| The ER membrane protein complex is a transmembrane domain insertase A Guna, N Volkmar, JC Christianson, RS Hegde Science 359 (6374), 470-473, 2018 | 267 | 2018 |
| Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq JM Replogle, RA Saunders, AN Pogson, JA Hussmann, A Lenail, A Guna, ... Cell 185 (14), 2559-2575. e28, 2022 | 240 | 2022 |
| EMC is required to initiate accurate membrane protein topogenesis PJ Chitwood, S Juszkiewicz, A Guna, S Shao, RS Hegde Cell 175 (6), 1507-1519. e16, 2018 | 209 | 2018 |
| Transmembrane domain recognition during membrane protein biogenesis and quality control A Guna, RS Hegde Current Biology 28 (8), R498-R511, 2018 | 110 | 2018 |
| Comparative mapping of the 22q11. 2 deletion region and the potential of simple model organisms A Guna, NJ Butcher, AS Bassett Journal of Neurodevelopmental Disorders 7 (1), 1-16, 2015 | 110 | 2015 |
| Response to clozapine in a clinically identifiable subtype of schizophrenia NJ Butcher, WLA Fung, L Fitzpatrick, A Guna, DM Andrade, AE Lang, ... The British Journal of Psychiatry 206 (6), 484-491, 2015 | 78 | 2015 |
| A highly porous metal-organic framework system to deliver payloads for gene knockdown MH Teplensky, M Fantham, C Poudel, C Hockings, M Lu, A Guna, ... Chem 5 (11), 2926-2941, 2019 | 76 | 2019 |
| Elucidating the diagnostic odyssey of 22q11. 2 deletion syndrome LD Palmer, NJ Butcher, E Boot, KA Hodgkinson, T Heung, EWC Chow, ... American Journal of Medical Genetics Part A 176 (4), 936-944, 2018 | 68 | 2018 |
| MTCH2 is a mitochondrial outer membrane protein insertase A Guna, TA Stevens, AJ Inglis, JM Replogle, TK Esantsi, G Muthukumar, ... Science 378 (6617), 317-322, 2022 | 50 | 2022 |
| Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology A Stangherlin, DCS Wong, S Barbiero, JL Watson, A Zeng, E Seinkmane, ... Nature Communications 12, 2021 | 37 | 2021 |
| WNK1 is an assembly factor for the human ER membrane protein complex T Pleiner, M Hazu, GP Tomaleri, K Januszyk, RS Oania, MJ Sweredoski, ... Molecular cell 81 (13), 2693-2704. e12, 2021 | 32 | 2021 |
| Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors JM Replogle, JL Bonnar, AN Pogson, CR Liem, NK Maier, Y Ding, ... Elife 11, e81856, 2022 | 30 | 2022 |
| Differential modes of orphan subunit recognition for the WRB/CAML complex AJ Inglis, KR Page, A Guna, RM Voorhees Cell Reports 30 (11), 3691-3698. e5, 2020 | 27 | 2020 |
| Macromolecular condensation buffers intracellular water potential JL Watson, E Seinkmane, CT Styles, A Mihut, LK Krüger, KE McNally, ... Nature 623 (7988), 842-852, 2023 | 14 | 2023 |
| Coupled protein quality control during nonsense-mediated mRNA decay AJ Inglis, A Guna, Á Gálvez-Merchán, A Pal, TK Esantsi, HR Keys, ... Journal of Cell Science 136 (10), jcs261216, 2023 | 12 | 2023 |
| A genome-wide optical pooled screen reveals regulators of cellular antiviral responses RJ Carlson, MD Leiken, A Guna, N Hacohen, PC Blainey Proceedings of the National Academy of Sciences 120 (16), e2210623120, 2023 | 10 | 2023 |
| A TAle of two pathways: Tail-anchored protein insertion at the endoplasmic reticulum A Guna, M Hazu, GP Tomaleri, RM Voorhees Cold Spring Harbor Perspectives in Biology 15 (3), a041252, 2023 | 9 | 2023 |
| A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens A Guna, KR Page, JM Replogle, TK Esantsi, ML Wang, JS Weissman, ... BMC genomics 24 (1), 651, 2023 | 4 | 2023 |
| Triaging of α-helical proteins to the mitochondrial outer membrane by distinct chaperone machinery based on substrate topology G Muthukumar, TA Stevens, AJ Inglis, TK Esantsi, RA Saunders, F Schulte, ... Molecular Cell, 2024 | | 2024 |
| Role of a holo-insertase complex in the biogenesis of biophysically diverse ER membrane proteins KR Page, VN Nguyen, T Pleiner, GP Tomaleri, ML Wang, A Guna, ... bioRxiv, 2023.11. 28.569054, 2023 | | 2023 |
