| Identification of human brain tumour initiating cells SK Singh, C Hawkins, ID Clarke, JA Squire, J Bayani, T Hide, ... nature 432 (7015), 396-401, 2004 | 9199 | 2004 |
| Identification of a cancer stem cell in human brain tumors SK Singh, ID Clarke, M Terasaki, VE Bonn, C Hawkins, J Squire, PB Dirks Cancer research 63 (18), 5821-5828, 2003 | 6875 | 2003 |
| Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens SM Pollard, K Yoshikawa, ID Clarke, D Danovi, S Stricker, R Russell, ... Cell stem cell 4 (6), 568-580, 2009 | 1141 | 2009 |
| Cancer stem cells in nervous system tumors SK Singh, ID Clarke, T Hide, PB Dirks Oncogene 23 (43), 7267-7273, 2004 | 950 | 2004 |
| Epigenomic alterations define lethal CIMP-positive ependymomas of infancy SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ... Nature 506 (7489), 445-450, 2014 | 630 | 2014 |
| Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity M Meyer, J Reimand, X Lan, R Head, X Zhu, M Kushida, J Bayani, ... Proceedings of the National Academy of Sciences 112 (3), 851-856, 2015 | 413 | 2015 |
| Quiescent Sox2+ cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma RJ Vanner, M Remke, M Gallo, HJ Selvadurai, F Coutinho, L Lee, ... Cancer cell 26 (1), 33-47, 2014 | 307 | 2014 |
| Frequent amplification of a chr19q13. 41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors M Li, KF Lee, Y Lu, I Clarke, D Shih, C Eberhart, VP Collins, T Van Meter, ... Cancer cell 16 (6), 533-546, 2009 | 274 | 2009 |
| ASCL1 reorganizes chromatin to direct neuronal fate and suppress tumorigenicity of glioblastoma stem cells NI Park, P Guilhamon, K Desai, RF McAdam, E Langille, M O’Connor, ... Cell stem cell 21 (2), 209-224. e7, 2017 | 217 | 2017 |
| Multipotent CD15+ cancer stem cells in patched-1–deficient mouse medulloblastoma RJ Ward, L Lee, K Graham, T Satkunendran, K Yoshikawa, E Ling, ... Cancer research 69 (11), 4682-4690, 2009 | 209 | 2009 |
| Inhibition of dopamine receptor D4 impedes autophagic flux, proliferation, and survival of glioblastoma stem cells S Dolma, HJ Selvadurai, X Lan, L Lee, M Kushida, V Voisin, H Whetstone, ... Cancer cell 29 (6), 859-873, 2016 | 191 | 2016 |
| Chemical genetics reveals a complex functional ground state of neural stem cells P Diamandis, J Wildenhain, ID Clarke, AG Sacher, J Graham, DS Bellows, ... Nature chemical biology 3 (5), 268-273, 2007 | 179 | 2007 |
| A human brain tumor-derived PDGFR-α deletion mutant is transforming ID Clarke, PB Dirks Oncogene 22 (5), 722-733, 2003 | 143 | 2003 |
| MLL5 orchestrates a cancer self-renewal state by repressing the histone variant H3. 3 and globally reorganizing chromatin M Gallo, FJ Coutinho, RJ Vanner, T Gayden, SC Mack, A Murison, ... Cancer cell 28 (6), 715-729, 2015 | 108 | 2015 |
| MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapy M Rastegar, A Hotta, P Pasceri, M Makarem, AYL Cheung, S Elliott, ... PloS one 4 (8), e6810, 2009 | 100 | 2009 |
| A tumorigenic MLL-homeobox network in human glioblastoma stem cells M Gallo, J Ho, FJ Coutinho, R Vanner, L Lee, R Head, EKM Ling, ... Cancer research 73 (1), 417-427, 2013 | 97 | 2013 |
| Nedd4‐1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function A Persaud, P Alberts, M Hayes, S Guettler, I Clarke, F Sicheri, P Dirks, ... The EMBO journal 30 (16), 3259-3273, 2011 | 97 | 2011 |
| Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells N Rajakulendran, KJ Rowland, HJ Selvadurai, M Ahmadi, NI Park, ... Genes & development 33 (9-10), 498-510, 2019 | 95 | 2019 |
| A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas S Agnihotri, A Wolf, DM Munoz, CJ Smith, A Gajadhar, A Restrepo, ... Journal of Experimental Medicine 208 (4), 689-702, 2011 | 93 | 2011 |
| ATM regulates 3-methylpurine-DNA glycosylase and promotes therapeutic resistance to alkylating agents S Agnihotri, K Burrell, P Buczkowicz, M Remke, B Golbourn, ... Cancer discovery 4 (10), 1198-1213, 2014 | 76 | 2014 |
