochondrial ROS-mediated Akt-mTOR signaling in prostate cancer cells expressing … S Shin, K Jing, S Jeong, N Kim, KS Song, JY Heo, JH Park, KS Seo, J Han, ... BioMed research international 2013, 2013 | 180 | 2013 |
Pharmacological stimulation of NADH oxidation ameliorates obesity and related phenotypes in mice JH Hwang, DW Kim, EJ Jo, YK Kim, YS Jo, JH Park, SK Yoo, MK Park, ... Diabetes 58 (4), 965-974, 2009 | 149 | 2009 |
p53 as guardian of the mitochondrial genome JH Park, J Zhuang, J Li, PM Hwang FEBS letters 590 (7), 924-934, 2016 | 138 | 2016 |
SIRT2 regulates tumour hypoxia response by promoting HIF-1α hydroxylation KS Seo, JH Park, JY Heo, K Jing, J Han, KN Min, C Kim, GY Koh, K Lim, ... Oncogene 34 (11), 1354-1362, 2015 | 120 | 2015 |
DJ-1 null dopaminergic neuronal cells exhibit defects in mitochondrial function and structure: involvement of mitochondrial complex I assembly JY Heo, JH Park, SJ Kim, KS Seo, JS Han, SH Lee, JM Kim, JI Park, ... PloS one 7 (3), e32629, 2012 | 116 | 2012 |
CRIF1 is essential for the synthesis and insertion of oxidative phosphorylation polypeptides in the mammalian mitochondrial membrane SJ Kim, M Kwon, MJ Ryu, HK Chung, S Tadi, YK Kim, JM Kim, SH Lee, ... Cell metabolism 16 (2), 274-283, 2012 | 113 | 2012 |
Omega-3-polyunsaturated fatty acids suppress pancreatic cancer cell growth in vitro and in vivo via downregulation of Wnt/Beta-catenin signaling KS Song, K Jing, JS Kim, EJ Yun, S Shin, KS Seo, JH Park, JY Heo, ... Pancreatology 11 (6), 574-584, 2012 | 107 | 2012 |
Downregulation of APE1/Ref-1 is involved in the senescence of mesenchymal stem cells JY Heo, K Jing, KS Song, KS Seo, JH Park, JS Kim, YJ Jung, GM Hur, ... Stem cells 27 (6), 1455-1462, 2009 | 78 | 2009 |
Fenofibrate differentially regulates plasminogen activator inhibitor‐1 gene expression via adenosine monophosphate–activated protein kinase–dependent induction of orphan … D Chanda, CH Lee, YH Kim, JR Noh, DK Kim, JH Park, JH Hwang, ... Hepatology 50 (3), 880-892, 2009 | 76 | 2009 |
Rottlerin induces autophagy and apoptotic cell death through a PKC-delta-independent pathway in HT1080 human fibrosarcoma cells: the protective role of autophagy in apoptosis KS Song, JS Kim, EJ Yun, YR Kim, KS Seo, JH Park, YJ Jung, JI Park, ... Autophagy 4 (5), 650-658, 2008 | 71 | 2008 |
Mitochondrial localization and regulation of BRAFV600E in thyroid cancer: a clinically used RAF inhibitor is unable to block the mitochondrial activities of BRAFV600E MH Lee, SE Lee, DW Kim, MJ Ryu, SJ Kim, SJ Kim, YK Kim, JH Park, ... The Journal of Clinical Endocrinology & Metabolism 96 (1), E19-E30, 2011 | 69 | 2011 |
p53 prevents doxorubicin cardiotoxicity independently of its prototypical tumor suppressor activities J Li, P Wang, NA Long, J Zhuang, DA Springer, J Zou, Y Lin, CKE Bleck, ... Proceedings of the National Academy of Sciences 116 (39), 19626-19634, 2019 | 63 | 2019 |
Docosahexaenoic acid-induced apoptosis is mediated by activation of mitogen-activated protein kinases in human cancer cells S Jeong, K Jing, N Kim, S Shin, S Kim, KS Song, JY Heo, JH Park, KS Seo, ... BMC cancer 14, 1-11, 2014 | 62 | 2014 |
Docosahexaenoic acid induces the degradation of HPV E6/E7 oncoproteins by activating the ubiquitin–proteasome system K Jing, S Shin, S Jeong, S Kim, KS Song, JH Park, JY Heo, KS Seo, ... Cell death & disease 5 (11), e1524-e1524, 2014 | 50 | 2014 |
Inhibiting mitochondrial respiration prevents cancer in a mouse model of Li-Fraumeni syndrome P Wang, J Li, FL Walcott, JG Kang, MF Starost, SL Talagala, J Zhuang, ... The Journal of clinical investigation 127 (1), 132-136, 2017 | 47 | 2017 |
Docosahexaenoic acid prevents paraquat-induced reactive oxygen species production in dopaminergic neurons via enhancement of glutathione homeostasis HJ Lee, J Han, Y Jang, SJ Kim, JH Park, KS Seo, S Jeong, S Shin, K Lim, ... Biochemical and biophysical research communications 457 (1), 95-100, 2015 | 42 | 2015 |
An indole derivative protects against acetaminophen-induced liver injury by directly binding to N-acetyl-p-benzoquinone imine in mice JH Park, KS Seo, S Tadi, BH Ahn, JU Lee, JY Heo, J Han, MS Song, ... Antioxidants & redox signaling 18 (14), 1713-1722, 2013 | 40 | 2013 |
The indole derivative NecroX‐7 improves nonalcoholic steatohepatitis in ob/ob mice through suppression of mitochondrial ROS/RNS and inflammation HK Chung, YK Kim, JH Park, MJ Ryu, JY Chang, JH Hwang, CH Lee, ... Liver International 35 (4), 1341-1353, 2015 | 37 | 2015 |
NecroX-7 prevents oxidative stress-induced cardiomyopathy by inhibition of NADPH oxidase activity in rats J Park, E Park, BH Ahn, HJ Kim, J Park, SY Koo, HS Kwak, HS Park, ... Toxicology and applied pharmacology 263 (1), 1-6, 2012 | 37 | 2012 |