| Global analyses of gene expression in early experimental osteoarthritis CTG Appleton, V Pitelka, J Henry, F Beier Arthritis & Rheumatism 56 (6), 1854-1868, 2007 | 299 | 2007 |
| Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis CTG Appleton, DD McErlain, V Pitelka, N Schwartz, SM Bernier, JL Henry, ... Arthritis research & therapy 9, 1-15, 2007 | 202 | 2007 |
| Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis CTG Appleton, DD McErlain, V Pitelka, N Schwartz, SM Bernier, JL Henry, ... Arthritis research & therapy 9, 1-15, 2007 | 201 | 2007 |
| Microarray analyses of gene expression during chondrocyte differentiation identifies novel regulators of hypertrophy CG James, CTG Appleton, V Ulici, TM Underhill, F Beier Molecular biology of the cell 16 (11), 5316-5333, 2005 | 149 | 2005 |
| Rho/ROCK and MEK/ERK activation by transforming growth factor-α induces articular cartilage degradation CTG Appleton, SE Usmani, JS Mort, F Beier Laboratory investigation 90 (1), 20-30, 2010 | 133 | 2010 |
| Osteoarthritis year in review 2017: biology CT Appleton Osteoarthritis and cartilage 26 (3), 296-303, 2018 | 98 | 2018 |
| Study of subchondral bone adaptations in a rodent surgical model of OA using in vivo micro-computed tomography DD McErlain, CTG Appleton, RB Litchfield, V Pitelka, JL Henry, ... Osteoarthritis and cartilage 16 (4), 458-469, 2008 | 97 | 2008 |
| Transforming growth factor α suppression of articular chondrocyte phenotype and Sox9 expression in a rat model of osteoarthritis CTG Appleton, SE Usmani, SM Bernier, T Aigner, F Beier Arthritis & Rheumatism: Official Journal of the American College of …, 2007 | 91 | 2007 |
| ADAMTS-7 forms a positive feedback loop with TNF-α in the pathogenesis of osteoarthritis Y Lai, X Bai, Y Zhao, Q Tian, B Liu, EA Lin, Y Chen, B Lee, CT Appleton, ... Annals of the rheumatic diseases 73 (8), 1575-1584, 2014 | 86 | 2014 |
| F-spondin, a neuroregulatory protein, is up-regulated in osteoarthritis and regulates cartilage metabolism via TGF-β activation MG Attur, GD Palmer, HE Al-Mussawir, M Dave, CC Teixeira, DB Rifkin, ... The FASEB journal 23 (1), 79, 2009 | 69 | 2009 |
| Reduction in disease progression by inhibition of transforming growth factor α–CCL2 signaling in experimental posttraumatic osteoarthritis CTG Appleton, SE Usmani, MA Pest, V Pitelka, JS Mort, F Beier Arthritis & rheumatology 67 (10), 2691-2701, 2015 | 67 | 2015 |
| Molecular and histological analysis of a new rat model of experimental knee osteoarthritis CTG Appleton, DD McERLAIN, JL Henry, DW Holdsworth, F Beier Annals of the New York Academy of Sciences 1117 (1), 165-174, 2007 | 62 | 2007 |
| The pattern recognition receptor CD36 is a chondrocyte hypertrophy marker associated with suppression of catabolic responses and promotion of repair responses to inflammatory … DL Cecil, CTG Appleton, MD Polewski, JS Mort, AM Schmidt, A Bendele, ... The Journal of Immunology 182 (8), 5024-5031, 2009 | 58 | 2009 |
| Regulator of G‐protein signaling (RGS) proteins differentially control chondrocyte differentiation CTG Appleton, CG James, F Beier Journal of cellular physiology 207 (3), 735-745, 2006 | 54 | 2006 |
| Sequencing identifies a distinct signature of circulating microRNAs in early radiographic knee osteoarthritis SA Ali, R Gandhi, P Potla, S Keshavarzi, O Espin-Garcia, K Shestopaloff, ... Osteoarthritis and cartilage 28 (11), 1471-1481, 2020 | 49 | 2020 |
| Osteoarthritis, cerebrovascular dysfunction and the common denominator of inflammation: a narrative review BK Al-Khazraji, CT Appleton, F Beier, TB Birmingham, JK Shoemaker Osteoarthritis and Cartilage 26 (4), 462-470, 2018 | 37 | 2018 |
| Are we missing the target? Are we aiming too low? What are the aerobic exercise prescriptions and their effects on markers of cardiovascular health and systemic inflammation in … JM Schulz, TB Birmingham, HF Atkinson, E Woehrle, CA Primeau, ... British journal of sports medicine 54 (13), 771-775, 2020 | 35 | 2020 |
| Vascular smooth muscle cells as a valvular interstitial cell surrogate in heart valve tissue engineering AJE Appleton, CTG Appleton, DR Boughner, KA Rogers Tissue Engineering Part A 15 (12), 3889-3897, 2009 | 31 | 2009 |
| Association between changes in knee load and effusion-synovitis: evidence of mechano-inflammation in knee osteoarthritis using high tibial osteotomy as a model HF Atkinson, TB Birmingham, CA Primeau, JM Schulz, CT Appleton, ... Osteoarthritis and Cartilage 29 (2), 222-229, 2021 | 23 | 2021 |
| Strength in numbers: growth of Canadian clinician investigator training in the 21st century CT Appleton, J Belrose, MR Ward, FB Young Clinical and Investigative Medicine 36 (4), E163-E169, 2013 | 20 | 2013 |
Frank BeierUniversity of Western OntarioVerified email at uwo.ca
