Roland Pache
Roland Pache
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Scientific benchmarks for guiding macromolecular energy function improvement
A Leaver-Fay, MJ O’Meara, M Tyka, R Jacak, Y Song, EH Kellogg, ...
Methods in enzymology 523, 2013
Dynamic interactions of proteins in complex networks: a more structured view
A Stein, RA Pache, P Bernado, M Pons, P Aloy
The FEBS journal 276 (19), 5390-5405, 2009
A web resource for standardized benchmark datasets, metrics, and Rosetta protocols for macromolecular modeling and design
S Ó Conchúir, KA Barlow, RA Pache, N Ollikainen, K Kundert, ...
PLOS one 10 (9), e0130433, 2015
Uncovering new substrates for Aurora A kinase
T Sardon, RA Pache, A Stein, H Molina, I Vernos, P Aloy
EMBO reports 11 (12), 977-984, 2010
The role of structural disorder in the rewiring of protein interactions through evolution
R Mosca, RA Pache, P Aloy
Molecular & Cellular Proteomics 11 (7), 2012
Computational design of a modular protein sense-response system
AA Glasgow, YM Huang, DJ Mandell, M Thompson, R Ritterson, ...
Science 366 (6468), 1024-1028, 2019
Engineering a light-activated caspase-3 for precise ablation of neurons in vivo
AD Smart, RA Pache, ND Thomsen, T Kortemme, GW Davis, JA Wells
Proceedings of the National Academy of Sciences 114 (39), E8174-E8183, 2017
NetAligner—a network alignment server to compare complexes, pathways and whole interactomes
RA Pache, A Céol, P Aloy
Nucleic acids research 40 (W1), W157-W161, 2012
A novel framework for the comparative analysis of biological networks
RA Pache, P Aloy
PloS one 7 (2), e31220, 2012
Towards a molecular characterisation of pathological pathways
RA Pache, A Zanzoni, J Naval, JM Mas, P Aloy
FEBS letters 582 (8), 1259-1265, 2008
Incorporating high‐throughput proteomics experiments into structural biology pipelines: Identification of the low‐hanging fruits
RA Pache, P Aloy
Proteomics 8 (10), 1959-1964, 2008
Exploiting gene deletion fitness effects in yeast to understand the modular architecture of protein complexes under different growth conditions
RA Pache, MM Babu, P Aloy
BMC Systems Biology 3 (1), 1-18, 2009
Systematic bioinformatics and experimental validation of yeast complexes reduces the rate of attrition during structural investigations
MA Brooks, K Gewartowski, E Mitsiki, J Létoquart, RA Pache, Y Billier, ...
Structure 18 (9), 1075-1082, 2010
Accurate positioning of functional residues with robotics-inspired computational protein design
C Krivacic, K Kundert, X Pan, RA Pache, L Liu, S O Conchúir, ...
Proceedings of the National Academy of Sciences 119 (11), e2115480119, 2022
Increasing the precision of orthology-based complex prediction through network alignment
RA Pache, P Aloy
PeerJ 2, e413, 2014
Multitasking in the gut: the X-ray structure of the multidomain BbgIII from Bifidobacterium bifidum offers possible explanations for its alternative functions
OV Moroz, E Blagova, AA Lebedev, F Sánchez Rodríguez, DJ Rigden, ...
Acta Crystallographica Section D: Structural Biology 77 (12), 1564-1578, 2021
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