ian Clarke
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Identification of human brain tumour initiating cells
SK Singh, C Hawkins, ID Clarke, JA Squire, J Bayani, T Hide, ...
nature 432 (7015), 396-401, 2004
Identification of a cancer stem cell in human brain tumors
SK Singh, ID Clarke, M Terasaki, VE Bonn, C Hawkins, J Squire, PB Dirks
Cancer research 63 (18), 5821-5828, 2003
Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens
SM Pollard, K Yoshikawa, ID Clarke, D Danovi, S Stricker, R Russell, ...
Cell stem cell 4 (6), 568-580, 2009
Cancer stem cells in nervous system tumors
SK Singh, ID Clarke, T Hide, PB Dirks
Oncogene 23 (43), 7267-7273, 2004
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ...
Nature 506 (7489), 445-450, 2014
Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity
M Meyer, J Reimand, X Lan, R Head, X Zhu, M Kushida, J Bayani, ...
Proceedings of the National Academy of Sciences 112 (3), 851-856, 2015
Frequent amplification of a chr19q13. 41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors
M Li, KF Lee, Y Lu, I Clarke, D Shih, C Eberhart, VP Collins, T Van Meter, ...
Cancer cell 16 (6), 533-546, 2009
Quiescent Sox2+ cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma
RJ Vanner, M Remke, M Gallo, HJ Selvadurai, F Coutinho, L Lee, ...
Cancer cell 26 (1), 33-47, 2014
Multipotent CD15+ cancer stem cells in patched-1–deficient mouse medulloblastoma
RJ Ward, L Lee, K Graham, T Satkunendran, K Yoshikawa, E Ling, ...
Cancer research 69 (11), 4682-4690, 2009
Chemical genetics reveals a complex functional ground state of neural stem cells
P Diamandis, J Wildenhain, ID Clarke, AG Sacher, J Graham, DS Bellows, ...
Nature chemical biology 3 (5), 268-273, 2007
A human brain tumor-derived PDGFR-α deletion mutant is transforming
ID Clarke, PB Dirks
Oncogene 22 (5), 722-733, 2003
Inhibition of dopamine receptor D4 impedes autophagic flux, proliferation, and survival of glioblastoma stem cells
S Dolma, HJ Selvadurai, X Lan, L Lee, M Kushida, V Voisin, H Whetstone, ...
Cancer cell 29 (6), 859-873, 2016
ASCL1 reorganizes chromatin to direct neuronal fate and suppress tumorigenicity of glioblastoma stem cells
NI Park, P Guilhamon, K Desai, RF McAdam, E Langille, M O’Connor, ...
Cell stem cell 21 (2), 209-224. e7, 2017
MLL5 orchestrates a cancer self-renewal state by repressing the histone variant H3. 3 and globally reorganizing chromatin
M Gallo, FJ Coutinho, RJ Vanner, T Gayden, SC Mack, A Murison, ...
Cancer cell 28 (6), 715-729, 2015
MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapy
M Rastegar, A Hotta, P Pasceri, M Makarem, AYL Cheung, S Elliott, ...
PloS one 4 (8), e6810, 2009
Nedd4‐1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function
A Persaud, P Alberts, M Hayes, S Guettler, I Clarke, F Sicheri, P Dirks, ...
The EMBO journal 30 (16), 3259-3273, 2011
A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas
S Agnihotri, A Wolf, DM Munoz, CJ Smith, A Gajadhar, A Restrepo, ...
Journal of Experimental Medicine 208 (4), 689-702, 2011
Localization of intravenously administered verocytotoxins (Shiga-like toxins) 1 and 2 in rabbits immunized with homologous and heterologous toxoids and toxin subunits
M Bielaszewska, I Clarke, MA Karmali, M Petric
Infection and immunity 65 (7), 2509-2516, 1997
A tumorigenic MLL-homeobox network in human glioblastoma stem cells
M Gallo, J Ho, FJ Coutinho, R Vanner, L Lee, R Head, EKM Ling, ...
Cancer research 73 (1), 417-427, 2013
Neural tumor-initiating cells have distinct telomere maintenance and can be safely targeted for telomerase inhibition
P Castelo-Branco, C Zhang, T Lipman, M Fujitani, L Hansford, I Clarke, ...
Clinical Cancer Research 17 (1), 111-121, 2011
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