Pre-mRNA splicing and human disease NA Faustino, TA Cooper Genes & development 17 (4), 419-437, 2003 | 1594 | 2003 |
RNA and disease TA Cooper, L Wan, G Dreyfuss Cell 136 (4), 777-793, 2009 | 1275 | 2009 |
Splicing in disease: disruption of the splicing code and the decoding machinery GS Wang, TA Cooper Nature Reviews Genetics 8 (10), 749-761, 2007 | 1167 | 2007 |
Disruption of splicing regulated by a CUG-binding protein in myotonic dystrophy AV Philips, LT Timchenko, TA Cooper Science 280 (5364), 737-741, 1998 | 927 | 1998 |
Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy RS Savkur, AV Philips, TA Cooper Nature genetics 29 (1), 40-47, 2001 | 913 | 2001 |
Functional consequences of developmentally regulated alternative splicing A Kalsotra, TA Cooper Nature Reviews Genetics 12 (10), 715-729, 2011 | 655 | 2011 |
Loss of the muscle-specific chloride channel in type 1 myotonic dystrophy due to misregulated alternative splicing N Charlet-B, RS Savkur, G Singh, AV Philips, EA Grice, TA Cooper Molecular cell 10 (1), 45-53, 2002 | 654 | 2002 |
The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo KL Meerbrey, G Hu, JD Kessler, K Roarty, MZ Li, JE Fang, JI Herschkowitz, ... Proceedings of the National Academy of Sciences 108 (9), 3665-3670, 2011 | 635 | 2011 |
RNA-mediated neuromuscular disorders LPW Ranum, TA Cooper Annu. Rev. Neurosci. 29, 259-277, 2006 | 552 | 2006 |
Muscleblind proteins regulate alternative splicing TH Ho, N Charlet‐B, MG Poulos, G Singh, MS Swanson, TA Cooper The EMBO journal 23 (15), 3103-3112, 2004 | 521 | 2004 |
A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart A Kalsotra, X Xiao, AJ Ward, JC Castle, JM Johnson, CB Burge, ... Proceedings of the National Academy of Sciences 105 (51), 20333-20338, 2008 | 513 | 2008 |
The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing AN Ladd, N Charlet-B, TA Cooper Molecular and cellular biology 21 (4), 1285-1296, 2001 | 490 | 2001 |
The pathobiology of splicing AJ Ward, TA Cooper The Journal of Pathology: A Journal of the Pathological Society of Great …, 2010 | 484 | 2010 |
Increased steady-state levels of CUGBP1 in myotonic dystrophy 1 are due to PKC-mediated hyperphosphorylation NM Kuyumcu-Martinez, GS Wang, TA Cooper Molecular cell 28 (1), 68-78, 2007 | 470 | 2007 |
Pre-mRNA splicing in disease and therapeutics RK Singh, TA Cooper Trends in molecular medicine 18 (8), 472-482, 2012 | 469 | 2012 |
Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3′-UTR landscape across seven tumour types Z Xia, LA Donehower, TA Cooper, JR Neilson, DA Wheeler, EJ Wagner, ... Nature communications 5 (1), 5274, 2014 | 411 | 2014 |
The spliceosome is a therapeutic vulnerability in MYC-driven cancer TYT Hsu, LM Simon, NJ Neill, R Marcotte, A Sayad, CS Bland, ... Nature 525 (7569), 384-388, 2015 | 399 | 2015 |
A single cardiac troponin T gene generates embryonic and adult isoforms via developmentally regulated alternate splicing. TA Cooper, CP Ordahl Journal of Biological Chemistry 260 (20), 11140-11148, 1985 | 371 | 1985 |
Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines JC Castle, C Zhang, JK Shah, AV Kulkarni, A Kalsotra, TA Cooper, ... Nature genetics 40 (12), 1416-1425, 2008 | 351 | 2008 |
The regulation of splice-site selection, and its role in human disease TA Cooper, W Mattox The American Journal of Human Genetics 61 (2), 259-266, 1997 | 346 | 1997 |