SARS-CoV-2 D614G spike mutation increases entry efficiency with enhanced ACE2-binding affinity S Ozono, Y Zhang, H Ode, K Sano, TS Tan, K Imai, K Miyoshi, ... Nature communications 12 (1), 848, 2021 | 419 | 2021 |
Deaminase-independent inhibition of HIV-1 reverse transcription by APOBEC3G Y Iwatani, DSB Chan, F Wang, K Stewart-Maynard, W Sugiura, ... Nucleic acids research 35 (21), 7096-7108, 2007 | 376 | 2007 |
Biochemical activities of highly purified, catalytically active human APOBEC3G: correlation with antiviral effect Y Iwatani, H Takeuchi, K Strebel, JG Levin Journal of virology 80 (12), 5992-6002, 2006 | 235 | 2006 |
The APOBEC3C crystal structure and the interface for HIV-1 Vif binding S Kitamura, H Ode, M Nakashima, M Imahashi, Y Naganawa, T Kurosawa, ... Nature structural & molecular biology 19 (10), 1005-1010, 2012 | 184 | 2012 |
Glycyrrhizin enhances interleukin‐12 production in peritoneal macrophages JH Dai, Y Iwatani, T Ishida, H Terunuma, H Kasai, Y Iwakula, H Fujiwara, ... Immunology 103 (2), 235-243, 2001 | 140 | 2001 |
Monomeric APOBEC3G is catalytically active and has antiviral activity S Opi, H Takeuchi, S Kao, MA Khan, E Miyagi, R Goila-Gaur, Y Iwatani, ... Journal of virology 80 (10), 4673-4682, 2006 | 115 | 2006 |
HIV-2 CRF01_AB: first circulating recombinant form of HIV-2 S Ibe, Y Yokomaku, T Shiino, R Tanaka, J Hattori, S Fujisaki, Y Iwatani, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 54 (3), 241-247, 2010 | 90 | 2010 |
Oligomerization transforms human APOBEC3G from an efficient enzyme to a slowly dissociating nucleic acid-binding protein KR Chaurasiya, MJ McCauley, W Wang, DF Qualley, T Wu, S Kitamura, ... Nature chemistry 6 (1), 28-33, 2014 | 84 | 2014 |
HIV-1 Vif-mediated ubiquitination/degradation of APOBEC3G involves four critical lysine residues in its C-terminal domain Y Iwatani, DSB Chan, L Liu, H Yoshii, J Shibata, N Yamamoto, JG Levin, ... Proceedings of the National Academy of Sciences 106 (46), 19539-19544, 2009 | 75 | 2009 |
Structural insights into HIV-1 Vif-APOBEC3F interaction M Nakashima, H Ode, T Kawamura, S Kitamura, Y Naganawa, H Awazu, ... Journal of virology 90 (2), 1034-1047, 2016 | 71 | 2016 |
Efficient Initiation of HIV-1 Reverse Transcriptionin Vitro: REQUIREMENT FOR RNA SEQUENCES DOWNSTREAM OF THE PRIMER BINDING SITE ABROGATED BY NUCLEOCAPSID PROTEIN-DEPENDENT … Y Iwatani, AE Rosen, J Guo, K Musier-Forsyth, JG Levin Journal of Biological Chemistry 278 (16), 14185-14195, 2003 | 65 | 2003 |
Quasispecies analyses of the HIV-1 near-full-length genome with Illumina MiSeq H Ode, M Matsuda, K Matsuoka, A Hachiya, J Hattori, Y Kito, Y Yokomaku, ... Frontiers in microbiology 6, 1258, 2015 | 60 | 2015 |
APOBEC3G-mediated G-to-A hypermutation of the HIV-1 genome: the missing link in antiviral molecular mechanisms A Okada, Y Iwatani Frontiers in microbiology 7, 240672, 2016 | 59 | 2016 |
Naturally mutated spike proteins of SARS-CoV-2 variants show differential levels of cell entry S Ozono, Y Zhang, H Ode, TS Tan, K Imai, K Miyoshi, S Kishigami, ... BioRxiv, 2020.06. 15.151779, 2020 | 56 | 2020 |
Structural features of antiviral APOBEC3 proteins are linked to their functional activities S Kitamura, H Ode, Y Iwatani Frontiers in microbiology 2, 258, 2011 | 56 | 2011 |
Outbreak of infections by hepatitis B virus genotype A and transmission of genetic drug resistance in patients coinfected with HIV-1 in Japan S Fujisaki, Y Yokomaku, T Shiino, T Koibuchi, J Hattori, S Ibe, Y Iwatani, ... Journal of Clinical Microbiology 49 (3), 1017-1024, 2011 | 52 | 2011 |
Generation of rhesus macaque-tropic HIV-1 clones that are resistant to major anti-HIV-1 restriction factors M Nomaguchi, M Yokoyama, K Kono, EE Nakayama, T Shioda, N Doi, ... Journal of Virology 87 (21), 11447-11461, 2013 | 48 | 2013 |
Impact of long-term antiretroviral therapy on gut and oral microbiotas in HIV-1-infected patients M Imahashi, H Ode, A Kobayashi, M Nemoto, M Matsuda, C Hashiba, ... Scientific reports 11 (1), 960, 2021 | 42 | 2021 |
Antiviral mechanism and biochemical basis of the human APOBEC3 family M Imahashi, M Nakashima, Y Iwatani Frontiers in microbiology 3, 250, 2012 | 42 | 2012 |
Antibody-like proteins that capture and neutralize SARS-CoV-2 T Kondo, Y Iwatani, K Matsuoka, T Fujino, S Umemoto, Y Yokomaku, ... Science advances 6 (42), eabd3916, 2020 | 40 | 2020 |