Best practices and benchmarks for intact protein analysis for top-down mass spectrometry DP Donnelly, CM Rawlins, CJ DeHart, L Fornelli, LF Schachner, Z Lin, ... Nature methods 16 (7), 587-594, 2019 | 314 | 2019 |
Top-down characterization of endogenous protein complexes with native proteomics OS Skinner, NA Haverland, L Fornelli, RD Melani, LHF Do Vale, ... Nature chemical biology 14 (1), 36-41, 2018 | 144 | 2018 |
The biosynthesis of methanobactin GE Kenney, LMK Dassama, ME Pandelia, AS Gizzi, RJ Martinie, P Gao, ... Science 359 (6382), 1411-1416, 2018 | 114 | 2018 |
Native top-down mass spectrometry provides insights into the copper centers of membrane-bound methane monooxygenase SY Ro, LF Schachner, CW Koo, R Purohit, JP Remis, GE Kenney, ... Nature communications 10 (1), 2675, 2019 | 89 | 2019 |
Top-down proteomics: Where we are, where we are going? L Fornelli, TK Toby, LF Schachner, PF Doubleday, K Srzentić, CJ DeHart, ... Journal of proteomics 175, 3, 2018 | 78 | 2018 |
Characterization of chain pairing variants of bispecific IgG expressed in a single host cell by high-resolution native and denaturing mass spectrometry L Schachner, G Han, M Dillon, J Zhou, L McCarty, D Ellerman, Y Yin, ... Analytical chemistry 88 (24), 12122-12127, 2016 | 47 | 2016 |
Individual ion mass spectrometry enhances the sensitivity and sequence coverage of top-down mass spectrometry JO Kafader, KR Durbin, RD Melani, BJ Des Soye, LF Schachner, ... Journal of proteome research 19 (3), 1346-1350, 2020 | 45 | 2020 |
Standard proteoforms and their complexes for native mass spectrometry LF Schachner, AN Ives, JP McGee, RD Melani, JO Kafader, PD Compton, ... Journal of The American Society for Mass Spectrometry 30 (7), 1190-1198, 2019 | 43 | 2019 |
Native vs denatured: an in depth investigation of charge state and isotope distributions JO Kafader, RD Melani, LF Schachner, AN Ives, SM Patrie, NL Kelleher, ... Journal of the American Society for Mass Spectrometry 31 (3), 574-581, 2020 | 39 | 2020 |
Decoding the protein composition of whole nucleosomes with Nuc-MS LF Schachner, K Jooß, MA Morgan, A Piunti, MJ Meiners, JO Kafader, ... Nature methods 18 (3), 303-308, 2021 | 30 | 2021 |
A novel crosslinking protocol stabilizes amyloid β oligomers capable of inducing Alzheimer's‐associated pathologies EN Cline, A Das, MA Bicca, SN Mohammad, LF Schachner, JM Kamel, ... Journal of neurochemistry 148 (6), 822-836, 2019 | 25 | 2019 |
Using 10,000 fragment ions to inform scoring in native top-down proteomics AN Ives, T Su, KR Durbin, BP Early, H dos Santos Seckler, RT Fellers, ... Journal of the American Society for Mass Spectrometry 31 (7), 1398-1409, 2020 | 22 | 2020 |
Separation and characterization of endogenous nucleosomes by native capillary zone electrophoresis–top-down mass spectrometry K Jooß, LF Schachner, R Watson, ZB Gillespie, SA Howard, MA Cheek, ... Analytical chemistry 93 (12), 5151-5160, 2021 | 21 | 2021 |
Repurposed HisC aminotransferases complete the biosynthesis of some methanobactins YJ Park, GE Kenney, LF Schachner, NL Kelleher, AC Rosenzweig Biochemistry 57 (25), 3515-3523, 2018 | 19 | 2018 |
Reassembling protein complexes after controlled disassembly by top-down mass spectrometry in native mode LF Schachner, DP Tran, AS Lee, JP McGee, K Jooss, KR Durbin, ... International journal of mass spectrometry 465, 116591, 2021 | 11 | 2021 |
Revving an engine of human metabolism: activity enhancement of triosephosphate isomerase via hemi-phosphorylation LF Schachner, BD Soye, S Ro, GE Kenney, AN Ives, T Su, YA Goo, ... ACS chemical biology 17 (10), 2769-2780, 2022 | 9 | 2022 |
The search engine for multi‐proteoform complexes: an online tool for the identification and stoichiometry determination of protein complexes OS Skinner, LF Schachner, NL Kelleher Current protocols in bioinformatics 56 (1), 13.30. 1-13.30. 11, 2016 | 8 | 2016 |
Development of novel methods for non-canonical myeloma protein analysis with an innovative adaptation of immunofixation electrophoresis, native top-down mass spectrometry, and … WI Deighan, VJ Winton, RD Melani, LC Anderson, JP McGee, ... Clinical Chemistry and Laboratory Medicine (CCLM) 59 (4), 653-661, 2021 | 6 | 2021 |
High-Throughput, quantitative analysis of peptide-exchanged MHCI Complexes by native mass spectrometry LF Schachner, W Phung, G Han, M Darwish, A Bell, JS Mellors, K Srzentic, ... Analytical Chemistry 94 (42), 14593-14602, 2022 | 4 | 2022 |
Native Proteomics: A new approach to protein complex discovery and characterization PD Compton, O Skinner, N Haverland, L Fornelli, P Doubleday, H Seckler, ... The FASEB Journal 31, 760.2-760.2, 2017 | 4 | 2017 |