| Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling EJ Culp, N Waglechner, W Wang, AA Fiebig-Comyn, YP Hsu, K Koteva, ... Nature 578 (7796), 582-587, 2020 | 208 | 2020 |
| Chemical biology of peptidoglycan acetylation and deacetylation PJ Moynihan, D Sychantha, AJ Clarke Bioorganic Chemistry 54, 44-50, 2014 | 82 | 2014 |
| Mechanistic pathways for peptidoglycan O-acetylation and de-O-acetylation D Sychantha, AS Brott, CS Jones, AJ Clarke Frontiers in Microbiology 9, 412512, 2018 | 50 | 2018 |
| PatB1 is an O-acetyltransferase that decorates secondary cell wall polysaccharides D Sychantha, DJ Little, RN Chapman, GJ Boons, H Robinson, PL Howell, ... Nature chemical biology 14 (1), 79-85, 2018 | 48 | 2018 |
| In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA) D Sychantha, CS Jones, DJ Little, PJ Moynihan, H Robinson, NF Galley, ... PLoS pathogens 13 (10), e1006667, 2017 | 41 | 2017 |
| Accumulation of peptidoglycan O-acetylation leads to altered cell wall biochemistry and negatively impacts pathogenesis factors of Campylobacter jejuni R Ha, E Frirdich, D Sychantha, J Biboy, ME Taveirne, JG Johnson, ... Journal of Biological Chemistry 291 (43), 22686-22702, 2016 | 29 | 2016 |
| Aspergillomarasmine A inhibits metallo-β-lactamases by selectively sequestering Zn2+ D Sychantha, CM Rotondo, KHME Tehrani, NI Martin, GD Wright Journal of Biological Chemistry 297 (2), 2021 | 25 | 2021 |
| Molecular Basis for the Attachment of S-Layer Proteins to the Cell Wall of Bacillus anthracis D Sychantha, RN Chapman, NC Bamford, GJ Boons, PL Howell, ... Biochemistry 57 (13), 1949-1953, 2018 | 24 | 2018 |
| Peptidoglycomics reveals compositional changes in peptidoglycan between biofilm-and planktonic-derived Pseudomonas aeruginosa EM Anderson, D Sychantha, D Brewer, AJ Clarke, J Geddes-McAlister, ... Journal of Biological Chemistry 295 (2), 504-516, 2020 | 23 | 2020 |
| Peptidoglycan Modification by the Catalytic Domain of Streptococcus pneumoniae OatA Follows a Ping-Pong Bi-Bi Mechanism of Action D Sychantha, AJ Clarke Biochemistry 57 (16), 2394-2401, 2018 | 21 | 2018 |
| ClpP inhibitors are produced by a widespread family of bacterial gene clusters EJ Culp, D Sychantha, C Hobson, AC Pawlowski, G Prehna, GD Wright Nature Microbiology 7 (3), 451-462, 2022 | 20 | 2022 |
| Suppression of β-lactam resistance by aspergillomarasmine A is influenced by both the metallo-β-lactamase target and the antibiotic partner CM Rotondo, D Sychantha, K Koteva, GD Wright Antimicrobial Agents and Chemotherapy 64 (4), 10.1128/aac. 01386-19, 2020 | 20 | 2020 |
| O-acetylation of the serine-rich repeat glycoprotein GspB is coordinated with accessory Sec transport R Seepersaud, D Sychantha, BA Bensing, AJ Clarke, PM Sullam PLoS pathogens 13 (8), e1006558, 2017 | 19 | 2017 |
| An ADP-ribosyltransferase toxin kills bacterial cells by modifying structured non-coding RNAs NP Bullen, D Sychantha, SS Thang, PH Culviner, M Rudzite, S Ahmad, ... Molecular Cell 82 (18), 3484-3498. e11, 2022 | 17 | 2022 |
| Structural basis for the O-acetyltransferase function of the extracytoplasmic domain of OatA from Staphylococcus aureus CS Jones, D Sychantha, PL Howell, AJ Clarke Journal of Biological Chemistry 295 (24), 8204-8213, 2020 | 16 | 2020 |
| Assays for the enzymes catalyzing the O-acetylation of bacterial cell wall polysaccharides AS Brott, D Sychantha, AJ Clarke Bacterial Polysaccharides: Methods and Protocols, 115-136, 2019 | 6 | 2019 |
| Identification of a broadly conserved family of enzymes that hydrolyze (p) ppApp S Ahmad, IJ Gordon, KK Tsang, AG Alexei, D Sychantha, J Colautti, ... Proceedings of the National Academy of Sciences 120 (14), e2213771120, 2023 | 4 | 2023 |
| Three-dimensional structure and optimization of the metallo-β-lactamase inhibitor Aspergillomarasmine A K Koteva, D Sychantha, CM Rotondo, C Hobson, JF Britten, GD Wright ACS omega 7 (5), 4170-4184, 2022 | 4 | 2022 |
| Synthesis of lipid-linked precursors of the bacterial cell wall is governed by a feedback control mechanism in Pseudomonas aeruginosa LS Marmont, AK Orta, BWA Baileeves, D Sychantha, ... Nature Microbiology, 1-13, 2024 | | 2024 |
| Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity E Puumala, D Sychantha, E Lach, S Reeves, S Nabeela, M Fogal, ... Cell Chemical Biology, 2024 | | 2024 |
