Triggering the interferon antiviral response through an IKK-related pathway S Sharma, BR TenOever, N Grandvaux, GP Zhou, R Lin, J Hiscott Science 300 (5622), 1148-1151, 2003 | 1867 | 2003 |
Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes N Grandvaux, MJ Servant, B tenOever, GC Sen, S Balachandran, ... Journal of virology 76 (11), 5532-5539, 2002 | 640* | 2002 |
ACE2: Evidence of role as entry receptor for SARS-CoV-2 and implications in comorbidities N Zamorano Cuervo, N Grandvaux elife 9, e61390, 2020 | 339 | 2020 |
The interferon antiviral response: from viral invasion to evasion N Grandvaux, MJ Servant, J Hiscott Current opinion in infectious diseases 15 (3), 259-267, 2002 | 324 | 2002 |
Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA MJ Servant, N Grandvaux, D Duguay, R Lin, J Hiscott Journal of Biological Chemistry 278 (11), 9441-9447, 2003 | 275 | 2003 |
Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKε A Breiman, N Grandvaux, R Lin, C Ottone, S Akira, M Yoneyama, T Fujita, ... Journal of virology 79 (7), 3969-3978, 2005 | 236 | 2005 |
Activation of TBK1 and IKKε kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity BR tenOever, S Sharma, W Zou, Q Sun, N Grandvaux, I Julkunen, ... Journal of virology 78 (19), 10636-10649, 2004 | 236 | 2004 |
Recognition of the measles virus nucleocapsid as a mechanism of IRF-3 activation BR tenOever, MJ Servant, N Grandvaux, R Lin, J Hiscott Journal of virology 76 (8), 3659-3669, 2002 | 225 | 2002 |
Multiple signaling pathways leading to the activation of interferon regulatory factor 3 MJ Servant, N Grandvaux, J Hiscott Biochemical pharmacology 64 (5-6), 985-992, 2002 | 203 | 2002 |
Memory CCR6+ CD4+ T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin β7 P Monteiro, A Gosselin, VS Wacleche, M El-Far, EA Said, H Kared, ... The Journal of Immunology 186 (8), 4618-4630, 2011 | 172 | 2011 |
Convergence of the NF‐κB and Interferon Signaling Pathways in the Regulation of Antiviral Defense and Apoptosis J Hiscott, N Grandvaux, S Sharma, BR Tenoever, MJ Servant, R Lin Annals of the New York Academy of Sciences 1010 (1), 237-248, 2003 | 163 | 2003 |
Disruption of NF-κB signaling reveals a novel role for NF-κB in the regulation of TNF-related apoptosis-inducing ligand expression TM Baetu, H Kwon, S Sharma, N Grandvaux, J Hiscott The Journal of Immunology 167 (6), 3164-3173, 2001 | 156 | 2001 |
STAT2 and IRF9: Beyond ISGF3 K Fink, N Grandvaux Jak-stat 2 (4), e27521, 2013 | 153 | 2013 |
Requirement of NOX2 and reactive oxygen species for efficient RIG-I-mediated antiviral response through regulation of MAVS expression A Soucy-Faulkner, E Mukawera, K Fink, A Martel, L Jouan, Y Nzengue, ... PLoS pathogens 6 (6), e1000930, 2010 | 148 | 2010 |
Nuclear accumulation of cRel following C-terminal phosphorylation by TBK1/IKKε J Harris, S Oliere, S Sharma, Q Sun, R Lin, J Hiscott, N Grandvaux The Journal of Immunology 177 (4), 2527-2535, 2006 | 146 | 2006 |
Respiratory syncytial virus-mediated NF-κB p65 phosphorylation at serine 536 is dependent on RIG-I, TRAF6, and IKKβ F Yoboua, A Martel, A Duval, E Mukawera, N Grandvaux Journal of virology 84 (14), 7267-7277, 2010 | 142 | 2010 |
p40phox is phosphorylated on threonine 154 and serine 315 during activation of the phagocyte NADPH oxidase: implication of a protein kinase C-type kinase in the phosphorylation … AP Bouin, N Grandvaux, PV Vignais, A Fuchs Journal of Biological Chemistry 273 (46), 30097-30103, 1998 | 141 | 1998 |
Involvement of the IκB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation A Bibeau-Poirier, SP Gravel, JF Clément, S Rolland, G Rodier, ... The Journal of Immunology 177 (8), 5059-5067, 2006 | 119 | 2006 |
Phosphorylation of IRF-3 on Ser 339 generates a hyperactive form of IRF-3 through regulation of dimerization and CBP association JF Clément, A Bibeau-Poirier, SP Gravel, N Grandvaux, É Bonneil, ... Journal of virology 82 (8), 3984-3996, 2008 | 117 | 2008 |
Histone deacetylase–mediated transcriptional activation reduces proviral loads in HTLV-1–associated myelopathy/tropical spastic paraparesis patients A Lezin, N Gillet, S Olindo, A Signaté, N Grandvaux, O Verlaeten, ... Blood, The Journal of the American Society of Hematology 110 (10), 3722-3728, 2007 | 113 | 2007 |