Isaac Kohane
Isaac Kohane
Harvard Medical School, Children's Hospital, Brigham and Women's Hospital
Verified email at hms.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Cancer Genome Atlas (TCGA) Research Network
Nature 455 (7216), 1061, 2008
58352008
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
ME Patti, AJ Butte, S Crunkhorn, K Cusi, R Berria, S Kashyap, Y Miyazaki, ...
Proceedings of the National Academy of Sciences 100 (14), 8466-8471, 2003
21532003
Gene regulation and DNA damage in the ageing human brain
T Lu, Y Pan, SY Kao, C Li, I Kohane, J Chan, BA Yankner
Nature 429 (6994), 883-891, 2004
18382004
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ...
Nature genetics 50 (5), 668-681, 2018
14152018
Mutual information relevance networks: functional genomic clustering using pairwise entropy measurements
AJ Butte, IS Kohane
Biocomputing 2000, 418-429, 1999
12621999
A mega-analysis of genome-wide association studies for major depressive disorder
Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium
Molecular psychiatry 18 (4), 2013
10762013
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
SL Carter, AC Eklund, IS Kohane, LN Harris, Z Szallasi
Nature genetics 38 (9), 1043-1048, 2006
10432006
Toward precision medicine: building a knowledge network for biomedical research and a new taxonomy of disease
National Research Council
National Academies Press, 2011
966*2011
Machine learning in medicine
A Rajkomar, J Dean, I Kohane
New England Journal of Medicine 380 (14), 1347-1358, 2019
8582019
Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2)
SN Murphy, G Weber, M Mendis, V Gainer, HC Chueh, S Churchill, ...
Journal of the American Medical Informatics Association 17 (2), 124-130, 2010
8172010
Discovering statistically significant pathways in expression profiling studies
L Tian, SA Greenberg, SW Kong, J Altschuler, IS Kohane, PJ Park
Proceedings of the National Academy of Sciences 102 (38), 13544-13549, 2005
7682005
Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks
AJ Butte, P Tamayo, D Slonim, TR Golub, IS Kohane
Proceedings of the National Academy of Sciences 97 (22), 12182-12186, 2000
7452000
Big data and machine learning in health care
AL Beam, IS Kohane
Jama 319 (13), 1317-1318, 2018
7042018
Analysis of matched mRNA measurements from two different microarray technologies
WP Kuo, TK Jenssen, AJ Butte, L Ohno-Machado, IS Kohane
Bioinformatics 18 (3), 405-412, 2002
6032002
Human disease classification in the postgenomic era: a complex systems approach to human pathobiology
J Loscalzo, I Kohane, AL Barabasi
Molecular systems biology 3 (1), 124, 2007
5962007
Artificial intelligence in healthcare
KH Yu, AL Beam, IS Kohane
Nature biomedical engineering 2 (10), 719-731, 2018
5562018
Cluster analysis of gene expression dynamics
MF Ramoni, P Sebastiani, IS Kohane
Proceedings of the National Academy of Sciences 99 (14), 9121-9126, 2002
5392002
Distinctive patterns of microRNA expression in primary muscular disorders
I Eisenberg, A Eran, I Nishino, M Moggio, C Lamperti, AA Amato, ...
Proceedings of the National Academy of Sciences 104 (43), 17016-17021, 2007
5292007
Public standards and patients' control: how to keep electronic medical records accessible but privateMedical information: access and privacyDoctrines for developing electronic …
KD Mandl, D Markwell, R MacDonald, P Szolovits, IS Kohane
Bmj 322 (7281), 283-287, 2001
4872001
The co-morbidity burden of children and young adults with autism spectrum disorders
IS Kohane, A McMurry, G Weber, D MacFadden, L Rappaport, L Kunkel, ...
PloS one 7 (4), e33224, 2012
4792012
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Articles 1–20