Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells UE Martinez-Outschoorn, AF Goldberg, Z Lin, YH Ko, N Flomenberg, ... Cancer biology & therapy 12 (10), 924-938, 2011 | 209 | 2011 |
Glutamine fuels a vicious cycle of autophagy in the tumor stroma and oxidative mitochondrial metabolism in epithelial cancer cells: implications for preventing chemotherapy … YH Ko, Z Lin, N Flomenberg, RG Pestell, A Howell, F Sotgia, MP Lisanti, ... Cancer biology & therapy 12 (12), 1085-1097, 2011 | 173 | 2011 |
Understanding the metabolic basis of drug resistance: therapeutic induction of the Warburg effect kills cancer cells UE Martinez-Outschoorn, Z Lin, YH Ko, A Goldberg, N Flomenberg, ... Cell Cycle 10 (15), 2521-2528, 2011 | 114 | 2011 |
Dietary antioxidants protect hematopoietic cells and improve animal survival after total-body irradiation C Wambi, J Sanzari, XS Wan, M Nuth, J Davis, YH Ko, CM Sayers, ... Radiation research 169 (4), 384-396, 2008 | 111 | 2008 |
Oncogenes and inflammation rewire host energy metabolism in the tumor microenvironment: RAS and NFκB target stromal MCT4 UE Martinez-Outschoorn, JM Curry, YH Ko, Z Lin, M Tuluc, D Cognetti, ... Cell cycle 12 (16), 2580-2597, 2013 | 89 | 2013 |
TP53-inducible glycolysis and apoptosis regulator (TIGAR) metabolically reprograms carcinoma and stromal cells in breast cancer YH Ko, M Domingo-Vidal, M Roche, Z Lin, D Whitaker-Menezes, E Seifert, ... Journal of biological chemistry 291 (51), 26291-26303, 2016 | 72 | 2016 |
Heme and hemoglobin utilization by Mycobacterium tuberculosis A Mitra, YH Ko, G Cingolani, M Niederweis Nature communications 10 (1), 4260, 2019 | 70 | 2019 |
Recognition of the TDP-43 nuclear localization signal by importin α1/β SG Doll, H Meshkin, AJ Bryer, F Li, YH Ko, RK Lokareddy, RE Gillilan, ... Cell reports 39 (13), 2022 | 27 | 2022 |
Learning from nature: from a marine natural product to synthetic cyclooxygenase‐1 inhibitors by automated de novo design L Friedrich, G Cingolani, YH Ko, M Iaselli, M Miciaccia, MG Perrone, ... Advanced science 8 (16), 2100832, 2021 | 17 | 2021 |
A periplasmic cinched protein is required for siderophore secretion and virulence of Mycobacterium tuberculosis L Zhang, JE Kent, M Whitaker, DC Young, D Herrmann, AE Aleshin, ... Nature Communications 13 (1), 2255, 2022 | 11 | 2022 |
Recognition of an α-helical hairpin in P22 large terminase by a synthetic antibody fragment RK Lokareddy, YH Ko, N Hong, SG Doll, M Paduch, M Niederweis, ... Acta Crystallographica Section D: Structural Biology 76 (9), 876-888, 2020 | 5 | 2020 |
TP53 Induced Glycolysis and Apoptosis Regulator and Monocarboxylate Transporter 4 drive metabolic reprogramming with c‐MYC and NFkB activation in breast cancer ME Roche, YH Ko, M Domingo‐Vidal, Z Lin, D Whitaker‐Menezes, ... International Journal of Cancer 153 (9), 1671-1683, 2023 | 4 | 2023 |
Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core R Yang, YH Ko, F Li, RK Lokareddy, CFD Hou, C Kim, S Klein, ... Science Advances 10 (2), eadi7606, 2024 | 1 | 2024 |
Metabolic heterogeneity in breast cancer YH Ko Thomas Jefferson University, 2016 | | 2016 |
Understanding the role of mitochondria in the progression from normal fibroblasts to DCIS associated fibroblasts YH Ko, Z Lin, UE Martinez Outschoorn Cancer Research 75 (15_Supplement), 4024-4024, 2015 | | 2015 |
Abstract P3-01-06: TIGAR induces two compartment metabolic coupling and tamoxifen resistance YH Ko, A Bombonati, UE Martinez-Outschoorn Cancer Research 73 (24_Supplement), P3-01-06-P3-01-06, 2013 | | 2013 |