Human primary liver cancer organoids reveal intratumor and interpatient drug response heterogeneity L Li, H Knutsdottir, K Hui, MJ Weiss, J He, B Philosophe, AM Cameron, ... JCI insight 4 (2), 2019 | 200 | 2019 |
Myocardial gene expression signatures in human heart failure with preserved ejection fraction VS Hahn, H Knutsdottir, X Luo, K Bedi, KB Margulies, SM Haldar, ... Circulation 143 (2), 120-134, 2021 | 191 | 2021 |
An expanded universe of cancer targets WC Hahn, JS Bader, TP Braun, A Califano, PA Clemons, BJ Druker, ... Cell 184 (5), 1142-1155, 2021 | 170 | 2021 |
Cancer cells educate natural killer cells to a metastasis-promoting cell state IS Chan, H Knútsdóttir, G Ramakrishnan, V Padmanaban, M Warrier, ... Journal of Cell Biology 219 (9), 2020 | 124 | 2020 |
Mathematical model of macrophage-facilitated breast cancer cells invasion H Knútsdóttir, E Pálsson, L Edelstein-Keshet Journal of theoretical biology 357, 184-199, 2014 | 108 | 2014 |
3-D individual cell based computational modeling of tumor cell–macrophage paracrine signaling mediated by EGF and CSF-1 gradients H Knutsdottir, JS Condeelis, E Palsson Integrative Biology 8 (1), 104-119, 2016 | 38 | 2016 |
Hsa-miR-21-3p associates with breast cancer patient survival and targets genes in tumor suppressive pathways A Amirfallah, H Knutsdottir, A Arason, B Hilmarsdottir, OT Johannsson, ... PloS one 16 (11), e0260327, 2021 | 35 | 2021 |
Inhibition of phosphodiesterase type 9 reduces obesity and cardiometabolic syndrome in mice S Mishra, N Sadagopan, B Dunkerly-Eyring, S Rodriguez, DC Sarver, ... The Journal of Clinical Investigation 131 (21), 2021 | 30 | 2021 |
Polarization and migration in the zebrafish posterior lateral line system H Knutsdottir, C Zmurchok, D Bhaskar, E Palsson, D Dalle Nogare, ... PLoS computational biology 13 (4), e1005451, 2017 | 17 | 2017 |
A methodology for morphological feature extraction and unsupervised cell classification D Bhaskar, D Lee, H Knútsdóttir, C Tan, MH Zhang, P Dean, C Roskelley, ... BioRxiv, 623793, 2019 | 13 | 2019 |
Triple negative breast tumors contain heterogeneous cancer cells expressing distinct KRAS-dependent collective and disseminative invasion programs E Henriet, H Knutsdottir, EM Grasset, M Dunworth, M Haynes, JS Bader, ... Oncogene 42 (10), 737-747, 2023 | 10 | 2023 |
Morphology-guided transcriptomic analysis of human pancreatic cancer organoids reveals microenvironmental signals that enhance invasion YJ Jeong, H Knutsdottir, F Shojaeian, MG Lerner, MF Wissler, E Henriet, ... The Journal of clinical investigation 133 (8), 2023 | 7 | 2023 |
A comprehensive single-cell breast tumor atlas defines epithelial and immune heterogeneity and interactions predicting anti-PD-1 therapy response L Xu, K Saunders, SP Huang, H Knutsdottir, K Martinez-Algarin, I Terrazas, ... Cell Reports Medicine 5 (5), 2024 | 6 | 2024 |
A comprehensive single-cell breast tumor atlas defines cancer epithelial and immune cell heterogeneity and interactions predicting anti-PD-1 therapy response L Xu, K Saunders, H Knutsdottir, K Chen, J Maués, C Hodgdon, ... bioRxiv, 2022.08. 01.501918, 2022 | 5 | 2022 |
PDE9 inhibition activates PPARα to stimulate mitochondrial fat metabolism and reduce cardiometabolic syndrome S Mishra, VS Hahn, N Sadagopan, B Dunkerly-Ering, S Rodriguez, ... bioRxiv, 2021.02. 02.429442, 2021 | 3 | 2021 |
Relationship Between Myocardial NPPB Expression and Serum NT-proBNP in Heart Failure With Preserved Ejection Fraction VS Hahn, H Knutsdottir, TE Peterson, D Kikuchi, S Vungarala, DA Kass, ... Heart Failure, 2024 | 2 | 2024 |
The multi-levelled organization of cell migration: from individual cells to tissues H Knutsdottir University of British Columbia, 2018 | 2 | 2018 |
Myocardial transcriptomics reveal distinct gene expression in human heart failure with preserved ejection fraction VS Hahn, H Knutsdottir, JS Bader, KC Bedi, K Margulies, S Haldar, ... Circulation 140 (Suppl_1), A16227-A16227, 2019 | 1 | 2019 |
490e–Complext Patient Derived Organoids (CPDOS) Modeling for Anti-Cancer Drug Screening L Li, H Knutsdottir, K Hui, MJ Weiss, J He, B Philosophe, A Cameron, ... Gastroenterology 156 (6), S-1508, 2019 | 1 | 2019 |
Computational model of breast cancer cell invasion: exploring the EGF/CSF-1 paracrine signaling between macrophages and tumor cells H Knútsdóttir Simon Fraser University, 2012 | 1 | 2012 |