Demian Obregon
Demian Obregon
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Stimulation of cannabinoid receptor 2 (CB 2) suppresses microglial activation
J Ehrhart, D Obregon, T Mori, H Hou, N Sun, Y Bai, T Klein, F Fernandez, ...
Journal of neuroinflammation 2 (1), 1-13, 2005
Inflammaging as a prodrome to Alzheimer's disease
B Giunta, F Fernandez, WV Nikolic, D Obregon, E Rrapo, T Town, J Tan
Journal of neuroinflammation 5 (1), 1-15, 2008
ADAM10 activation is required for green tea (–)-epigallocatechin-3-gallate-induced α-secretase cleavage of amyloid precursor protein
DF Obregon, K Rezai-Zadeh, Y Bai, N Sun, H Hou, J Ehrhart, J Zeng, ...
Journal of Biological Chemistry 281 (24), 16419-16427, 2006
Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice
J Tan, T Town, F Crawford, T Mori, A DelleDonne, R Crescentini, ...
Nature neuroscience 5 (12), 1288-1293, 2002
Inhibition of angiogenesis by Aβ peptides
D Paris, K Townsend, A Quadros, J Humphrey, J Sun, S Brem, ...
Angiogenesis 7 (1), 75-85, 2004
Soluble amyloid precursor protein-α modulates β-secretase activity and amyloid-β generation
D Obregon, H Hou, J Deng, B Giunta, J Tian, D Darlington, ...
Nature communications 3 (1), 1-9, 2012
CD40 is expressed and functional on neuronal cells
J Tan, T Town, T Mori, D Obregon, Y Wu, A DelleDonne, A Rojiani, ...
The EMBO journal 21 (4), 643-652, 2002
The immunology of traumatic brain injury: a prime target for Alzheimer’s disease prevention
B Giunta, D Obregon, R Velisetty, PR Sanberg, CV Borlongan, J Tan
Journal of neuroinflammation 9 (1), 1-8, 2012
Antiretroviral medications disrupt microglial phagocytosis of β-amyloid and increase its production by neurons: implications for HIV-associated neurocognitive disorders
B Giunta, J Ehrhart, DF Obregon, L Lam, L Le, JJ Jin, F Fernandez, J Tan, ...
Molecular brain 4 (1), 1-6, 2011
p35/Cdk5 pathway mediates soluble amyloid‐β peptide‐induced tau phosphorylation in vitro
T Town, J Zolton, R Shaffner, B Schnell, R Crescentini, Y Wu, J Zeng, ...
Journal of neuroscience research 69 (3), 362-372, 2002
Flavonoid‐mediated presenilin‐1 phosphorylation reduces Alzheimer's disease β‐amyloid production
K Rezai‐Zadeh, R Douglas Shytle, Y Bai, J Tian, H Hou, T Mori, J Zeng, ...
Journal of cellular and molecular medicine 13 (3), 574-588, 2009
Proinflammatory and vasoactive effects of Aβ in the cerebrovasculature
KP Townsend, D Obregon, A Quadros, N Patel, CH Volmar, D Paris, ...
Annals of the New York Academy of Sciences 977 (1), 65-76, 2002
Characterization of murine immunoglobulin G antibodies against human amyloid-β1–42
T Town, J Tan, N Sansone, D Obregon, T Klein, M Mullan
Neuroscience letters 307 (2), 101-104, 2001
Peripheral biomarkers in autism: secreted amyloid precursor protein-α as a probable key player in early diagnosis
AR Bailey, BN Giunta, D Obregon, WV Nikolic, J Tian, CD Sanberg, ...
International journal of clinical and experimental medicine 1 (4), 338, 2008
CD45 deficiency drives amyloid-β peptide oligomers and neuronal loss in Alzheimer's disease mice
Y Zhu, H Hou, K Rezai-Zadeh, B Giunta, A Ruscin, C Gemma, JJ Jin, ...
Journal of Neuroscience 31 (4), 1355-1365, 2011
EGCG functions through estrogen receptor-mediated activation of ADAM10 in the promotion of non-amyloidogenic processing of APP
JW Fernandez, K Rezai-Zadeh, D Obregon, J Tan
FEBS letters 584 (19), 4259-4267, 2010
Transcutaneous β-amyloid immunization reduces cerebral β-amyloid deposits without T cell infiltration and microhemorrhage
WV Nikolic, Y Bai, D Obregon, H Hou, T Mori, J Zeng, J Ehrhart, RD Shytle, ...
Proceedings of the National Academy of Sciences 104 (7), 2507-2512, 2007
EGCG mitigates neurotoxicity mediated by HIV-1 proteins gp120 and Tat in the presence of IFN-γ: Role of JAK/STAT1 signaling and implications for HIV-associated dementia
B Giunta, D Obregon, H Hou, J Zeng, N Sun, V Nikolic, J Ehrhart, D Shytle, ...
Brain research 1123 (1), 216-225, 2006
Luteolin reduces Alzheimer’s disease pathologies induced by traumatic brain injury
D Sawmiller, S Li, M Shahaduzzaman, AJ Smith, D Obregon, B Giunta, ...
International journal of molecular sciences 15 (1), 895-904, 2014
Rosiglitazone reduces serum homocysteine levels, smooth muscle proliferation, and intimal hyperplasia in Sprague-Dawley rats fed a high methionine diet
SN Murthy, DF Obregon, NN Chattergoon, NA Fonseca, D Mondal, ...
Metabolism 54 (5), 645-652, 2005
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