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Thomas Wood
Thomas Wood
Sr. Scientist HTS, Enamine
Verified email at enamine.net
Title
Cited by
Cited by
Year
Semisynthetic lipopeptides derived from nisin display antibacterial activity and lipid II binding on par with that of the parent compound
T Koopmans, TM Wood, P ’t Hart, LHJ Kleijn, APA Hendrickx, RJL Willems, ...
Journal of the american chemical society 137 (29), 9382-9389, 2015
762015
The calcium-dependent lipopeptide antibiotics: structure, mechanism, & medicinal chemistry
TM Wood, NI Martin
MedChemComm 10 (5), 634-646, 2019
512019
A High‐Resolution Crystal Structure that Reveals Molecular Details of Target Recognition by the Calcium‐Dependent Lipopeptide Antibiotic Laspartomycin C
LHJ Kleijn, HC Vlieg, TM Wood, J Sastre Toraño, BJC Janssen, NI Martin
Angewandte Chemie International Edition 56 (52), 16546-16549, 2017
302017
Quantification of protein glycosylation using nanopores
RCA Versloot, FLR Lucas, L Yakovlieva, MJ Tadema, Y Zhang, TM Wood, ...
Nano Letters 22 (13), 5357-5364, 2022
292022
Binding studies reveal phospholipid specificity and its role in the calcium-dependent mechanism of action of daptomycin
I Kotsogianni, TM Wood, FM Alexander, SA Cochrane, NI Martin
ACS Infectious Diseases 7 (9), 2612-2619, 2021
272021
Optimization of Metabolic Oligosaccharide Engineering with Ac4GalNAlk and Ac4GlcNAlk by an Engineered Pyrophosphorylase
A Cioce, G Bineva-Todd, AJ Agbay, J Choi, TM Wood, MF Debets, ...
ACS chemical biology 16 (10), 1961-1967, 2021
272021
Cell-specific bioorthogonal tagging of glycoproteins
A Cioce, B Calle, T Rizou, SC Lowery, VL Bridgeman, KE Mahoney, ...
Nature Communications 13 (1), 6237, 2022
232022
P.’t Hart, LHJ Kleijn, APA Hendrickx, RJL Willems, E. Breukink and NI Martin
T Koopmans, TM Wood
J. Am. Chem. Soc 137, 9382-9389, 2015
182015
De novo identification of lipid II binding lipopeptides with antibacterial activity against vancomycin-resistant bacteria
TM Wood, KHME Tehrani, RM van Harten, M Śleszyńska, IR Rebollo, ...
Chemical science 8 (12), 7991-7997, 2017
172017
The contribution of achiral residues in the laspartomycin family of calcium-dependent lipopeptide antibiotics
TM Wood, K Bertheussen, NI Martin
Organic & Biomolecular Chemistry 18 (3), 514-517, 2020
102020
Mechanistic insights into the C 55-P targeting lipopeptide antibiotics revealed by structure–activity studies and high-resolution crystal structures
TM Wood, MR Zeronian, N Buijs, K Bertheussen, HK Abedian, ...
Chemical Science 13 (10), 2985-2991, 2022
92022
A convenient chemoenzymatic preparation of chimeric macrocyclic peptide antibiotics with potent activity against gram-negative pathogens
TM Wood, CJ Slingerland, NI Martin
Journal of Medicinal Chemistry 64 (15), 10890-10899, 2021
82021
Thrombin-derived peptides potentiate the activity of Gram-positive-specific antibiotics against Gram-negative bacteria
CMJ Wesseling, TM Wood, CJ Slingerland, K Bertheussen, S Lok, ...
Molecules 26 (7), 1954, 2021
82021
The Cell Envelope Stress Response of Bacillus subtilis towards Laspartomycin C
A Diehl, TM Wood, S Gebhard, NI Martin, G Fritz
Antibiotics 9 (11), 729, 2020
72020
Chimeric peptidomimetic antibiotic efficiently neutralizes lipopolysaccharides (LPS) and bacteria-induced activation of RAW macrophages
A Javed, CJ Slingerland, TM Wood, NI Martin, F Broere, MH Weingarth, ...
ACS Infectious Diseases 9 (3), 518-526, 2023
52023
A β-hairpin epitope as novel structural requirement for protein arginine rhamnosylation
L Yakovlieva, TM Wood, J Kemmink, I Kotsogianni, F Koller, J Lassak, ...
Chemical Science 12 (4), 1560-1567, 2021
52021
The plant stress hormone jasmonic acid evokes defensive responses in streptomycetes
A Van der Meij, SS Elsayed, C Du, J Willemse, TM Wood, NI Martin, ...
Applied and Environmental Microbiology 89 (11), e01239-23, 2023
22023
Metabolic Engineering Optimizes Bioorthogonal Glycan Labeling in Living Cells
A Cioce, G Bineva-Todd, AJ Agbay, J Choi, TM Wood, M Debets, ...
22021
Synthetic and Mechanistic Studies with Biologically Active Macrocyclic Peptides
TM Wood
Utrecht University, 2021
2021
Structure-activity studies and high-resolution crystal structures provide new mechanistic insights into C
TM Wood, MR Zeronian, HK Abedian, AV Johnson, NM Pearce, M Lutz, ...
Structural studies on cell surface receptors and lipopeptide antibiotics, 93, 2021
2021
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