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LALIT KUMAR SHARMA
LALIT KUMAR SHARMA
NextRNA Therapeutics
Verified email at nextrna.com - Homepage
Title
Cited by
Cited by
Year
A therapeutic approach to pantothenate kinase associated neurodegeneration
LK Sharma, C Subramanian, MK Yun, MW Frank, SW White, CO Rock, ...
Nature communications 9 (1), 4399, 2018
802018
Pre-mRNA splicing-modulatory pharmacophores: the total synthesis of herboxidiene, a pladienolide–herboxidiene hybrid analog and related derivatives
C Lagisetti, MV Yermolina, LK Sharma, G Palacios, BJ Prigaro, TR Webb
ACS chemical biology 9 (3), 643-648, 2014
762014
Inhibition or knockdown of ABC transporters enhances susceptibility of adult and juvenile schistosomes to Praziquantel
RS Kasinathan, LK Sharma, C Cunningham, TR Webb, RM Greenberg
PLoS neglected tropical diseases 8 (10), e3265, 2014
652014
Revisiting the role of the immunoproteasome in the activation of the canonical NF-κB pathway
ER Jang, NR Lee, S Han, Y Wu, LK Sharma, KC Carmony, J Marks, ...
Molecular BioSystems 8 (9), 2295-2302, 2012
402012
A selective solvent-free self-condensation of carbonyl compounds utilizing microwave irradiation
LK Sharma, KB Kim, GI Elliott
Green Chemistry 13 (6), 1546-1549, 2011
332011
Allosteric regulation of mammalian pantothenate kinase
C Subramanian, MK Yun, J Yao, LK Sharma, RE Lee, SW White, ...
Journal of Biological Chemistry 291 (42), 22302-22314, 2016
302016
A high-throughput screen reveals new small-molecule activators and inhibitors of pantothenate kinases
LK Sharma, R Leonardi, W Lin, VA Boyd, A Goktug, AA Shelat, T Chen, ...
Journal of Medicinal Chemistry 58 (3), 1563-1568, 2015
302015
Near-Infrared Activity-Based Fluorescent Probe for LMP7: A Chemical Proteomics Tool for Immunoproteasome in Living Cells
LK Sharma, NR Lee, ER Jang, B Lei, CG Zhan, W Lee, KB Kim
Chembiochem: a European journal of chemical biology 13 (13), 1899, 2012
212012
A FRET-based approach for identification of proteasome catalytic subunit composition
JE Park, Y Wu, KC Carmony, Z Miller, LK Sharma, DM Lee, DY Kim, ...
Molecular BioSystems 10 (2), 196-200, 2014
162014
Design and synthesis of molecular probes for the determination of the target of the anthelmintic drug praziquantel
LK Sharma, PM Cupit, T Goronga, TR Webb, C Cunningham
Bioorganic & medicinal chemistry letters 24 (11), 2469-2472, 2014
142014
Identification of Small Molecules Exhibiting Oxacillin Synergy through a Novel Assay for Inhibition of vraTSR Expression in Methicillin-Resistant Staphylococcus …
H Lee, S Boyle-Vavra, J Ren, JA Jarusiewicz, LK Sharma, DT Hoagland, ...
Antimicrobial agents and chemotherapy 63 (9), 10.1128/aac. 02593-18, 2019
132019
The Discovery and Development of Thienopyrimidines as Inhibitors of Helicobacter pylori That Act through Inhibition of the Respiratory Complex I
AK Mugengana, NA Vita, A Brown Gandt, K Moran, G Agyapong, ...
ACS infectious diseases 7 (5), 1044-1058, 2021
102021
Elucidating the Catalytic Subunit Composition of Distinct Proteasome Subtypes: A Crosslinking Approach Employing Bifunctional Activity‐Based Probes
K Cornish Carmony, LK Sharma, DM Lee, JE Park, W Lee, KB Kim
ChemBioChem 16 (2), 284-292, 2015
92015
LipE guided discovery of isopropylphenyl pyridazines as pantothenate kinase modulators
LK Sharma, MK Yun, C Subramanian, R Tangallapally, S Jackowski, ...
Bioorganic & medicinal chemistry 52, 116504, 2021
32021
Small molecule modulators of pantothenate kinases
LK Sharma, RE Lee, CO Rock, S Jackowski, MK Yun, C Subramanian, ...
US Patent 10,899,734, 2021
22021
Methods of treating disorders associated with castor
S Jackowski, CO Rock, RE Lee, LK Sharma, MK Yun, C Subramanian, ...
US Patent 11,547,709, 2023
12023
Development of novel chemical tools for proteasome biology & a new approach to 1-azaspirocyclic ring system
L Kumar
University of Kentucky, 2012
12012
1′-Ethylsulfanyl-1, 1′-bicyclohexyl-2-one
LK Sharma, S Parkin, GI Elliott
Acta Crystallographica Section E: Structure Reports Online 66 (4), o932-o932, 2010
12010
Methods of treating disorders associated with castor
S Jackowski, CO Rock, RE Lee, LK Sharma, MK Yun, C Subramanian, ...
US Patent App. 18/076,044, 2023
2023
Small molecule modulators of pantothenate kinases
LK Sharma, RE Lee, CO Rock, S Jackowski, MK Yun, C Subramanian, ...
US Patent App. 17/120,800, 2021
2021
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