|Triggering the interferon antiviral response through an IKK-related pathway|
S Sharma, BR TenOever, N Grandvaux, GP Zhou, R Lin, J Hiscott
Science 300 (5622), 1148-1151, 2003
|Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes|
N Grandvaux, MJ Servant, B tenOever, GC Sen, S Balachandran, ...
Journal of virology 76 (11), 5532-5539, 2002
|The interferon antiviral response: from viral invasion to evasion|
N Grandvaux, MJ Servant, J Hiscott
Current opinion in infectious diseases 15 (3), 259-267, 2002
|Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA|
MJ Servant, N Grandvaux, D Duguay, R Lin, J Hiscott
Journal of Biological Chemistry 278 (11), 9441-9447, 2003
|ACE2: Evidence of role as entry receptor for SARS-CoV-2 and implications in comorbidities|
N Zamorano Cuervo, N Grandvaux
Elife 9, e61390, 2020
|Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKε|
A Breiman, N Grandvaux, R Lin, C Ottone, S Akira, M Yoneyama, T Fujita, ...
Journal of virology 79 (7), 3969-3978, 2005
|Recognition of the measles virus nucleocapsid as a mechanism of IRF-3 activation|
BR tenOever, MJ Servant, N Grandvaux, R Lin, J Hiscott
Journal of virology 76 (8), 3659-3669, 2002
|Activation of TBK1 and IKKε kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity|
BR tenOever, S Sharma, W Zou, Q Sun, N Grandvaux, I Julkunen, ...
Journal of virology 78 (19), 10636-10649, 2004
|Multiple signaling pathways leading to the activation of interferon regulatory factor 3|
MJ Servant, N Grandvaux, J Hiscott
Biochemical pharmacology 64 (5-6), 985-992, 2002
|Memory CCR6+ CD4+ T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin β7|
P Monteiro, A Gosselin, VS Wacleche, M El-Far, EA Said, H Kared, ...
The Journal of Immunology 186 (8), 4618-4630, 2011
|Convergence of the NF‐κB and Interferon Signaling Pathways in the Regulation of Antiviral Defense and Apoptosis|
J Hiscott, N Grandvaux, S Sharma, BR Tenoever, MJ Servant, R Lin
Annals of the New York Academy of Sciences 1010 (1), 237-248, 2003
|Disruption of NF-κB signaling reveals a novel role for NF-κB in the regulation of TNF-related apoptosis-inducing ligand expression|
TM Baetu, H Kwon, S Sharma, N Grandvaux, J Hiscott
The Journal of Immunology 167 (6), 3164-3173, 2001
|STAT2 and IRF9: Beyond ISGF3|
K Fink, N Grandvaux
Jak-stat 2 (4), e27521, 2013
|Requirement of NOX2 and reactive oxygen species for efficient RIG-I-mediated antiviral response through regulation of MAVS expression|
A Soucy-Faulkner, E Mukawera, K Fink, A Martel, L Jouan, Y Nzengue, ...
PLoS pathogens 6 (6), e1000930, 2010
|Nuclear accumulation of cRel following C-terminal phosphorylation by TBK1/IKKε|
J Harris, S Olière, S Sharma, Q Sun, R Lin, J Hiscott, N Grandvaux
The Journal of Immunology 177 (4), 2527-2535, 2006
|p40phox is phosphorylated on threonine 154 and serine 315 during activation of the phagocyte NADPH oxidase: implication of a protein kinase c-type kinase in the phosphorylation …|
AP Bouin, N Grandvaux, PV Vignais, A Fuchs
Journal of Biological Chemistry 273 (46), 30097-30103, 1998
|Respiratory syncytial virus-mediated NF-κB p65 phosphorylation at serine 536 is dependent on RIG-I, TRAF6, and IKKβ|
F Yoboua, A Martel, A Duval, E Mukawera, N Grandvaux
Journal of virology 84 (14), 7267-7277, 2010
|Involvement of the IκB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation|
A Bibeau-Poirier, SP Gravel, JF Clément, S Rolland, G Rodier, ...
The Journal of Immunology 177 (8), 5059-5067, 2006
|Phosphorylation of IRF-3 on Ser 339 generates a hyperactive form of IRF-3 through regulation of dimerization and CBP association|
JF Clément, A Bibeau-Poirier, SP Gravel, N Grandvaux, É Bonneil, ...
Journal of virology 82 (8), 3984-3996, 2008
|Histone deacetylase–mediated transcriptional activation reduces proviral loads in HTLV-1–associated myelopathy/tropical spastic paraparesis patients|
A Lezin, N Gillet, S Olindo, A Signaté, N Grandvaux, O Verlaeten, ...
Blood, The Journal of the American Society of Hematology 110 (10), 3722-3728, 2007