Jason C. Kwan
Jason C. Kwan
Assistant Professor of Drug Discovery, University of Wisconsin-Madison
Verified email at
Cited by
Cited by
Critical Assessment of Metagenome Interpretation: the second round of challenges
F Meyer, A Fritz, ZL Deng, D Koslicki, TR Lesker, A Gurevich, G Robertson, ...
Nature methods 19 (4), 429-440, 2022
Genome streamlining and chemical defense in a coral reef symbiosis
JC Kwan, MS Donia, AW Han, E Hirose, MG Haygood, EW Schmidt
Proceedings of the National Academy of Sciences 109 (50), 20655-20660, 2012
Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor
Y Liu, LA Salvador, S Byeon, Y Ying, JC Kwan, BK Law, J Hong, ...
Journal of Pharmacology and Experimental Therapeutics 335 (2), 351-361, 2010
Lyngbyoic acid, a “tagged” fatty acid from a marine cyanobacterium, disrupts quorum sensing in Pseudomonas aeruginosa
JC Kwan, T Meickle, D Ladwa, M Teplitski, V Paul, H Luesch
Molecular bioSystems 7 (4), 1205-1216, 2011
Grassystatins A− C from Marine Cyanobacteria, Potent Cathepsin E Inhibitors That Reduce Antigen Presentation
JC Kwan, EA Eksioglu, C Liu, VJ Paul, H Luesch
Journal of medicinal chemistry 52 (18), 5732-5747, 2009
An antifungal polyketide associated with horizontally acquired genes supports symbiont-mediated defense in Lagria villosa beetles
LV Flórez, K Scherlach, IJ Miller, A Rodrigues, JC Kwan, C Hertweck, ...
Nature communications 9 (1), 1-10, 2018
Structure and biosynthesis of the antibiotic bottromycin D
Y Hou, MDB Tianero, JC Kwan, TP Wyche, CR Michel, GA Ellis, ...
Organic letters 14 (19), 5050-5053, 2012
Species specificity of symbiosis and secondary metabolism in ascidians
MDB Tianero, JC Kwan, TP Wyche, AP Presson, M Koch, LR Barrows, ...
The ISME journal 9 (3), 615-628, 2015
Isolation and Biological Evaluation of 8-epi-Malyngamide C from the Floridian Marine Cyanobacterium Lyngbya majuscula†
JC Kwan, M Teplitski, SP Gunasekera, VJ Paul, H Luesch
Journal of natural products 73 (3), 463-466, 2010
A bacterial source for mollusk pyrone polyketides
Z Lin, JP Torres, MA Ammon, L Marett, RW Teichert, CA Reilly, JC Kwan, ...
Chemistry & biology 20 (1), 73-81, 2013
Lyngbyastatins 8–10, elastase inhibitors with cyclic depsipeptide scaffolds isolated from the marine cyanobacterium Lyngbya semiplena
JC Kwan, K Taori, VJ Paul, H Luesch
Marine drugs 7 (4), 528-538, 2009
Accessing chemical diversity from the uncultivated symbionts of small marine animals
TE Smith, CD Pond, E Pierce, ZP Harmer, J Kwan, MM Zachariah, ...
Nature chemical biology 14 (2), 179-185, 2018
Molassamide, a Depsipeptide Serine Protease Inhibitor from the Marine Cyanobacterium Dichothrix utahensis
SP Gunasekera, MW Miller, JC Kwan, H Luesch, VJ Paul
Journal of natural products 73 (3), 459-462, 2010
Microbial-derived products as potential new antimicrobials
BS Seal, D Drider, BB Oakley, H Brüssow, D Bikard, JO Rich, S Miller, ...
Veterinary research 49 (1), 1-12, 2018
Total structure determination of grassypeptolide, a new marine cyanobacterial cytotoxin
JC Kwan, JR Rocca, KA Abboud, VJ Paul, H Luesch
Organic letters 10 (5), 789-792, 2008
Autometa: automated extraction of microbial genomes from individual shotgun metagenomes
IJ Miller, ER Rees, J Ross, I Miller, J Baxa, J Lopera, RL Kerby, FE Rey, ...
Nucleic acids research 47 (10), e57-e57, 2019
Grassypeptolides A− C, cytotoxic bis-thiazoline containing marine cyclodepsipeptides
JC Kwan, R Ratnayake, KA Abboud, VJ Paul, H Luesch
The Journal of organic chemistry 75 (23), 8012-8023, 2010
Bacterial endosymbiosis in a chordate host: long-term co-evolution and conservation of secondary metabolism
JC Kwan, EW Schmidt
PloS one 8 (12), e80822, 2013
Horizontal gene transfer to a defensive symbiont with a reduced genome in a multipartite beetle microbiome
SC Waterworth, LV Flórez, ER Rees, C Hertweck, M Kaltenpoth, JC Kwan
MBio 11 (1), e02430-19, 2020
Lack of overt genome reduction in the bryostatin-producing bryozoan symbiont “Candidatus Endobugula sertula”
IJ Miller, N Vanee, SS Fong, GE Lim-Fong, JC Kwan
Applied and environmental microbiology 82 (22), 6573-6583, 2016
The system can't perform the operation now. Try again later.
Articles 1–20