Exosomes are natural carriers of exogenous siRNA to human cells in vitro TA Shtam, RA Kovalev, EY Varfolomeeva, EM Makarov, YV Kil, MV Filatov Cell Communication and Signaling 11, 1-10, 2013 | 514 | 2013 |
Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome EM Makarov, OV Makarova, H Urlaub, M Gentzel, CL Will, M Wilm, ... Science 298 (5601), 2205-2208, 2002 | 450 | 2002 |
Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion C Girard, CL Will, J Peng, EM Makarov, B Kastner, I Lemm, H Urlaub, ... Nature communications 3 (1), 994, 2012 | 275 | 2012 |
Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6· U5 tri‐snRNP formation and pre‐mRNA splicing OV Makarova, EM Makarov, S Liu, HP Vornlocher, R Lührmann The EMBO journal, 2002 | 229 | 2002 |
The 65 and 110 kDa SR‐related proteins of the U4/U6· U5 tri‐snRNP are essential for the assembly of mature spliceosomes OV Makarova, EM Makarov, R Lührmann The EMBO journal, 2001 | 229 | 2001 |
A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing OV Makarova, EM Makarov, H Urlaub, CL Will, M Gentzel, M Wilm, ... The EMBO journal 23 (12), 2381-2391, 2004 | 218 | 2004 |
RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2β and affect splicing JP Venables, DJ Elliott, OV Makarova, EM Makarov, HJ Cooke, IC Eperon Human molecular genetics 9 (5), 685-694, 2000 | 163 | 2000 |
Quantitative study of interaction of deacylated tRNA with Escherichia coli ribosomes: Role of 50 S subunits in formation of the E site SV Kirillov, EM Makarov, YP Semenkov Febs Letters 157 (1), 91-94, 1983 | 133 | 1983 |
Mammalian PRP4 kinase copurifies and interacts with components of both the U5 snRNP and the N-CoR deacetylase complexes G Dellaire, EM Makarov, JJM Cowger, D Longman, HGE Sutherland, ... Molecular and cellular biology 22 (14), 5141-5156, 2002 | 115 | 2002 |
Transcribing of Escherichia coli genes with mutant T7 RNA polymerases: stability of lacZ mRNA inversely correlates with polymerase speed. OV Makarova, EM Makarov, R Sousa, M Dreyfus Proceedings of the National Academy of Sciences 92 (26), 12250-12254, 1995 | 108 | 1995 |
Human U4/U6. U5 and U4atac/U6atac. U5 tri-snRNPs exhibit similar protein compositions C Schneider, CL Will, OV Makarova, EM Makarov, R Lührmann Molecular and cellular biology, 2002 | 103 | 2002 |
Organization of core spliceosomal components U5 snRNA loop I and U4/U6 Di-snRNP within U4/U6. U5 Tri-snRNP as revealed by electron cryomicroscopy B Sander, MM Golas, EM Makarov, H Brahms, B Kastner, R Lührmann, ... Molecular cell 24 (2), 267-278, 2006 | 99 | 2006 |
Three-dimensional structure of a pre-catalytic human spliceosomal complex B D Boehringer, EM Makarov, B Sander, OV Makarova, B Kastner, ... Nature structural & molecular biology 11 (5), 463-468, 2004 | 95 | 2004 |
The human homologue of the yeast splicing factor prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions EM Makarov, OV Makarova, T Achsel, R Lührmann Journal of molecular biology 298 (4), 567-575, 2000 | 84 | 2000 |
The human U5 snRNP 52K protein (CD2BP2) interacts with U5-102K (hPrp6), a U4/U6. U5 tri-snRNP bridging protein, but dissociates upon tri-snRNP formation B Laggerbauer, S Liu, E Makarov, HP Vornlocher, O Makarova, ... Rna 11 (5), 598-608, 2005 | 78 | 2005 |
Functional mammalian spliceosomal complex E contains SMN complex proteins in addition to U1 and U2 snRNPs EM Makarov, N Owen, A Bottrill, OV Makarova Nucleic acids research 40 (6), 2639-2652, 2012 | 69 | 2012 |
Study of gene-targeted mouse models of splicing factor gene Prpf31 implicated in human autosomal dominant retinitis pigmentosa (RP) K Bujakowska, C Maubaret, CF Chakarova, N Tanimoto, SC Beck, E Fahl, ... Investigative ophthalmology & visual science 50 (12), 5927-5933, 2009 | 67 | 2009 |
Isoforms of U1-70k control subunit dynamics in the human spliceosomal U1 snRNP H Hernandez, OV Makarova, EM Makarov, N Morgner, Y Muto, ... PloS one 4 (9), e7202, 2009 | 57 | 2009 |
Kinetic aspects of tetracycline action on the acceptor (A) site of Escherichia coli ribosomes YP Semenkov, EM Makarov, VI Makhno, SV Kirillov FEBS letters 144 (1), 125-129, 1982 | 50 | 1982 |
A novel splice variant of the DNA-PKcs gene is associated with clinical and cellular radiosensitivity in a patient with xeroderma pigmentosum F Abbaszadeh, PH Clingen, CF Arlett, PN Plowman, EC Bourton, ... Journal of medical genetics 47 (3), 176-181, 2010 | 41 | 2010 |