Guidelines and considerations for the use of system suitability and quality control samples in mass spectrometry assays applied in untargeted clinical metabolomic studies D Broadhurst, R Goodacre, SN Reinke, J Kuligowski, ID Wilson, ... Metabolomics 14 (6), 1-17, 2018 | 750 | 2018 |
U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics D Lefaudeux, B De Meulder, MJ Loza, N Peffer, A Rowe, F Baribaud, ... Journal of Allergy and Clinical Immunology 139 (6), 1797-1807, 2017 | 303 | 2017 |
Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS JG Walsh, SN Reinke, MK Mamik, BA McKenzie, F Maingat, WG Branton, ... Retrovirology 11 (1), 1, 2014 | 232 | 2014 |
Metabolomics analysis identifies different metabotypes of asthma severity SN Reinke, H Gallart-Ayala, C Gómez, A Checa, A Fauland, S Naz, ... European Respiratory Journal 49 (3), 1601740, 2017 | 177 | 2017 |
A comparative evaluation of the generalised predictive ability of eight machine learning algorithms across ten clinical metabolomics data sets for binary classification KM Mendez, SN Reinke, DI Broadhurst Metabolomics 15 (12), 1-15, 2019 | 159 | 2019 |
Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study MJ Loza, R Djukanovic, KF Chung, D Horowitz, K Ma, P Branigan, ... Respiratory research 17 (1), 1-21, 2016 | 145 | 2016 |
Development of a Liquid Chromatography–High Resolution Mass Spectrometry Metabolomics Method with High Specificity for Metabolite Identification Using All Ion Fragmentation … S Naz, H Gallart-Ayala, SN Reinke, C Mathon, R Blankley, R Chaleckis, ... Analytical Chemistry 89 (15), 7933-7942, 2017 | 140 | 2017 |
Ubiquinone-binding site mutations in the Saccharomyces cerevisiae succinate dehydrogenase generate superoxide and lead to the accumulation of succinate SSW Szeto, SN Reinke, BD Sykes, BD Lemire Journal of Biological Chemistry 282 (37), 27518-27526, 2007 | 127 | 2007 |
A glycolytic burst drives glucose induction of global histone acetylation by picNuA4 and SAGA RMN Friis, BP Wu, SN Reinke, DJ Hockman, BD Sykes, MC Schultz Nucleic acids research 37 (12), 3969-3980, 2009 | 125 | 2009 |
Caenorhabditis elegans diet significantly affects metabolic profile, mitochondrial DNA levels, lifespan and brood size SN Reinke, X Hu, BD Sykes, BD Lemire Molecular genetics and metabolism 100 (3), 274-282, 2010 | 108 | 2010 |
IL-17–high asthma with features of a psoriasis immunophenotype J Östling, M van Geest, JPR Schofield, Z Jevnikar, S Wilson, J Ward, ... Journal of allergy and clinical immunology 144 (5), 1198-1213, 2019 | 105 | 2019 |
Metabolomic profiling in multiple sclerosis: insights into biomarkers and pathogenesis SN Reinke, DI Broadhurst, BD Sykes, GB Baker, I Catz, KG Warren, ... Multiple Sclerosis Journal 20 (10), 1396-1400, 2014 | 103 | 2014 |
The application of artificial neural networks in metabolomics: a historical perspective KM Mendez, DI Broadhurst, SN Reinke Metabolomics 15 (11), 1-14, 2019 | 98 | 2019 |
Metabolomics analysis identifies sex-associated metabotypes of oxidative stress and the autotaxin–lysoPA axis in COPD S Naz, J Kolmert, M Yang, SN Reinke, MA Kamleh, S Snowden, T Heyder, ... European Respiratory Journal 49 (6), 1602322, 2017 | 91 | 2017 |
1H NMR Derived Metabolomic Profile of Neonatal Asphyxia in Umbilical Cord Serum: Implications for Hypoxic Ischemic Encephalopathy SN Reinke, BH Walsh, GB Boylan, BD Sykes, LC Kenny, DM Murray, ... Journal of proteome research 12 (9), 4230-4239, 2013 | 90 | 2013 |
Toward collaborative open data science in metabolomics using Jupyter Notebooks and cloud computing KM Mendez, L Pritchard, SN Reinke, DI Broadhurst Metabolomics 15 (10), 1-16, 2019 | 83 | 2019 |
Mutations in the Saccharomyces cerevisiae succinate dehydrogenase result in distinct metabolic phenotypes revealed through 1H NMR-based metabolic footprinting SSW Szeto, SN Reinke, BD Sykes, BD Lemire Journal of proteome research 9 (12), 6729-6739, 2010 | 70 | 2010 |
Fecal sample collection methods and time of day impact microbiome composition and short chain fatty acid concentrations J Jones, S Reinke, A Ali, D Palmer, C Christophersen Scientific Reports 11 (1), 13964, 2021 | 54 | 2021 |
Formate can differentiate between hyperhomocysteinemia due to impaired remethylation and impaired transsulfuration SG Lamarre, AM Molloy, SN Reinke, BD Sykes, ME Brosnan, JT Brosnan American Journal of Physiology-Endocrinology and Metabolism 302 (1), E61-E67, 2012 | 49 | 2012 |
Migrating from partial least squares discriminant analysis to artificial neural networks: a comparison of functionally equivalent visualisation and feature contribution tools … KM Mendez, DI Broadhurst, SN Reinke Metabolomics 16 (2), 1-15, 2020 | 45 | 2020 |