Thomas A Cooper
Thomas A Cooper
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Cited by
Cited by
Pre-mRNA splicing and human disease
NA Faustino, TA Cooper
Genes & development 17 (4), 419-437, 2003
RNA and disease
TA Cooper, L Wan, G Dreyfuss
Cell 136 (4), 777-793, 2009
Splicing in disease: disruption of the splicing code and the decoding machinery
GS Wang, TA Cooper
Nature Reviews Genetics 8 (10), 749-761, 2007
Disruption of splicing regulated by a CUG-binding protein in myotonic dystrophy
AV Philips, LT Timchenko, TA Cooper
Science 280 (5364), 737-741, 1998
Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy
RS Savkur, AV Philips, TA Cooper
Nature genetics 29 (1), 40-47, 2001
Functional consequences of developmentally regulated alternative splicing
A Kalsotra, TA Cooper
Nature Reviews Genetics 12 (10), 715-729, 2011
Loss of the muscle-specific chloride channel in type 1 myotonic dystrophy due to misregulated alternative splicing
N Charlet-B, RS Savkur, G Singh, AV Philips, EA Grice, TA Cooper
Molecular cell 10 (1), 45-53, 2002
The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo
KL Meerbrey, G Hu, JD Kessler, K Roarty, MZ Li, JE Fang, JI Herschkowitz, ...
Proceedings of the National Academy of Sciences 108 (9), 3665-3670, 2011
RNA-mediated neuromuscular disorders
LPW Ranum, TA Cooper
Annu. Rev. Neurosci. 29, 259-277, 2006
Muscleblind proteins regulate alternative splicing
TH Ho, N Charlet‐B, MG Poulos, G Singh, MS Swanson, TA Cooper
The EMBO journal 23 (15), 3103-3112, 2004
A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart
A Kalsotra, X Xiao, AJ Ward, JC Castle, JM Johnson, CB Burge, ...
Proceedings of the National Academy of Sciences 105 (51), 20333-20338, 2008
The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing
AN Ladd, N Charlet-B, TA Cooper
Molecular and cellular biology 21 (4), 1285-1296, 2001
The pathobiology of splicing
AJ Ward, TA Cooper
The Journal of Pathology: A Journal of the Pathological Society of Great …, 2010
Increased steady-state levels of CUGBP1 in myotonic dystrophy 1 are due to PKC-mediated hyperphosphorylation
NM Kuyumcu-Martinez, GS Wang, TA Cooper
Molecular cell 28 (1), 68-78, 2007
Pre-mRNA splicing in disease and therapeutics
RK Singh, TA Cooper
Trends in molecular medicine 18 (8), 472-482, 2012
Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3′-UTR landscape across seven tumour types
Z Xia, LA Donehower, TA Cooper, JR Neilson, DA Wheeler, EJ Wagner, ...
Nature communications 5 (1), 5274, 2014
The spliceosome is a therapeutic vulnerability in MYC-driven cancer
TYT Hsu, LM Simon, NJ Neill, R Marcotte, A Sayad, CS Bland, ...
Nature 525 (7569), 384-388, 2015
A single cardiac troponin T gene generates embryonic and adult isoforms via developmentally regulated alternate splicing.
TA Cooper, CP Ordahl
Journal of Biological Chemistry 260 (20), 11140-11148, 1985
Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines
JC Castle, C Zhang, JK Shah, AV Kulkarni, A Kalsotra, TA Cooper, ...
Nature genetics 40 (12), 1416-1425, 2008
The regulation of splice-site selection, and its role in human disease
TA Cooper, W Mattox
The American Journal of Human Genetics 61 (2), 259-266, 1997
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