Michael Brudno
Michael Brudno
Professor of Computer Science, University of Toronto; Director, Centre for Computaitonal Medicine
Verified email at cs.toronto.edu
TitleCited byYear
Genome sequence of the Brown Norway rat yields insights into mammalian evolution
Rat Genome Sequencing Project Consortium
Nature 428 (6982), 493, 2004
19722004
The genetic landscape of a cell
M Costanzo, A Baryshnikova, J Bellay, Y Kim, ED Spear, CS Sevier, ...
science 327 (5964), 425-431, 2010
18312010
ProbCons: Probabilistic consistency-based multiple sequence alignment
CB Do, MSP Mahabhashyam, M Brudno, S Batzoglou
Genome research 15 (2), 330-340, 2005
11862005
LAGAN and Multi-LAGAN: efficient tools for large-scale multiple alignment of genomic DNA
M Brudno, CB Do, GM Cooper, MF Kim, E Davydov, ED Green, A Sidow, ...
Genome research 13 (4), 721-731, 2003
11362003
VISTA: visualizing global DNA sequence alignments of arbitrary length
C Mayor, M Brudno, JR Schwartz, A Poliakov, EM Rubin, KA Frazer, ...
Bioinformatics 16 (11), 1046-1047, 2000
8852000
SHRiMP: accurate mapping of short color-space reads
SM Rumble, P Lacroute, AV Dalca, M Fiume, A Sidow, M Brudno
PLoS computational biology 5 (5), e1000386, 2009
6242009
The Human Phenotype Ontology project: linking molecular biology and disease through phenotype data
S Köhler, SC Doelken, CJ Mungall, S Bauer, HV Firth, I Bailleul-Forestier, ...
Nucleic acids research 42 (D1), D966-D974, 2013
5782013
Computational methods for discovering structural variation with next-generation sequencing
P Medvedev, M Stanciu, M Brudno
Nature methods 6 (11s), S13, 2009
5512009
SnowFlock: rapid virtual machine cloning for cloud computing
HA Lagar-Cavilla, JA Whitney, AM Scannell, P Patchin, SM Rumble, ...
Proceedings of the 4th ACM European conference on Computer systems, 1-12, 2009
4772009
Similarity network fusion for aggregating data types on a genomic scale
B Wang, AM Mezlini, F Demir, M Fiume, Z Tu, M Brudno, B Haibe-Kains, ...
Nature methods 11 (3), 333, 2014
4462014
Active conservation of noncoding sequences revealed by three-way species comparisons
I Dubchak, M Brudno, GG Loots, L Pachter, C Mayor, EM Rubin, ...
Genome research 10 (9), 1304-1306, 2000
3622000
Glocal alignment: finding rearrangements during alignment
M Brudno, S Malde, A Poliakov, CB Do, O Couronne, I Dubchak, ...
Bioinformatics 19 (suppl 1), i54, 2003
3452003
SHRiMP2: sensitive yet practical short read mapping
M David, M Dzamba, D Lister, L Ilie, M Brudno
Bioinformatics 27 (7), 1011-1012, 2011
3382011
The human phenotype ontology in 2017
S Köhler, NA Vasilevsky, M Engelstad, E Foster, J McMurry, S Aymé, ...
Nucleic acids research 45 (D1), D865-D876, 2016
3302016
Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations
P Buczkowicz, C Hoeman, P Rakopoulos, S Pajovic, L Letourneau, ...
Nature genetics 46 (5), 451, 2014
3132014
Fast and sensitive multiple alignment of large genomic sequences
M Brudno, M Chapman, B Göttgens, S Batzoglou, B Morgenstern
BMC bioinformatics 4 (1), 66, 2003
2092003
The Matchmaker Exchange: a platform for rare disease gene discovery
AA Philippakis, DR Azzariti, S Beltran, AJ Brookes, CA Brownstein, ...
Human mutation 36 (10), 915-921, 2015
1932015
Computability of models for sequence assembly
P Medvedev, K Georgiou, G Myers, M Brudno
International Workshop on Algorithms in Bioinformatics, 289-301, 2007
1662007
Detecting copy number variation with mated short reads
P Medvedev, M Fiume, M Dzamba, T Smith, M Brudno
Genome research 20 (11), 1613-1622, 2010
1642010
Characterization of evolutionary rates and constraints in three mammalian genomes
GM Cooper, M Brudno, EA Stone, I Dubchak, S Batzoglou, A Sidow
Genome research 14 (4), 539-548, 2004
1622004
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Articles 1–20