| Trinucleotide repeat amplification and hypermethylation of a CpG island in FRAXE mental retardation SJL Knight, AV Flannery, MC Hirst, L Campbell, Z Christodoulou, ... Cell 74 (1), 127-134, 1993 | 664 | 1993 |
| Physical mapping across the fragile X: hypermethylation and clinical expression of the fragile X syndrome MV Bell, MC Hirst, Y Nakahori, RN MacKinnon, A Roche, TJ Flint, ... Cell 64 (4), 861-866, 1991 | 450 | 1991 |
| MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation. MA Lopez-Ramirez, D Wu, G Pryce, JE Simpson, A Reijerkerk, ... FASEB journal 28 (6), 2551-2565, 2014 | 266 | 2014 |
| A microdeletion of less than 250 kb, including the proximal part of the FMR-1 gene and the fragile-X site, in a male with the clinical phenotype of fragile-X syndrome D Wöhrle, D Kotzot, MC Hirst, A Manca, B Korn, A Schmidt, G Barbi, ... American journal of human genetics 51 (2), 299, 1992 | 205 | 1992 |
| Early development of aberrant synaptic plasticity in a mouse model of Huntington's disease AJ Milnerwood, DM Cummings, GM Dallérac, JY Brown, SC Vatsavayai, ... Human molecular genetics 15 (10), 1690-1703, 2006 | 170 | 2006 |
| Instability of a (CGG)98 repeat in the Fmr1 promoter CJM Bontekoe, CE Bakker, IM Nieuwenhuizen, H van Der Linde, H Lans, ... Human molecular genetics 10 (16), 1693-1699, 2001 | 169 | 2001 |
| Precursor arrays for triplet repeat expansion at the fragile X locus MC Hirst, PK Grewal, KE Davies Human Molecular Genetics 3 (9), 1553-1560, 1994 | 168 | 1994 |
| Triplet repeat expansion at the FRAXE locus and X-linked mild mental handicap. SJ Knight, MA Voelckel, MC Hirst, AV Flannery, A Moncla, KE Davies American journal of human genetics 55 (1), 81, 1994 | 151 | 1994 |
| Aberrant cortical synaptic plasticity and dopaminergic dysfunction in a mouse model of Huntington's disease DM Cummings, AJ Milnerwood, GM Dallerac, V Waights, JY Brown, ... Human molecular genetics 15 (19), 2856-2868, 2006 | 127 | 2006 |
| Stability of the Human Fragile X (CGG)n Triplet Repeat Array in Saccharomyces cerevisiae Deficient in Aspects of DNA Metabolism PJ White, RH Borts, MC Hirst Molecular and cellular biology 19 (8), 5675-5684, 1999 | 123 | 1999 |
| Two new cases of FMR1 deletion associated with mental impairment. M Hirst, P Grewal, A Flannery, R Slatter, E Maher, D Barton, JP Fryns, ... American journal of human genetics 56 (1), 67, 1995 | 122 | 1995 |
| Molecular heterogeneity of the fragile X syndrome Y Nakahori, SJL Knight, J Holland, C Schwartz, A Roche, J Tarleton, ... Nucleic acids research 19 (16), 4355-4359, 1991 | 115 | 1991 |
| The identification of a third fragile site, FRAXF, in Xq27—q28 distal to both FRAXA and FRAXE MC Hirst, A Barnicoat, G Flynn, Q Wang, M Daker, VJ Buckle, KE Davies, ... Human molecular genetics 2 (2), 197-200, 1993 | 114 | 1993 |
| Nucleosome assembly on methylated CGG triplet repeats in the fragile X mental retardation gene 1 promoter JS Godde, SU Kass, MC Hirst, AP Wolffe Journal of Biological Chemistry 271 (40), 24325-24328, 1996 | 109 | 1996 |
| Brain endothelial miR-146a negatively modulates T-cell adhesion through repressing multiple targets to inhibit NF-κB activation D Wu, C Cerutti, MA Lopez-Ramirez, G Pryce, J King-Robson, ... Journal of Cerebral Blood Flow & Metabolism 35 (3), 412-423, 2015 | 91 | 2015 |
| The cloning of FRAXF: trinucleotide repeat expansion and methylation at a third fragile site in distal Xqter RJ Ritchie, SJL Knight, MC Hirst, PK Grewal, M Bobrow, GS Cross, ... Human molecular genetics 3 (12), 2115-2121, 1994 | 87 | 1994 |
| Identification of the FRAXE fragile site in two families ascertained for X linked mental retardation. GA Flynn, MC Hirst, SJ Knight, JN Macpherson, JC Barber, AV Flannery, ... Journal of medical genetics 30 (2), 97-100, 1993 | 82 | 1993 |
| Genotype mosaicism in fragile X fetal tissues D Wöhrle, MC Hirst, I Kennerknecht, KE Davies, P Steinbach Human genetics 89, 114-116, 1992 | 80 | 1992 |
| Origins of the fragile X syndrome mutation. MC Hirst, SJ Knight, Z Christodoulou, PK Grewal, JP Fryns, KE Davies Journal of medical genetics 30 (8), 647-650, 1993 | 71 | 1993 |
| Cloned human FMR1 trinucleotide repeats exhibit a length-and orientation-dependent instability suggestive of in vivo lagging strand secondary structure MC Hirst, PJ White Nucleic acids research 26 (10), 2353-2358, 1998 | 69 | 1998 |
Kay DaviesProfessor of Genetics University of OxfordVerified email at dpag.ox.ac.uk
